RO72475A - Procedeu de obtinere a unor derivati de pirimidina cu activitate farmacologica - Google Patents
Procedeu de obtinere a unor derivati de pirimidina cu activitate farmacologicaInfo
- Publication number
- RO72475A RO72475A RO7688851A RO8885176A RO72475A RO 72475 A RO72475 A RO 72475A RO 7688851 A RO7688851 A RO 7688851A RO 8885176 A RO8885176 A RO 8885176A RO 72475 A RO72475 A RO 72475A
- Authority
- RO
- Romania
- Prior art keywords
- pharmacological activity
- pyrimidine derivatives
- obtaining
- obtaining pyrimidine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5300175 | 1975-12-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
RO72475A true RO72475A (ro) | 1982-10-26 |
Family
ID=10466233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RO7688851A RO72475A (ro) | 1975-12-29 | 1976-12-27 | Procedeu de obtinere a unor derivati de pirimidina cu activitate farmacologica |
Country Status (37)
Country | Link |
---|---|
JP (1) | JPS5283388A (ja) |
AR (1) | AR222290A1 (ja) |
AT (1) | AT360024B (ja) |
AU (1) | AU508123B2 (ja) |
BE (1) | BE849810A (ja) |
BG (1) | BG29722A3 (ja) |
CA (1) | CA1073458A (ja) |
CH (1) | CH631981A5 (ja) |
CS (1) | CS203995B2 (ja) |
DD (1) | DD128588A5 (ja) |
DE (1) | DE2658267A1 (ja) |
DK (1) | DK587076A (ja) |
EG (1) | EG12439A (ja) |
ES (1) | ES454656A1 (ja) |
FI (1) | FI62668C (ja) |
FR (1) | FR2336935A1 (ja) |
GR (1) | GR62441B (ja) |
HU (1) | HU175171B (ja) |
IE (1) | IE45082B1 (ja) |
IL (1) | IL51040A (ja) |
IT (2) | IT1124740B (ja) |
LU (1) | LU76481A1 (ja) |
MW (1) | MW5076A1 (ja) |
MX (1) | MX5119E (ja) |
NL (1) | NL7614538A (ja) |
NO (1) | NO146396C (ja) |
NZ (1) | NZ182759A (ja) |
OA (1) | OA05526A (ja) |
PH (1) | PH14723A (ja) |
PL (1) | PL104376B1 (ja) |
PT (1) | PT65949B (ja) |
RO (1) | RO72475A (ja) |
SE (1) | SE431544B (ja) |
SU (1) | SU791235A3 (ja) |
YU (1) | YU311676A (ja) |
ZA (1) | ZA767198B (ja) |
ZM (1) | ZM14376A1 (ja) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ186511A (en) | 1977-03-19 | 1980-11-14 | Smith Kline French Lab | 3-substituted alkylamino-6-substituted alkyl-1,2,4-triazin-5-ones and pharmaceutical compositions 3-substituted thio-1,2,4-triazin-5-ones |
IL56265A (en) * | 1977-12-28 | 1982-08-31 | Om Lab Sa | Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor |
IN151188B (ja) * | 1978-02-13 | 1983-03-05 | Smith Kline French Lab | |
US4539207A (en) * | 1978-02-13 | 1985-09-03 | Smith Kline & French Laboratories Limited | Pyrimidine compounds |
AU527202B2 (en) * | 1978-04-11 | 1983-02-24 | Smith Kline & French Laboratories Limited | 2-aminopyrimidones |
ZA792607B (en) * | 1978-05-30 | 1980-07-30 | Smith Kline French Lab | Nitro compounds |
ZA793392B (en) * | 1978-07-15 | 1980-08-27 | Smith Kline French Lab | Isoureas and isothioureas |
US4309435A (en) | 1978-10-16 | 1982-01-05 | Imperial Chemical Industries Ltd. | Antisecretory guanidine derivatives and pharmaceutical compositions containing them |
US4374836A (en) | 1978-10-16 | 1983-02-22 | Imperial Chemical Industries Ltd. | Antisecretory heterocyclic derivatives, process for their manufacture and pharmaceutical compositions containing them |
US4496567A (en) * | 1978-11-13 | 1985-01-29 | Smith Kline & French Laboratories Limited | Phenyl alkylaminopyrimidones |
US4521418A (en) * | 1979-02-21 | 1985-06-04 | Smith Kline & French Laboratories Limited | Guanidinothiazolyl derivatives |
US4255428A (en) | 1979-03-24 | 1981-03-10 | Smith Kline & French Laboratories Limited | 5-(Hydroxypyridylalkyl)-4-pyrimidones |
