RU1833387C - Cпocoб пoлучehия kpиctaлличeckoй фopmы coльbata moho/ n, n-диmetилфopmamидa/-1-kapбaцeфaлocпopиha - Google Patents

Cпocoб пoлучehия kpиctaлличeckoй фopmы coльbata moho/ n, n-диmetилфopmamидa/-1-kapбaцeфaлocпopиha

Info

Publication number
RU1833387C
RU1833387C SU904831903A SU4831903A RU1833387C RU 1833387 C RU1833387 C RU 1833387C SU 904831903 A SU904831903 A SU 904831903A SU 4831903 A SU4831903 A SU 4831903A RU 1833387 C RU1833387 C RU 1833387C
Authority
RU
Russia
Prior art keywords
mono
carbacephalosporin
solvate
dimethylformamide
synthesis
Prior art date
Application number
SU904831903A
Other languages
English (en)
Inventor
Majkl Ekrich Tomas
Charlz Khojing Richard
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of RU1833387C publication Critical patent/RU1833387C/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
SU904831903A 1988-11-14 1990-12-20 Cпocoб пoлучehия kpиctaлличeckoй фopmы coльbata moho/ n, n-диmetилфopmamидa/-1-kapбaцeфaлocпopиha RU1833387C (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27154588A 1988-11-14 1988-11-14

Publications (1)

Publication Number Publication Date
RU1833387C true RU1833387C (ru) 1993-08-07

Family

ID=23036044

Family Applications (3)

Application Number Title Priority Date Filing Date
SU894742500A RU2002749C1 (ru) 1988-11-14 1989-11-13 Способ получени кристаллической формы сольвата бис(N,N-диметилформамида)-1-карбацефалоспорина
SU904831903A RU1833387C (ru) 1988-11-14 1990-12-20 Cпocoб пoлучehия kpиctaлличeckoй фopmы coльbata moho/ n, n-диmetилфopmamидa/-1-kapбaцeфaлocпopиha
SU904831933A RU2028298C1 (ru) 1988-11-14 1990-12-20 Способ получения кристаллической формы сольвата дигидрата моно(n,n`-диметилформамида)-1-карбацефалоспорина

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SU894742500A RU2002749C1 (ru) 1988-11-14 1989-11-13 Способ получени кристаллической формы сольвата бис(N,N-диметилформамида)-1-карбацефалоспорина

Family Applications After (1)

Application Number Title Priority Date Filing Date
SU904831933A RU2028298C1 (ru) 1988-11-14 1990-12-20 Способ получения кристаллической формы сольвата дигидрата моно(n,n`-диметилформамида)-1-карбацефалоспорина

Country Status (20)

Country Link
EP (1) EP0369687B1 (ru)
JP (1) JP2842640B2 (ru)
KR (1) KR0145556B1 (ru)
CN (1) CN1025333C (ru)
AT (1) ATE136306T1 (ru)
AU (1) AU614440B2 (ru)
CA (1) CA2002597C (ru)
DE (1) DE68926148T2 (ru)
DK (1) DK170701B1 (ru)
ES (1) ES2085281T3 (ru)
GR (1) GR3019677T3 (ru)
HU (1) HU203756B (ru)
IE (1) IE74167B1 (ru)
IL (1) IL92270A (ru)
MX (1) MX18317A (ru)
NZ (1) NZ231369A (ru)
PH (1) PH26103A (ru)
PT (1) PT92270B (ru)
RU (3) RU2002749C1 (ru)
ZA (1) ZA898612B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5097943A (en) * 1986-02-05 1992-03-24 Nisshinbo Industries, Inc. Bobbin transfer appartaus in spinning processes
US5074401A (en) * 1988-06-16 1991-12-24 Kabushiki Kaisha Toyoda Jidoshokki Seisakusho Bobbin-carrying apparatus of a combined fine spinning machine and winder
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
CA2034592C (en) * 1990-01-26 2001-06-05 Ralph R. Pfeiffer Crystalline hydrochloride of new beta-lactam antibiotic and process therefor
US5352782A (en) * 1993-06-04 1994-10-04 Eli Lilly And Company Process for preparing crystalline β-lactam monohydrate
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
WO1999024441A1 (en) * 1997-11-10 1999-05-20 Dsm N.V. Crystallization of beta-lactam compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
MY104063A (en) * 1987-10-06 1993-11-30 Lilly Co Eli Crystalline (beta)-lactam hydrate
IL89150A0 (en) * 1988-02-05 1989-09-10 Lilly Co Eli Crystalline beta-lactam solvate
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic

Also Published As

Publication number Publication date
ES2085281T3 (es) 1996-06-01
DK170701B1 (da) 1995-12-11
GR3019677T3 (en) 1996-07-31
HU203756B (en) 1991-09-30
EP0369687B1 (en) 1996-04-03
PT92270B (pt) 1995-08-09
ZA898612B (en) 1991-07-31
ATE136306T1 (de) 1996-04-15
DK563689A (da) 1990-05-15
IE74167B1 (en) 1997-07-02
DE68926148T2 (de) 1996-09-19
DE68926148D1 (de) 1996-05-09
CA2002597A1 (en) 1990-05-14
IE893641L (en) 1990-05-14
EP0369687A1 (en) 1990-05-23
NZ231369A (en) 1991-03-26
RU2002749C1 (ru) 1993-11-15
HUT52507A (en) 1990-07-28
JP2842640B2 (ja) 1999-01-06
KR900007839A (ko) 1990-06-02
AU4457289A (en) 1990-05-31
CN1025333C (zh) 1994-07-06
RU2028298C1 (ru) 1995-02-09
PH26103A (en) 1992-02-06
CA2002597C (en) 1999-03-23
MX18317A (es) 1993-11-01
DK563689D0 (da) 1989-11-10
AU614440B2 (en) 1991-08-29
CN1042711A (zh) 1990-06-06
KR0145556B1 (ko) 1998-08-17
IL92270A0 (en) 1990-07-26
PT92270A (pt) 1990-05-31
JPH02180882A (ja) 1990-07-13
IL92270A (en) 1994-10-21

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