PT99757A - Processo para a preparacao de um sal sulfato de 3-{2-(dimetilamino)-etil}-n-metil-1h-indole-5-metanossulfonamida e de composicoes farmaceuticas que o contem - Google Patents

Processo para a preparacao de um sal sulfato de 3-{2-(dimetilamino)-etil}-n-metil-1h-indole-5-metanossulfonamida e de composicoes farmaceuticas que o contem

Info

Publication number
PT99757A
PT99757A PT99757A PT9975791A PT99757A PT 99757 A PT99757 A PT 99757A PT 99757 A PT99757 A PT 99757A PT 9975791 A PT9975791 A PT 9975791A PT 99757 A PT99757 A PT 99757A
Authority
PT
Portugal
Prior art keywords
methanosulfonamide
indole
dimethylamino
sulfate
ethyl
Prior art date
Application number
PT99757A
Other languages
English (en)
Other versions
PT99757B (pt
Inventor
Joanne Craig
Derek Leslie Crookes
Stephen John Skittrall
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of PT99757A publication Critical patent/PT99757A/pt
Publication of PT99757B publication Critical patent/PT99757B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
PT99757A 1990-12-12 1991-12-11 Processo para a preparacao de um sal sulfato de 3-{2-(dimetilamino)-etil}-n-metil-1h-indole-5-metanossulfonamida e de composicoes farmaceuticas que o contem PT99757B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909026998A GB9026998D0 (en) 1990-12-12 1990-12-12 Medicaments

Publications (2)

Publication Number Publication Date
PT99757A true PT99757A (pt) 1992-12-31
PT99757B PT99757B (pt) 1999-05-31

Family

ID=10686904

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99757A PT99757B (pt) 1990-12-12 1991-12-11 Processo para a preparacao de um sal sulfato de 3-{2-(dimetilamino)-etil}-n-metil-1h-indole-5-metanossulfonamida e de composicoes farmaceuticas que o contem

Country Status (36)

Country Link
US (2) US5554639A (pt)
EP (1) EP0490689B1 (pt)
JP (1) JP2994037B2 (pt)
KR (1) KR100211479B1 (pt)
CN (2) CN1030890C (pt)
AP (1) AP230A (pt)
AT (1) ATE119881T1 (pt)
AU (1) AU650706B2 (pt)
BE (1) BE1005085A3 (pt)
CA (1) CA2098302C (pt)
CH (1) CH684192A5 (pt)
CY (1) CY2005A (pt)
CZ (1) CZ281931B6 (pt)
DE (1) DE69108200T2 (pt)
DK (1) DK0490689T3 (pt)
EG (1) EG20219A (pt)
ES (1) ES2069836T3 (pt)
FR (1) FR2670487B1 (pt)
GB (2) GB9026998D0 (pt)
GR (1) GR3015430T3 (pt)
HK (1) HK82697A (pt)
HU (1) HU211937A9 (pt)
IE (1) IE62894B1 (pt)
IL (1) IL100330A (pt)
IS (1) IS1706B (pt)
IT (1) IT1252868B (pt)
MX (1) MX9102501A (pt)
MY (1) MY109265A (pt)
NL (1) NL9102071A (pt)
NZ (1) NZ240942A (pt)
PT (1) PT99757B (pt)
RU (1) RU2108328C1 (pt)
TW (2) TW300886B (pt)
WO (1) WO1992010477A1 (pt)
YU (1) YU48926B (pt)
ZA (1) ZA919750B (pt)

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MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
KR20080012360A (ko) 2005-05-20 2008-02-11 얀센 파마슈티카 엔.브이. 설파미드 유도체의 제조 방법
US20070166336A1 (en) * 2005-12-13 2007-07-19 David Delmarre Stable and palatable oral liquid sumatriptan compositions
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
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US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
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ES2842523T3 (es) 2015-05-15 2021-07-14 Univ Michigan Regents Métodos y composiciones para el tratamiento de la artritis
JP2019507181A (ja) 2016-03-04 2019-03-14 チャールストン ラボラトリーズ，インコーポレイテッド 医薬組成物
US20180049994A1 (en) 2016-08-16 2018-02-22 Afgin Pharma, Llc Topical regional neuro-affective therapy with caryophyllene
CN117304172A (zh) 2017-11-07 2023-12-29 密执安大学评议会 化合物、药物组合物、其制备方法以及治疗疾病的方法
US20220096438A1 (en) 2018-09-07 2022-03-31 Upsher-Smith Laboratories, Llc Methods of treating migraine
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GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
FR2670487A1 (fr) 1992-06-19
IL100330A0 (en) 1992-09-06
IL100330A (en) 1996-06-18
ZA919750B (en) 1992-10-28
US5554639A (en) 1996-09-10
US5705520A (en) 1998-01-06
BE1005085A3 (fr) 1993-04-13
ES2069836T3 (es) 1995-05-16
AP230A (en) 1993-01-27
NL9102071A (nl) 1992-07-01
DE69108200T2 (de) 1995-07-20
FR2670487B1 (fr) 1993-08-20
IE914317A1 (en) 1992-06-17
CN1063099A (zh) 1992-07-29
KR100211479B1 (ko) 1999-08-02
AU9072091A (en) 1992-07-08
CZ281931B6 (cs) 1997-04-16
CN1050831C (zh) 2000-03-29
GB9026998D0 (en) 1991-01-30
HU211937A9 (en) 1996-01-29
YU191491A (sh) 1994-04-05
AP9100339A0 (en) 1992-01-31
IT1252868B (it) 1995-06-28
JP2994037B2 (ja) 1999-12-27
EG20219A (en) 1997-11-30
WO1992010477A1 (en) 1992-06-25
DE69108200D1 (de) 1995-04-20
CA2098302A1 (en) 1992-06-13
EP0490689B1 (en) 1995-03-15
ITRM910922A1 (it) 1993-06-11
NZ240942A (en) 1994-03-25
PT99757B (pt) 1999-05-31
JPH06503560A (ja) 1994-04-21
HK82697A (en) 1997-06-27
IS1706B (is) 1998-12-10
CH684192A5 (fr) 1994-07-29
CN1128259A (zh) 1996-08-07
IE62894B1 (en) 1995-03-08
DK0490689T3 (da) 1995-05-22
GB2251614B (en) 1994-12-14
GB9126297D0 (en) 1992-02-12
AU650706B2 (en) 1994-06-30
IS3790A7 (is) 1992-06-13
CZ114093A3 (en) 1994-02-16
ATE119881T1 (de) 1995-04-15
EP0490689A1 (en) 1992-06-17
TW300886B (pt) 1997-03-21
CA2098302C (en) 2001-10-16
CY2005A (en) 1997-12-05
YU48926B (sh) 2002-12-10
GB2251614A (en) 1992-07-15
GR3015430T3 (en) 1995-06-30
MX9102501A (es) 1992-09-01
CN1030890C (zh) 1996-02-07
ITRM910922A0 (it) 1991-12-11
RU2108328C1 (ru) 1998-04-10
MY109265A (en) 1996-12-31
TW205035B (pt) 1993-05-01

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