YU44649B - Process for obtaining crystalline cephadroxyl monohydrate - Google Patents
Process for obtaining crystalline cephadroxyl monohydrateInfo
- Publication number
- YU44649B YU44649B YU2427/87A YU242787A YU44649B YU 44649 B YU44649 B YU 44649B YU 2427/87 A YU2427/87 A YU 2427/87A YU 242787 A YU242787 A YU 242787A YU 44649 B YU44649 B YU 44649B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- cefadroxil
- monohydrate
- obtaining crystalline
- crystalline
- cephadroxyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/080,999 US4898938A (en) | 1987-08-03 | 1987-08-03 | Method for preparing crystalline cefadroxil monohydrate |
Publications (2)
Publication Number | Publication Date |
---|---|
YU242787A YU242787A (en) | 1989-02-28 |
YU44649B true YU44649B (en) | 1990-10-31 |
Family
ID=22161022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU2427/87A YU44649B (en) | 1987-08-03 | 1987-12-29 | Process for obtaining crystalline cephadroxyl monohydrate |
Country Status (18)
Country | Link |
---|---|
US (1) | US4898938A (xx) |
EP (1) | EP0302145B1 (xx) |
JP (1) | JP2655664B2 (xx) |
KR (1) | KR960002910B1 (xx) |
CN (1) | CN1016607B (xx) |
AT (1) | ATE105560T1 (xx) |
AU (1) | AU597136B2 (xx) |
CA (1) | CA1285554C (xx) |
DE (1) | DE3789810T2 (xx) |
DK (1) | DK680387A (xx) |
ES (1) | ES2056059T3 (xx) |
FI (1) | FI88043C (xx) |
NO (1) | NO168425C (xx) |
PH (1) | PH23648A (xx) |
PT (1) | PT86526B (xx) |
RU (1) | RU1804461C (xx) |
YU (1) | YU44649B (xx) |
ZA (1) | ZA879701B (xx) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0433428B1 (en) * | 1989-07-10 | 1994-10-12 | Chemferm V.O.F. | A stable form of cephradine, process for its production and intermediates used therein |
IT1251999B (it) * | 1991-11-11 | 1995-05-27 | Opos Biochimica Srl | Forma cristallina di un antibiotico cefalosporinico |
US5589593A (en) * | 1991-11-11 | 1996-12-31 | Biochimica Opos Spa | Crystalline form of a cephalosporin antibiotic |
JP2005530746A (ja) * | 2002-05-03 | 2005-10-13 | エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド | カルベジロールファーマソルブ溶媒和物 |
US20040077849A1 (en) * | 2002-10-16 | 2004-04-22 | Orchid Chemicals & Pharmaceuticals Limited | Process for the preparation of cefadroxil |
US7842791B2 (en) * | 2002-12-19 | 2010-11-30 | Nancy Jean Britten | Dispersible pharmaceutical compositions |
CN1311830C (zh) * | 2004-02-27 | 2007-04-25 | 石药集团中奇制药技术(石家庄)有限公司 | 头孢羟氨苄口腔崩解片及其制备方法 |
WO2007134987A1 (en) * | 2006-05-19 | 2007-11-29 | Dsm Ip Assets B.V. | Process for the crystallisation of cefadroxil |
CN102134250B (zh) * | 2011-01-19 | 2013-03-13 | 天津大学 | 一种头孢羟氨苄单水合物的结晶方法及结晶 |
CN104447795B (zh) * | 2014-11-28 | 2016-08-17 | 珠海金鸿药业股份有限公司 | 一种头孢羟氨苄化合物及其药物组合物 |
CN105534937B (zh) * | 2015-12-30 | 2019-12-03 | 石药集团欧意药业有限公司 | 一种头孢羟氨苄片剂及其制备方法 |
CN106588953B (zh) * | 2016-11-08 | 2018-11-27 | 山东罗欣药业集团恒欣药业有限公司 | 一种抗感染药物头孢羟氨苄晶型化合物及其组合物 |