JPS55133379A (en) * | 1979-04-05 | 1980-10-17 | Smith Kline French Lab | Pyrimidone compound |
DE2962542D1 (en) * | 1979-04-11 | 1982-06-03 | Smith Kline French Lab | Pyrimidone derivatives, process for preparing them and pharmaceutical compositions containing them |
JPS55145683A (en) * | 1979-04-26 | 1980-11-13 | Smith Kline French Lab | Pyrimidone derivative |
CA1155842A (en) * | 1980-03-29 | 1983-10-25 | Thomas H. Brown | Compounds |
ZW21281A1 (en) * | 1980-10-01 | 1981-11-18 | Smith Kline French Lab | Amine derivatives |
IE53068B1 (en) * | 1981-06-15 | 1988-05-25 | Merck & Co Inc | Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors |
PT75074B (en) * | 1981-06-27 | 1986-02-26 | Smith Kline French Lab | Process for preparing certain pyrimidone derivatives and compositions containing them |
US6417366B2 (en) * | 1999-06-24 | 2002-07-09 | Abbott Laboratories | Preparation of quinoline-substituted carbonate and carbamate derivatives |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1419994A (en) * | 1973-05-03 | 1976-01-07 | Smith Kline French Lab | Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them |
IN146736B (ja) * | 1975-10-02 | 1979-08-25 | Smith Kline French Lab |
-
1976
- 1976-11-22 MW MW50/76A patent/MW5076A1/xx unknown
- 1976-11-29 NZ NZ182759A patent/NZ182759A/xx unknown
- 1976-12-02 IL IL51040A patent/IL51040A/xx unknown
- 1976-12-02 ZA ZA767198A patent/ZA767198B/xx unknown
- 1976-12-08 CA CA267,385A patent/CA1073458A/en not_active Expired
- 1976-12-09 IT IT30235/76A patent/IT1124740B/it active
- 1976-12-10 PT PT65949A patent/PT65949B/pt unknown
- 1976-12-17 PH PH19265A patent/PH14723A/en unknown
- 1976-12-17 ZM ZM143/76A patent/ZM14376A1/xx unknown
- 1976-12-21 FI FI763664A patent/FI62668C/fi not_active IP Right Cessation
- 1976-12-22 YU YU03116/76A patent/YU311676A/xx unknown
- 1976-12-22 IE IE2814/76A patent/IE45082B1/en unknown
- 1976-12-22 DE DE19762658267 patent/DE2658267A1/de not_active Ceased
- 1976-12-22 GR GR52462A patent/GR62441B/el unknown
- 1976-12-23 CH CH1627876A patent/CH631981A5/de not_active IP Right Cessation
- 1976-12-23 JP JP15611076A patent/JPS5283388A/ja active Granted
- 1976-12-23 AT AT960876A patent/AT360024B/de not_active IP Right Cessation
- 1976-12-23 BE BE173597A patent/BE849810A/xx not_active IP Right Cessation
- 1976-12-27 RO RO7688851A patent/RO72475A/ro unknown
- 1976-12-28 LU LU76481A patent/LU76481A1/xx unknown
- 1976-12-28 HU HU76SI1556A patent/HU175171B/hu unknown
- 1976-12-28 BG BG035033A patent/BG29722A3/xx unknown
- 1976-12-28 SE SE7614620A patent/SE431544B/xx not_active IP Right Cessation
- 1976-12-28 PL PL1976194772A patent/PL104376B1/pl unknown
- 1976-12-28 EG EG803/76A patent/EG12439A/xx active
- 1976-12-28 NO NO764370A patent/NO146396C/no unknown
- 1976-12-29 SU SU762434655A patent/SU791235A3/ru active
- 1976-12-29 FR FR7639465A patent/FR2336935A1/fr active Granted
- 1976-12-29 CS CS768760A patent/CS203995B2/cs unknown
- 1976-12-29 AR AR266049A patent/AR222290A1/es active
- 1976-12-29 ES ES454656A patent/ES454656A1/es not_active Expired
- 1976-12-29 OA OA56028A patent/OA05526A/xx unknown
- 1976-12-29 DD DD7600196703A patent/DD128588A5/xx unknown
- 1976-12-29 NL NL7614538A patent/NL7614538A/xx not_active Application Discontinuation
- 1976-12-29 DK DK587076A patent/DK587076A/da not_active Application Discontinuation
- 1976-12-30 AU AU20976/76A patent/AU508123B2/en not_active Expired
-
1977
- 1977-01-03 MX MX775273U patent/MX5119E/es unknown
-
1979
- 1979-01-05 IT IT7919107A patent/IT7919107A0/it unknown
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