RO88924A - Procedeu de obtinere a unui preparat de cefaclor cu actiune prelungita - Google Patents

Procedeu de obtinere a unui preparat de cefaclor cu actiune prelungita

Info

Publication number
RO88924A
RO88924A RO84114861A RO11486184A RO88924A RO 88924 A RO88924 A RO 88924A RO 84114861 A RO84114861 A RO 84114861A RO 11486184 A RO11486184 A RO 11486184A RO 88924 A RO88924 A RO 88924A
Authority
RO
Romania
Prior art keywords
cephachlore
prepare
obtaining
prolonged action
cefaclor
Prior art date
Application number
RO84114861A
Other languages
English (en)
French (fr)
Romanian (ro)
Inventor
Sakamoto Teruo
Kawai Sadao
Noda Kinzaburo
Takeda Toyohico
Kato Hiroshi
Original Assignee
Shionogi And Co.Ltd,Jp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi And Co.Ltd,Jp filed Critical Shionogi And Co.Ltd,Jp
Publication of RO88924A publication Critical patent/RO88924A/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RO84114861A 1983-06-15 1984-06-13 Procedeu de obtinere a unui preparat de cefaclor cu actiune prelungita RO88924A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58108289A JPS601128A (ja) 1983-06-15 1983-06-15 作用持続型セフアクロル製剤

Publications (1)

Publication Number Publication Date
RO88924A true RO88924A (ro) 1986-04-30

Family

ID=14480890

Family Applications (1)

Application Number Title Priority Date Filing Date
RO84114861A RO88924A (ro) 1983-06-15 1984-06-13 Procedeu de obtinere a unui preparat de cefaclor cu actiune prelungita

Country Status (23)

