DK170701B1 - Bis(DMF)- og mono(DMF) solvater af et beta-lactamantibiotikum og fremgangsmåder til fremstilling af sådanne solvater - Google Patents
Bis(DMF)- og mono(DMF) solvater af et beta-lactamantibiotikum og fremgangsmåder til fremstilling af sådanne solvater Download PDFInfo
- Publication number
- DK170701B1 DK170701B1 DK563689A DK563689A DK170701B1 DK 170701 B1 DK170701 B1 DK 170701B1 DK 563689 A DK563689 A DK 563689A DK 563689 A DK563689 A DK 563689A DK 170701 B1 DK170701 B1 DK 170701B1
- Authority
- DK
- Denmark
- Prior art keywords
- dmf
- compound
- formula
- mono
- bis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27154588A | 1988-11-14 | 1988-11-14 | |
US27154588 | 1988-11-14 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK563689D0 DK563689D0 (da) | 1989-11-10 |
DK563689A DK563689A (da) | 1990-05-15 |
DK170701B1 true DK170701B1 (da) | 1995-12-11 |
Family
ID=23036044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK563689A DK170701B1 (da) | 1988-11-14 | 1989-11-10 | Bis(DMF)- og mono(DMF) solvater af et beta-lactamantibiotikum og fremgangsmåder til fremstilling af sådanne solvater |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0369687B1 (el) |
JP (1) | JP2842640B2 (el) |
KR (1) | KR0145556B1 (el) |
CN (1) | CN1025333C (el) |
AT (1) | ATE136306T1 (el) |
AU (1) | AU614440B2 (el) |
CA (1) | CA2002597C (el) |
DE (1) | DE68926148T2 (el) |
DK (1) | DK170701B1 (el) |
ES (1) | ES2085281T3 (el) |
GR (1) | GR3019677T3 (el) |
HU (1) | HU203756B (el) |
IE (1) | IE74167B1 (el) |
IL (1) | IL92270A (el) |
MX (1) | MX18317A (el) |
NZ (1) | NZ231369A (el) |
PH (1) | PH26103A (el) |
PT (1) | PT92270B (el) |
RU (3) | RU2002749C1 (el) |
ZA (1) | ZA898612B (el) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5097943A (en) * | 1986-02-05 | 1992-03-24 | Nisshinbo Industries, Inc. | Bobbin transfer appartaus in spinning processes |
US5074401A (en) * | 1988-06-16 | 1991-12-24 | Kabushiki Kaisha Toyoda Jidoshokki Seisakusho | Bobbin-carrying apparatus of a combined fine spinning machine and winder |
CA2002596A1 (en) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates of b-lactam antibiotic |
CA2034592C (en) * | 1990-01-26 | 2001-06-05 | Ralph R. Pfeiffer | Crystalline hydrochloride of new beta-lactam antibiotic and process therefor |
US5352782A (en) * | 1993-06-04 | 1994-10-04 | Eli Lilly And Company | Process for preparing crystalline β-lactam monohydrate |
US5550231A (en) * | 1993-06-15 | 1996-08-27 | Eli Lilly And Company | Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof |
WO1999024441A1 (en) * | 1997-11-10 | 1999-05-20 | Dsm N.V. | Crystallization of beta-lactam compounds |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO155548C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger. |
EG18529A (en) * | 1987-10-06 | 1993-04-30 | Lilly Co Eli | Process for preparing b-lactam hydrate |
NZ227842A (en) * | 1988-02-05 | 1990-12-21 | Lilly Co Eli | Crystalline 2.5-hydrate form of a beta-lactam |
CA2002596A1 (en) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates of b-lactam antibiotic |
-
1989
- 1989-11-09 CA CA002002597A patent/CA2002597C/en not_active Expired - Fee Related
- 1989-11-10 PT PT92270A patent/PT92270B/pt active IP Right Grant
- 1989-11-10 DE DE68926148T patent/DE68926148T2/de not_active Expired - Fee Related
- 1989-11-10 PH PH39508A patent/PH26103A/en unknown
- 1989-11-10 ES ES89311637T patent/ES2085281T3/es not_active Expired - Lifetime
- 1989-11-10 AT AT89311637T patent/ATE136306T1/de not_active IP Right Cessation
- 1989-11-10 EP EP89311637A patent/EP0369687B1/en not_active Expired - Lifetime
- 1989-11-10 ZA ZA898612A patent/ZA898612B/xx unknown
- 1989-11-10 AU AU44572/89A patent/AU614440B2/en not_active Ceased
- 1989-11-10 IL IL9227089A patent/IL92270A/en not_active IP Right Cessation
- 1989-11-10 DK DK563689A patent/DK170701B1/da not_active IP Right Cessation
- 1989-11-10 MX MX1831789A patent/MX18317A/es unknown
- 1989-11-11 KR KR1019890016364A patent/KR0145556B1/ko not_active IP Right Cessation
- 1989-11-13 NZ NZ231369A patent/NZ231369A/en unknown
- 1989-11-13 JP JP1294752A patent/JP2842640B2/ja not_active Expired - Fee Related
- 1989-11-13 HU HU895881A patent/HU203756B/hu not_active IP Right Cessation
- 1989-11-13 RU SU894742500A patent/RU2002749C1/ru not_active IP Right Cessation
- 1989-11-13 IE IE364189A patent/IE74167B1/en not_active IP Right Cessation
- 1989-11-13 CN CN89108711A patent/CN1025333C/zh not_active Expired - Fee Related
-
1990
- 1990-12-20 RU SU904831903A patent/RU1833387C/ru active
- 1990-12-20 RU SU904831933A patent/RU2028298C1/ru not_active IP Right Cessation
-
1996
- 1996-04-19 GR GR960401054T patent/GR3019677T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ZA898612B (en) | 1991-07-31 |
GR3019677T3 (en) | 1996-07-31 |
JPH02180882A (ja) | 1990-07-13 |
MX18317A (es) | 1993-11-01 |
CN1042711A (zh) | 1990-06-06 |
ES2085281T3 (es) | 1996-06-01 |
PT92270B (pt) | 1995-08-09 |
NZ231369A (en) | 1991-03-26 |
HU203756B (en) | 1991-09-30 |
CA2002597A1 (en) | 1990-05-14 |
DE68926148T2 (de) | 1996-09-19 |
DE68926148D1 (de) | 1996-05-09 |
IE893641L (en) | 1990-05-14 |
IL92270A (en) | 1994-10-21 |
ATE136306T1 (de) | 1996-04-15 |
DK563689A (da) | 1990-05-15 |
AU614440B2 (en) | 1991-08-29 |
PH26103A (en) | 1992-02-06 |
CA2002597C (en) | 1999-03-23 |
JP2842640B2 (ja) | 1999-01-06 |
IE74167B1 (en) | 1997-07-02 |
AU4457289A (en) | 1990-05-31 |
EP0369687B1 (en) | 1996-04-03 |
IL92270A0 (en) | 1990-07-26 |
EP0369687A1 (en) | 1990-05-23 |
DK563689D0 (da) | 1989-11-10 |
KR0145556B1 (ko) | 1998-08-17 |
RU1833387C (ru) | 1993-08-07 |
HUT52507A (en) | 1990-07-28 |
RU2028298C1 (ru) | 1995-02-09 |
CN1025333C (zh) | 1994-07-06 |
PT92270A (pt) | 1990-05-31 |
RU2002749C1 (ru) | 1993-11-15 |
KR900007839A (ko) | 1990-06-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |
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