RO91141B - Procedeu pentru prepararea unor derivati de 2-oxindol-1-carboxamida - Google Patents

Procedeu pentru prepararea unor derivati de 2-oxindol-1-carboxamida

Info

Publication number
RO91141B
RO91141B RO118604A RO11860485A RO91141B RO 91141 B RO91141 B RO 91141B RO 118604 A RO118604 A RO 118604A RO 11860485 A RO11860485 A RO 11860485A RO 91141 B RO91141 B RO 91141B
Authority
RO
Romania
Prior art keywords
phenyl
preparation
carboxamide derivatives
trifluoromethyl
methyl
Prior art date
Application number
RO118604A
Other languages
English (en)
Romanian (ro)
Other versions
RO91141A (ro
Inventor
Saul Bernard Kadin
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of RO91141A publication Critical patent/RO91141A/ro
Publication of RO91141B publication Critical patent/RO91141B/ro

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/60Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RO118604A 1984-05-04 1985-05-03 Procedeu pentru prepararea unor derivati de 2-oxindol-1-carboxamida RO91141B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60735684A 1984-05-04 1984-05-04

Publications (2)

Publication Number Publication Date
RO91141A RO91141A (ro) 1987-06-30
RO91141B true RO91141B (ro) 1987-07-03

Family

ID=24431933

Family Applications (2)

Application Number Title Priority Date Filing Date
RO123678A RO94455B (ro) 1984-05-04 1985-05-03 Procedeu pentru prepararea unor derivati de 2-oxindol-1-carboxamida
RO118604A RO91141B (ro) 1984-05-04 1985-05-03 Procedeu pentru prepararea unor derivati de 2-oxindol-1-carboxamida

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RO123678A RO94455B (ro) 1984-05-04 1985-05-03 Procedeu pentru prepararea unor derivati de 2-oxindol-1-carboxamida

Country Status (25)

Country Link
JP (1) JPS60243068A (xx)
KR (1) KR870000497B1 (xx)
AR (1) AR241159A1 (xx)
BG (2) BG60208B2 (xx)
CS (1) CS252828B2 (xx)
DD (1) DD232916A5 (xx)
EG (1) EG17193A (xx)
ES (2) ES8609248A1 (xx)
FI (1) FI80016C (xx)
HU (1) HU196057B (xx)
IE (1) IE851103L (xx)
IN (1) IN161509B (xx)
MA (1) MA20424A1 (xx)
MW (1) MW1685A1 (xx)
MX (1) MX5839A (xx)
NO (1) NO163132C (xx)
OA (1) OA08098A (xx)
PL (2) PL145416B1 (xx)
PT (1) PT80375B (xx)
RO (2) RO94455B (xx)
RU (1) RU2017729C1 (xx)
SU (1) SU1468413A3 (xx)
YU (1) YU44998B (xx)
ZA (1) ZA853324B (xx)
ZW (1) ZW7885A1 (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
IL95880A (en) * 1989-10-13 1995-12-31 Pfizer Use of 3-Transformed History of 2-Oxindole for the Preparation of Pharmaceuticals for Inhibition of Interlaukio-1 Biosynthesis

Also Published As

Publication number Publication date
RO94455B (ro) 1988-07-01
HUT37754A (en) 1986-02-28
MW1685A1 (en) 1986-09-10
CS252828B2 (en) 1987-10-15
YU73085A (en) 1988-04-30
FI80016C (fi) 1990-04-10
PL145416B1 (en) 1988-09-30
PL257892A1 (en) 1986-10-07
BG60208B2 (en) 1993-12-30
IN161509B (xx) 1987-12-19
RO94455A (ro) 1988-06-30
FI851756L (fi) 1985-11-05
ES8609248A1 (es) 1986-07-16
YU44998B (en) 1991-06-30
AR241159A1 (es) 1991-12-30
ZA853324B (en) 1986-12-30
CS320285A2 (en) 1987-03-12
NO163132C (no) 1990-04-11
PT80375A (en) 1985-05-01
KR850008154A (ko) 1985-12-13
JPH0335315B2 (xx) 1991-05-27
PL147508B1 (en) 1989-06-30
MX5839A (es) 1993-11-01
AR241159A2 (es) 1991-12-30
ZW7885A1 (en) 1985-07-24
HU196057B (en) 1988-09-28
RO91141A (ro) 1987-06-30
JPS60243068A (ja) 1985-12-03
DD232916A5 (de) 1986-02-12
KR870000497B1 (ko) 1987-03-12
RU2017729C1 (ru) 1994-08-15
EG17193A (en) 1990-08-30
NO851774L (no) 1985-11-05
MA20424A1 (fr) 1985-12-31
FI80016B (fi) 1989-12-29
ES551275A0 (es) 1987-07-16
BG60207B2 (en) 1993-12-30
OA08098A (fr) 1987-03-31
PL253203A1 (en) 1986-06-17
IE851103L (en) 1985-11-04
ES542813A0 (es) 1986-07-16
FI851756A0 (fi) 1985-05-03
PT80375B (pt) 1987-09-30
NO163132B (no) 1990-01-02
SU1468413A3 (ru) 1989-03-23
ES8707182A1 (es) 1987-07-16

