RO110493B1 - Derivati de benzimidazol si procedee pentru prepararea acestora - Google Patents
Derivati de benzimidazol si procedee pentru prepararea acestora Download PDFInfo
- Publication number
- RO110493B1 RO110493B1 RO92-01581A RO9201581A RO110493B1 RO 110493 B1 RO110493 B1 RO 110493B1 RO 9201581 A RO9201581 A RO 9201581A RO 110493 B1 RO110493 B1 RO 110493B1
- Authority
- RO
- Romania
- Prior art keywords
- methyl
- benzimidazole
- dimethoxy
- sulfinyl
- pyridinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9002206A SE9002206D0 (sv) | 1990-06-20 | 1990-06-20 | New compounds |
| PCT/SE1991/000415 WO1991019711A1 (en) | 1990-06-20 | 1991-06-11 | Substituted benzimidazoles, process for their preparation and their pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RO110493B1 true RO110493B1 (ro) | 1996-01-30 |
Family
ID=20379831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO92-01581A RO110493B1 (ro) | 1990-06-20 | 1991-06-11 | Derivati de benzimidazol si procedee pentru prepararea acestora |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP0535081A1 (lv) |
| JP (1) | JPH05507713A (lv) |
| CN (1) | CN1058212A (lv) |
| AP (1) | AP215A (lv) |
| AU (1) | AU649453B2 (lv) |
| BG (1) | BG97200A (lv) |
| CA (1) | CA2083714A1 (lv) |
| CZ (1) | CZ279772B6 (lv) |
| FI (1) | FI925766A (lv) |
| HU (1) | HUT62881A (lv) |
| IE (1) | IE912025A1 (lv) |
| IL (1) | IL98470A0 (lv) |
| IS (1) | IS3721A7 (lv) |
| LT (2) | LT3977B (lv) |
| LV (1) | LV10953A (lv) |
| MA (1) | MA22199A1 (lv) |
| NO (1) | NO924775D0 (lv) |
| NZ (1) | NZ238546A (lv) |
| OA (1) | OA09682A (lv) |
| PT (1) | PT98035A (lv) |
| RO (1) | RO110493B1 (lv) |
| SE (1) | SE9002206D0 (lv) |
| TN (1) | TNSN91049A1 (lv) |
| TW (1) | TW216418B (lv) |
| WO (1) | WO1991019711A1 (lv) |
| YU (1) | YU104191A (lv) |
| ZA (2) | ZA914297B (lv) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9002043D0 (sv) * | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
| SE9103776D0 (sv) * | 1991-12-19 | 1991-12-19 | Astra Ab | New compounds |
| IS4232A (is) * | 1993-12-06 | 1995-06-07 | Astra Aktiebolag | Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun |
| SE9500422D0 (sv) * | 1995-02-06 | 1995-02-06 | Astra Ab | New oral pharmaceutical dosage forms |
| SE9500478D0 (sv) * | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
| SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
| CA2400953A1 (en) | 2000-02-24 | 2001-08-30 | Kopran Research Laboratories Limited | Orally administrable acid stable anti-ulcer benzimidazole derivatives |
| SE0101379D0 (sv) | 2001-04-18 | 2001-04-18 | Diabact Ab | Komposition som hämmar utsöndring av magsyra |
| US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
| CA2480826C (fr) | 2002-04-09 | 2012-02-07 | Flamel Technologies | Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s) |
| SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
| EP1708684A2 (en) | 2003-09-26 | 2006-10-11 | Alza Corporation | Drug coating providing high drug loading and methods for providing the same |
| TW200606163A (en) | 2004-04-22 | 2006-02-16 | Eisai Co Ltd | Imidazopyridine compound |
| US8541026B2 (en) | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
