RO94160B - Procedeu de preparare a unor amide ale acidului lisergic - Google Patents

Procedeu de preparare a unor amide ale acidului lisergic

Info

Publication number
RO94160B
RO94160B RO123579A RO12357986A RO94160B RO 94160 B RO94160 B RO 94160B RO 123579 A RO123579 A RO 123579A RO 12357986 A RO12357986 A RO 12357986A RO 94160 B RO94160 B RO 94160B
Authority
RO
Romania
Prior art keywords
amides
preparing
page
optionally
general formula
Prior art date
Application number
RO123579A
Other languages
English (en)
Other versions
RO94160A (ro
Inventor
Hempel Roland
Heidenbluth Karlheinz
Dauth Cristoph
Schmidt Joachim
Bartsch Reni
Resteck Angelika
Hoffmann Wolfgang
Morgenstern Evelyn
Glusa Erika
Grawert Werner
Original Assignee
Veb Arzneimittelwerk Dresden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Veb Arzneimittelwerk Dresden filed Critical Veb Arzneimittelwerk Dresden
Publication of RO94160A publication Critical patent/RO94160A/ro
Publication of RO94160B publication Critical patent/RO94160B/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Inventia se refera la un procedeu pentru prepararea unor amide ale acidului lisergic cu formula generala I (vezi formula în pag.1 a descrierii) prin acilarea compusilor cu formula generala II (vezi formula în pag.1 a descrierii) prin tratarea cu cloruri sau anhidrida ale unor acizi alifatici, aromatici sau heterociclici în mediu de piridina, eventual în amestec cu cloroform sau acetona eventual în prezenta trietilaminei la temperaturi între temperatura camerei si temperatura de reflux, urmata de transformare în mod cunoscut în saruri de aditie cu acizi suportabili fiziologic.
RO123579A 1985-06-10 1986-06-02 Procedeu de preparare a unor amide ale acidului lisergic RO94160B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD27717585A DD238051A1 (de) 1985-06-10 1985-06-10 Verfahren zur herstellung neuer lysergsaeureamide

Publications (2)

Publication Number Publication Date
RO94160A RO94160A (ro) 1988-03-30
RO94160B true RO94160B (ro) 1988-03-31

Family

ID=5568455

Family Applications (1)

Application Number Title Priority Date Filing Date
RO123579A RO94160B (ro) 1985-06-10 1986-06-02 Procedeu de preparare a unor amide ale acidului lisergic

Country Status (9)

Country Link
EP (1) EP0205068B1 (ro)
BG (1) BG44609A1 (ro)
CS (1) CS260497B1 (ro)
DD (1) DD238051A1 (ro)
DE (1) DE3683190D1 (ro)
HU (1) HU196398B (ro)
PL (1) PL149497B1 (ro)
RO (1) RO94160B (ro)
SU (1) SU1481233A1 (ro)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2024003472A (es) 2021-09-20 2024-06-12 Blife Therapeutics Inc Derivados del lsd, sintesis y metodo para el tratamiento de enfermedades y trastornos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3239530A (en) * 1964-01-13 1966-03-08 Sandoz Ltd Process for lysergic acid hydrazides
HU169073B (ro) * 1974-05-28 1976-09-28
DD146460A1 (de) * 1979-11-14 1981-02-11 Reni Bartsch Verfahren zur herstellung 1-benzylierter ergometrinderivate
DE3340025C2 (de) * 1983-11-03 1986-01-09 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen

Also Published As

Publication number Publication date
CS406686A1 (en) 1988-05-16
RO94160A (ro) 1988-03-30
EP0205068B1 (de) 1992-01-02
CS260497B1 (en) 1988-12-15
SU1481233A1 (ru) 1989-05-23
PL149497B1 (en) 1990-02-28
HUT43038A (en) 1987-09-28
EP0205068A3 (en) 1988-01-13
HU196398B (en) 1988-11-28
DD238051A1 (de) 1986-08-06
EP0205068A2 (de) 1986-12-17
DE3683190D1 (de) 1992-02-13
BG44609A1 (ro) 1989-01-16

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