Similar Documents

Publication Publication Date Title
PT944617E (pt) Cristais de derivados de benzimidazole e sua producao
NO965524L (no) Tri-substituerte fenylderivater anvendelige som PDE IV inhibitorer
DK104292A (da) Heterocycliske forbindelser og fremgangsmaade til deres fremstilling
NO914558D0 (no) Fremstilling og anvendelse av kondenserte heterocykliske forbindelse
KR860004918A (ko) 트리사이클로 화합물의 제조방법
ES8704924A1 (es) Un procedimiento para la preparacion de derivados de benzotiazol y benzotiofeno
BG34615A3 (en) Method for preparing 1- oxides of penicillanic acid
SE8401463D0 (sv) Novel thiazoline derivatives, a process for their preparation and pharmaceutical compositions containing them
AT380471B (de) Verfahren zur herstellung von neuen 2-oxoazetidin-derivate
BG42003A3 (en) Method for preparing pyridyl compounds
RO93218B (ro) Procedeu pentru prepararea unor derivati de 2-oxindol
MY101142A (en) 1, 4-dihydropyridine derivative, process for production thereof, and pharmaceutical use thereof.
BG31227A4 (bg) Метод за получаване на рацемични или оптично активни пирамидо (1,2 а)хетероциклични съединения
GR1000156B (el) ΜΕΘΟΔΟΣ ΠΑΡΑΣΚΕΥΗΣ ΝΕΩΝ ΠΑΡΑΓΩΓΩΝ ΤΡΙΚΥΚΛΙΚΩΝ ΑΜΙΝΩΝ ΤΗΣ ΤΕΤΡΑΥΔΡΟ-5,6,7,8ΝΑΦΘΟ[2,3b] ΔΙΥΔΡΟ-2,3 ΦΟΥΡΑΝΗΣ & ΤΗΣ ΤΕΤΡΑΥΔΡΟ-6,7,8,9 5Η-ΒΕΝΖΟΚΥΚΛΟΕΠΤΑ[2,3Β] ΔΙΥΔΡΟ-2,3 ΦΟΥΡΑΝΗΣ.
RO91141B (ro) Procedeu pentru prepararea unor derivati de 2-oxindol-1-carboxamida
RO81937B (ro) Procedeu pentru prepararea unor derivati ai acidului 7 beta - aminotiazolil -acetamido-3-cefem-4-carboxilic
BG41127A3 (en) Method for preparing 1, 4- dihydropyridine derivatives
ES472044A1 (es) Procedimiento para la obtencion de penicilinas y cefaloespo-rinas
DE3161175D1 (en) 4,4-disubstituted spiro-1,4-dihydropyridines, process for producing them and their use as intermediates
ES8505937A1 (es) Un metodo para la preparacion de una 2-metil-4-hidroxi-2h-1, 2-benzotiacin-1, 1-dioxido-3-(n-2-piridil)-carboxamida
RO85819B (ro) Procedeu de preparare a unor derivati de metil-chinoxalin-1, 4-dioxid
IS3870A (is) Aðferð til framleiðslu Azetidinone úrefna, gagnlegra í tilreiðslu Carbapenem sýklalyfja
HUT34316A (en) Process for producing heterocyclic hydroximidates and thiohydroximidates and their carbamate-ester derivatives
TH9859EX (th) กรรมวิธีสำหรับเตรียมอนุพันธ์ต่างๆ ของ n-(4-พิเพอริดินิล (ไดไฮโดรเบนโซฟิวรานหรือไดไฮโดร -2h-เบนโซพิราน) คาร์บอกซามีด
RO92699B1 (ro) Procedeu de obtinere a unor n-metil-bis-(beta-propionati de alchil)-amine