GR3019677T3 - Solvates of a beta-lactam antibiotic - Google Patents

Solvates of a beta-lactam antibiotic

Info

Publication number
GR3019677T3
GR3019677T3 GR960401054T GR960401054T GR3019677T3 GR 3019677 T3 GR3019677 T3 GR 3019677T3 GR 960401054 T GR960401054 T GR 960401054T GR 960401054 T GR960401054 T GR 960401054T GR 3019677 T3 GR3019677 T3 GR 3019677T3
Authority
GR
Greece
Prior art keywords
beta
solvates
lactam antibiotic
dmf
mono
Prior art date
Application number
GR960401054T
Other languages
English (en)
Inventor
Thomas Michael Eckrich
Richard Charles Hoying
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR3019677T3 publication Critical patent/GR3019677T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
GR960401054T 1988-11-14 1996-04-19 Solvates of a beta-lactam antibiotic GR3019677T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27154588A 1988-11-14 1988-11-14

Publications (1)

Publication Number Publication Date
GR3019677T3 true GR3019677T3 (en) 1996-07-31

Family

ID=23036044

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960401054T GR3019677T3 (en) 1988-11-14 1996-04-19 Solvates of a beta-lactam antibiotic

Country Status (20)

Country Link
EP (1) EP0369687B1 (el)
JP (1) JP2842640B2 (el)
KR (1) KR0145556B1 (el)
CN (1) CN1025333C (el)
AT (1) ATE136306T1 (el)
AU (1) AU614440B2 (el)
CA (1) CA2002597C (el)
DE (1) DE68926148T2 (el)
DK (1) DK170701B1 (el)
ES (1) ES2085281T3 (el)
GR (1) GR3019677T3 (el)
HU (1) HU203756B (el)
IE (1) IE74167B1 (el)
IL (1) IL92270A (el)
MX (1) MX18317A (el)
NZ (1) NZ231369A (el)
PH (1) PH26103A (el)
PT (1) PT92270B (el)
RU (3) RU2002749C1 (el)
ZA (1) ZA898612B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5097943A (en) * 1986-02-05 1992-03-24 Nisshinbo Industries, Inc. Bobbin transfer appartaus in spinning processes
US5074401A (en) * 1988-06-16 1991-12-24 Kabushiki Kaisha Toyoda Jidoshokki Seisakusho Bobbin-carrying apparatus of a combined fine spinning machine and winder
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
CA2034592C (en) * 1990-01-26 2001-06-05 Ralph R. Pfeiffer Crystalline hydrochloride of new beta-lactam antibiotic and process therefor
US5352782A (en) * 1993-06-04 1994-10-04 Eli Lilly And Company Process for preparing crystalline β-lactam monohydrate
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
AU1234999A (en) * 1997-11-10 1999-05-31 Gist-Brocades B.V. Crystallization of beta-lactam compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
EG18529A (en) * 1987-10-06 1993-04-30 Lilly Co Eli Process for preparing b-lactam hydrate
KR890012960A (ko) * 1988-02-05 1989-09-20 매리 앤 터커 결정성 β-락탐 용매화물
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic

Also Published As

Publication number Publication date
CA2002597A1 (en) 1990-05-14
EP0369687B1 (en) 1996-04-03
EP0369687A1 (en) 1990-05-23
ES2085281T3 (es) 1996-06-01
HUT52507A (en) 1990-07-28
RU1833387C (ru) 1993-08-07
IL92270A (en) 1994-10-21
CN1025333C (zh) 1994-07-06
IE893641L (en) 1990-05-14
NZ231369A (en) 1991-03-26
RU2002749C1 (ru) 1993-11-15
PT92270A (pt) 1990-05-31
DE68926148T2 (de) 1996-09-19
MX18317A (es) 1993-11-01
DK170701B1 (da) 1995-12-11
DK563689D0 (da) 1989-11-10
CN1042711A (zh) 1990-06-06
ZA898612B (en) 1991-07-31
AU614440B2 (en) 1991-08-29
AU4457289A (en) 1990-05-31
JP2842640B2 (ja) 1999-01-06
CA2002597C (en) 1999-03-23
DE68926148D1 (de) 1996-05-09
DK563689A (da) 1990-05-15
PT92270B (pt) 1995-08-09
IL92270A0 (en) 1990-07-26
IE74167B1 (en) 1997-07-02
KR0145556B1 (ko) 1998-08-17
RU2028298C1 (ru) 1995-02-09
JPH02180882A (ja) 1990-07-13
ATE136306T1 (de) 1996-04-15
KR900007839A (ko) 1990-06-02
HU203756B (en) 1991-09-30
PH26103A (en) 1992-02-06

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