| US20070015782A1 (en) * | 2005-04-15 | 2007-01-18 | Eisai Co., Ltd. | Benzimidazole compound |
| US9040564B2 (en) | 2005-04-28 | 2015-05-26 | Eisai R&D Management Co., Ltd. | Stabilized composition |
| US7981908B2 (en) | 2005-05-11 | 2011-07-19 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acid secretion |
| US7803817B2 (en) | 2005-05-11 | 2010-09-28 | Vecta, Ltd. | Composition and methods for inhibiting gastric acid secretion |
| WO2007122686A1 (ja) * | 2006-04-14 | 2007-11-01 | Eisai R & D Management Co., Ltd. | ベンズイミダゾール化合物 |
| CA2658804A1 (en) | 2006-07-25 | 2008-01-31 | Vecta Ltd. | Compositions and methods for inhibiting gastric acid secretion using derivatives of small dicarboxylic acids in combination with ppi |
| EP2065379A4 (en) * | 2006-10-13 | 2011-01-19 | Eisai R&D Man Co Ltd | BENZIMIDAZOLE HAVING INHIBITORY ACTIVITY OF GASTRIC ACID SECRETION |
| CA2736547C (en) | 2008-09-09 | 2016-11-01 | Pozen Inc. | Method for delivering a pharmaceutical composition to patient in need thereof |
| AU2010263304A1 (en) | 2009-06-25 | 2012-02-02 | Astrazeneca Ab | Method for treating a patient at risk for developing an NSAID-associated ulcer |
| WO2011080502A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
| WO2011080500A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
| EP2519229A2 (en) | 2009-12-29 | 2012-11-07 | Novartis AG | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
| EP2601947A1 (en) | 2011-12-05 | 2013-06-12 | Abo Bakr Mohammed Ali Al-Mehdar | Fixed-dose combination for treatment of helicobacter pylori associated diseases |
| UA115139C2 (uk) | 2011-12-28 | 2017-09-25 | Поузен Інк. | Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту |
| CA3036250C (en) * | 2016-09-14 | 2023-09-26 | Yufeng Jane Tseng | Novel substituted benzimidazole derivatives as d-amino acid oxidase (daao) inhibitors |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE418966B (sv) | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
| SE416649B (sv) | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| IN148930B (lv) | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| US4359465A (en) | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
| CH644116A5 (de) | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
| SE8300736D0 (sv) | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| SE8301182D0 (sv) | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
| AU568441B2 (en) * | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
| IL76839A (en) * | 1984-10-31 | 1988-08-31 | Byk Gulden Lomberg Chem Fab | Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
| US4738975A (en) | 1985-07-02 | 1988-04-19 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, and use as anti-ulcer agents |
| SE8505112D0 (sv) * | 1985-10-29 | 1985-10-29 | Haessle Ab | Novel pharmacological compounds |
| NZ222495A (en) | 1986-11-21 | 1991-04-26 | Haessle Ab | Benzimidazole derivatives and pharmaceutical compositions |
| DE3722810A1 (de) * | 1987-07-10 | 1989-01-19 | Hoechst Ag | Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung |
| WO1989003829A1 (en) * | 1987-10-30 | 1989-05-05 | Aktiebolaget Hässle | Omeprazole for treatment of diseases related to bone loss |
| AU2817989A (en) * | 1987-12-11 | 1989-07-05 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel benzimidazole derivatives |