CN106588954B (zh) * | 2016-11-08 | 2018-11-27 | 山东罗欣药业集团恒欣药业有限公司 | 一种抗感染药物羟氨苄晶体化合物及其组合物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1532682A (en) * | 1976-04-27 | 1978-11-22 | Bristol Myers Co | Process for the preparation of cephadroxil |
US4160863A (en) * | 1977-04-07 | 1979-07-10 | Bristol-Myers Company | Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid |
GB8714180D0 (en) * | 1987-06-17 | 1987-07-22 | Rifar Srl | Anhydrous crystalline cefadroxil |
AU1628588A (en) * | 1987-04-24 | 1988-12-02 | Invenmark Limited | Puzzle |
-
1987
- 1987-08-03 US US07/080,999 patent/US4898938A/en not_active Expired - Fee Related
- 1987-12-22 DK DK680387A patent/DK680387A/da not_active Application Discontinuation
- 1987-12-22 DE DE3789810T patent/DE3789810T2/de not_active Expired - Fee Related
- 1987-12-22 ES ES87119079T patent/ES2056059T3/es not_active Expired - Lifetime
- 1987-12-22 EP EP87119079A patent/EP0302145B1/en not_active Expired - Lifetime
- 1987-12-22 AT AT8787119079T patent/ATE105560T1/de not_active IP Right Cessation
- 1987-12-24 AU AU83045/87A patent/AU597136B2/en not_active Ceased
- 1987-12-28 ZA ZA879701A patent/ZA879701B/xx unknown
- 1987-12-29 YU YU2427/87A patent/YU44649B/xx unknown
- 1987-12-30 CA CA000555571A patent/CA1285554C/en not_active Expired - Lifetime
-
1988
- 1988-01-05 NO NO880026A patent/NO168425C/no unknown
- 1988-01-11 PT PT86526A patent/PT86526B/pt not_active IP Right Cessation
- 1988-01-11 KR KR1019880000123A patent/KR960002910B1/ko not_active IP Right Cessation
- 1988-01-18 RU SU884204000A patent/RU1804461C/ru active
- 1988-02-04 JP JP63024868A patent/JP2655664B2/ja not_active Expired - Lifetime
- 1988-02-10 CN CN88100573A patent/CN1016607B/zh not_active Expired
- 1988-03-07 FI FI881040A patent/FI88043C/fi not_active IP Right Cessation
- 1988-04-04 PH PH36730A patent/PH23648A/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR960002910B1 (ko) | 1996-02-28 |
JPS6442487A (en) | 1989-02-14 |
NO880026D0 (no) | 1988-01-05 |
EP0302145A2 (en) | 1989-02-08 |
JP2655664B2 (ja) | 1997-09-24 |
EP0302145A3 (en) | 1989-08-23 |
PH23648A (en) | 1989-09-27 |
DK680387D0 (da) | 1987-12-22 |
YU242787A (en) | 1989-02-28 |
FI88043C (fi) | 1993-03-25 |
CN1016607B (zh) | 1992-05-13 |
DK680387A (da) | 1989-02-04 |
ZA879701B (en) | 1988-06-23 |
PT86526B (pt) | 1994-10-31 |
KR890003775A (ko) | 1989-04-18 |
DE3789810T2 (de) | 1994-08-18 |
AU8304587A (en) | 1989-02-09 |
DE3789810D1 (de) | 1994-06-16 |
PT86526A (pt) | 1989-09-14 |
FI88043B (fi) | 1992-12-15 |
CA1285554C (en) | 1991-07-02 |
NO168425C (no) | 1992-02-19 |
AU597136B2 (en) | 1990-05-24 |
FI881040A (fi) | 1989-02-04 |
EP0302145B1 (en) | 1994-05-11 |
RU1804461C (ru) | 1993-03-23 |
US4898938A (en) | 1990-02-06 |
ATE105560T1 (de) | 1994-05-15 |
ES2056059T3 (es) | 1994-10-01 |
NO880026L (no) | 1989-02-06 |
FI881040A0 (fi) | 1988-03-07 |
CN1031085A (zh) | 1989-02-15 |
NO168425B (no) | 1991-11-11 |
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