Country Link
US (1) US4713247A (enExample)
EP (1) EP0129382B1 (enExample)
JP (1) JPS601128A (enExample)
KR (1) KR910004573B1 (enExample)
AT (1) ATE56869T1 (enExample)
AU (1) AU568654B2 (enExample)
BG (1) BG60261B2 (enExample)
CA (1) CA1213218A (enExample)
DD (1) DD216163A5 (enExample)
DE (1) DE3483282D1 (enExample)
DK (2) DK170922B1 (enExample)
ES (1) ES8602407A1 (enExample)
FI (1) FI84556C (enExample)
GB (1) GB2141342B (enExample)
GR (1) GR81598B (enExample)
HU (1) HU193434B (enExample)
IE (1) IE58278B1 (enExample)
IL (1) IL72083A (enExample)
NZ (1) NZ208345A (enExample)
PH (1) PH19902A (enExample)
PT (1) PT78699B (enExample)
RO (1) RO88924A (enExample)
ZA (1) ZA844357B (enExample)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229132A (en) * 1985-02-22 1993-07-20 Grimberg Georges Serge Non-absorbable gastrointestinal medicament provided for treating the two levels of the digestive tract at the same time
JPS61210025A (ja) * 1985-03-14 1986-09-18 Teisan Seiyaku Kk 安定化された抗生物質複合顆粒製剤
JPS62226926A (ja) * 1986-03-27 1987-10-05 Teisan Seiyaku Kk 持続性複合顆粒剤
AU591248B2 (en) * 1986-03-27 1989-11-30 Kinaform Technology, Inc. Sustained-release pharaceutical preparation
JPH0714863B2 (ja) * 1986-06-02 1995-02-22 忠生 白石 時差溶解性の入浴剤
US4968508A (en) * 1987-02-27 1990-11-06 Eli Lilly And Company Sustained release matrix
IL85538A (en) * 1987-02-27 1991-09-16 Lilly Co Eli Sustained release matrix tablet formulations containing hydrophilic and enteric polymers
BE1002079A4 (fr) * 1988-07-01 1990-06-19 S M B Lab Composition pharmaceutique d'erythromycine a liberation prolongee, sa preparation et son utilisation.
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5122384A (en) * 1989-05-05 1992-06-16 Kv Pharmaceutical Company Oral once-per-day organic nitrate formulation which does not induce tolerance
AU8219191A (en) * 1990-06-14 1992-01-07 Kalmo Enterprises, Inc. Stable aqueous drug suspensions
GB9318641D0 (en) * 1993-09-08 1993-10-27 Edko Trading Representation Compositions
ES2079327B1 (es) * 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.
WO1997033569A1 (de) * 1996-03-13 1997-09-18 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH Arzneimittelzubereitung für ace-hemmer
US5948440A (en) * 1997-12-17 1999-09-07 Ranbaxy Laboratories Limited Modified release matrix formulation of cefaclor and cephalexin
ZA98728B (en) * 1998-01-29 1998-10-28 Ranbaxy Lab Ltd Modified release matrix formulations of cefactor and cephalexin
KR100296413B1 (ko) * 1998-04-01 2001-11-14 김선진 세파클러함유서방성정제
US20030170181A1 (en) * 1999-04-06 2003-09-11 Midha Kamal K. Method for preventing abuse of methylphenidate
EP1191924A4 (en) 1999-04-06 2005-02-09 Pharmaquest Ltd PHARMACEUTICAL DOSAGE FORM FOR INTERMITTENT ADMINISTRATION OF (D-THREO) -METHYLPHENIDATE AND A SECOND STIMULANT OF THE CENTRAL NERVOUS SYSTEM
EP1180022A4 (en) * 1999-05-14 2004-01-07 Lilly Co Eli PROCESS FOR THE MASS PRODUCTION OF PHARMACEUTICAL MATERIAL WITH UNIFORM SOLUBILITY
US6596307B1 (en) 1999-06-15 2003-07-22 Eli Lilly And Company Process for preparing pharmaceutical bulk material having uniform dissolution
JP2003523378A (ja) * 2000-02-24 2003-08-05 アドバンシス ファーマシューティカル コーポレイション 治療剤製品、その使用及び製剤形態
WO2001062231A1 (en) * 2000-02-24 2001-08-30 Advancis Pharmaceutical Corporation Antibiotic composition with inhibitor
AU3984101A (en) * 2000-02-24 2001-09-03 Advanced Pharma Inc Antibiotic and antifungal compositions
US7025989B2 (en) * 2000-02-24 2006-04-11 Advancis Pharmaceutical Corp. Multiple-delayed released antibiotic product, use and formulation thereof
US6991807B2 (en) * 2000-02-24 2006-01-31 Advancis Pharmaceutical, Corp. Antibiotic composition
WO2002056867A2 (en) * 2001-01-18 2002-07-25 Natco Pharma Limited Extended release pharmaceutical compositions containing beta-lactam antibiotics
WO2003075852A2 (en) * 2002-03-07 2003-09-18 Advancis Pharmaceuticals Corporation Antibiotic composition
AU2003219184A1 (en) * 2002-05-09 2003-11-11 Diffucap-Chemobras Quimica E Farmaceutica, Ltda. Novel method of preparing programmed-release compositions containing (s)-1-(n-(1-(ethoxycarbonyl)-3-phenylpropyl)-l-alanyl)-l-proline and the product thus obtained
CA2533178C (en) * 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2006528185A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
CA2533292C (en) * 2003-07-21 2013-12-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
EP1653924A4 (en) * 2003-08-12 2009-09-09 Middlebrook Pharmaceuticals In ANTIBIOTICS, USE AND FORMULATION ASSOCIATED
EP1658034A4 (en) * 2003-08-29 2011-06-22 Middlebrook Pharmaceuticals Inc ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION
JP2007513869A (ja) * 2003-09-15 2007-05-31 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
BR0318535A (pt) * 2003-09-30 2006-09-12 Lupin Ltd composição farmacêutica para o envio controlado de droga, processo para a preparação de uma composição farmacêutica e composição de liberação controlada
US20080069870A1 (en) * 2005-04-12 2008-03-20 Elan Corporation Pic Controlled Release Compositions Comprising a Cephalosporin for the Treatment of a Bacterial Infection
US20060287212A1 (en) * 2005-06-02 2006-12-21 Novozymes A/S Blends of inactive particles and active particles
CN101188997A (zh) 2005-06-02 2008-05-28 诺维信公司 非活性粒子和活性粒子的混合物
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
PL3351240T3 (pl) 2009-05-19 2019-09-30 Celgene Corporation Preparaty 4-amino-2-(2,6-dioksopiperydyn-3-ylo)izoindolino-1,3-dionu
WO2013096444A1 (en) * 2011-12-19 2013-06-27 Salix Pharmaceuticals, Ltd. Methods for treatment and prevention of opioid induced constipation using oral compositions of methylnaltrexone
CA2936746C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
CN104688701A (zh) * 2015-03-20 2015-06-10 江苏亚邦强生药业有限公司 一种头孢克洛片剂及其制备方法
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
CN110408670A (zh) * 2019-08-19 2019-11-05 苏州盛达药业有限公司 一种酶催化合成头孢克洛的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2738303A (en) * 1952-07-18 1956-03-13 Smith Kline French Lab Sympathomimetic preparation
US3906086A (en) * 1971-07-19 1975-09-16 Richard G Powers Timed-release aspirin
JPS52139713A (en) * 1976-05-13 1977-11-21 Shionogi & Co Ltd Sustained release cefalexin preparations
US4250166A (en) * 1977-05-27 1981-02-10 Shionogi & Co., Ltd. Long acting preparation of cefalexin for effective treatments of bacterial infection sensitive to cefalexin
GR74995B (enExample) * 1980-08-27 1984-07-12 Ciba Geigy Ag
JPS5826816A (ja) * 1981-08-11 1983-02-17 Teisan Seiyaku Kk 球形顆粒からなる持続性複合顆粒剤