| AU3690289A (en) * | 1988-05-25 | 1989-12-12 | Byk Gulden Lomberg Chemische Fabrik Gmbh | New fluoralkoxy compounds |
-
1990
- 1990-06-20 SE SE9002206A patent/SE9002206D0/xx unknown
-
1991
- 1991-06-05 ZA ZA914297A patent/ZA914297B/xx unknown
- 1991-06-05 ZA ZA914296A patent/ZA914296B/xx unknown
- 1991-06-11 WO PCT/SE1991/000415 patent/WO1991019711A1/en not_active Application Discontinuation
- 1991-06-11 RO RO92-01581A patent/RO110493B1/ro unknown
- 1991-06-11 CA CA002083714A patent/CA2083714A1/en not_active Abandoned
- 1991-06-11 EP EP91911659A patent/EP0535081A1/en not_active Withdrawn
- 1991-06-11 JP JP91511435A patent/JPH05507713A/ja active Pending
- 1991-06-11 AU AU80097/91A patent/AU649453B2/en not_active Ceased
- 1991-06-11 HU HU924033A patent/HUT62881A/hu unknown
- 1991-06-12 TW TW080104582A patent/TW216418B/zh active
- 1991-06-12 YU YU104191A patent/YU104191A/sh unknown
- 1991-06-12 IL IL98470A patent/IL98470A0/xx unknown
- 1991-06-14 IE IE202591A patent/IE912025A1/en unknown
- 1991-06-14 NZ NZ238546A patent/NZ238546A/en unknown
- 1991-06-18 MA MA22462A patent/MA22199A1/fr unknown
- 1991-06-19 PT PT98035A patent/PT98035A/pt not_active Application Discontinuation
- 1991-06-19 TN TNTNSN91049A patent/TNSN91049A1/fr unknown
- 1991-06-19 AP APAP/P/1991/000285A patent/AP215A/en active
- 1991-06-20 CN CN91105024A patent/CN1058212A/zh active Pending
- 1991-06-20 IS IS3721A patent/IS3721A7/is unknown
- 1991-06-20 CZ CS911894A patent/CZ279772B6/cs unknown
-
1992
- 1992-11-27 OA OA60306A patent/OA09682A/en unknown
- 1992-12-10 NO NO924775A patent/NO924775D0/no unknown
- 1992-12-18 FI FI925766A patent/FI925766A/fi not_active Application Discontinuation
- 1992-12-18 BG BG097200A patent/BG97200A/bg unknown
-
1993
- 1993-08-27 LV LV931045A patent/LV10953A/lv unknown
- 1993-12-30 LT LTIP1713A patent/LT3977B/lt not_active IP Right Cessation
- 1993-12-30 LT LTIP1712A patent/LT3952B/lt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AP9100285A0 (en) | 1991-07-31 |
| LT3952B (en) | 1996-05-27 |
| CN1058212A (zh) | 1992-01-29 |
| MA22199A1 (fr) | 1992-04-01 |
| PT98035A (pt) | 1992-03-31 |
| FI925766A0 (fi) | 1992-12-18 |
| SE9002206D0 (sv) | 1990-06-20 |
| IE912025A1 (en) | 1992-01-01 |
| AU649453B2 (en) | 1994-05-26 |
| LTIP1713A (en) | 1995-08-25 |
| BG97200A (bg) | 1993-12-24 |
| LT3977B (en) | 1996-06-25 |
| CZ279772B6 (cs) | 1995-06-14 |
| TNSN91049A1 (fr) | 1992-10-25 |
| HU9204033D0 (en) | 1993-03-29 |
| CS189491A3 (en) | 1992-04-15 |
| AP215A (en) | 1992-09-02 |
| OA09682A (en) | 1993-05-15 |
| NZ238546A (en) | 1994-03-25 |
| WO1991019711A1 (en) | 1991-12-26 |
| IS3721A7 (is) | 1991-12-21 |
| NO924775L (no) | 1992-12-10 |
| ZA914297B (en) | 1992-03-25 |
| NO924775D0 (no) | 1992-12-10 |
| HUT62881A (en) | 1993-06-28 |
| ZA914296B (en) | 1992-03-25 |
| IL98470A0 (en) | 1992-07-15 |
| EP0535081A1 (en) | 1993-04-07 |
| TW216418B (lv) | 1993-11-21 |
| YU104191A (sh) | 1994-01-20 |
| JPH05507713A (ja) | 1993-11-04 |
| FI925766A (fi) | 1992-12-18 |
| LV10953A (lv) | 1995-12-20 |
| LTIP1712A (en) | 1995-08-25 |
| CA2083714A1 (en) | 1991-12-21 |
| AU8009791A (en) | 1992-01-07 |
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