Also Published As

Publication number Publication date
ES533901A0 (es) 1985-12-01
KR850000242A (ko) 1985-02-26
NZ208345A (en) 1986-12-05
ES8602407A1 (es) 1985-12-01
DE3483282D1 (de) 1990-10-31
AU2941884A (en) 1984-12-20
FI842406L (fi) 1984-12-16
JPS6232166B2 (enExample) 1987-07-13
PT78699A (pt) 1985-01-01
IE841444L (en) 1984-12-15
AU568654B2 (en) 1988-01-07
FI84556B (fi) 1991-09-13
KR910004573B1 (ko) 1991-07-06
GR81598B (enExample) 1984-12-11
BG60261B1 (bg) 1994-03-31
IL72083A0 (en) 1984-10-31
BG60261B2 (en) 1994-03-31
EP0129382B1 (en) 1990-09-26
GB8414633D0 (en) 1984-07-11
GB2141342A (en) 1984-12-19
ZA844357B (en) 1985-06-26
DK291884A (da) 1984-12-16
ATE56869T1 (de) 1990-10-15
US4713247A (en) 1987-12-15
IE58278B1 (en) 1993-08-25
IL72083A (en) 1987-10-30
GB2141342B (en) 1986-11-12
PT78699B (en) 1986-07-15
DK170922B1 (da) 1996-03-18
EP0129382A2 (en) 1984-12-27
EP0129382A3 (en) 1986-07-09
HU193434B (en) 1987-10-28
JPS601128A (ja) 1985-01-07
CA1213218A (en) 1986-10-28
DD216163A5 (de) 1984-12-05
FI842406A0 (fi) 1984-06-13
FI84556C (fi) 1991-12-27
HUT34692A (en) 1985-04-28
PH19902A (en) 1986-08-13
DK291884D0 (da) 1984-06-14

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