PT99249A - Processo para a preparacao de derivados de piperazina - Google Patents
Processo para a preparacao de derivados de piperazinaInfo
- Publication number
- PT99249A PT99249A PT99249A PT9924991A PT99249A PT 99249 A PT99249 A PT 99249A PT 99249 A PT99249 A PT 99249A PT 9924991 A PT9924991 A PT 9924991A PT 99249 A PT99249 A PT 99249A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- piperazine derivatives
- piperazine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909022790A GB9022790D0 (en) | 1990-10-19 | 1990-10-19 | Piperazine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT99249A true PT99249A (pt) | 1992-08-31 |
| PT99249B PT99249B (pt) | 1999-04-30 |
Family
ID=10684033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99249A PT99249B (pt) | 1990-10-19 | 1991-10-17 | Processo para a preparacao de derivados de piperazina |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5369103A (pt) |
| EP (2) | EP1123926A1 (pt) |
| JP (1) | JP3090683B2 (pt) |
| KR (1) | KR100201192B1 (pt) |
| CA (1) | CA2071940A1 (pt) |
| GB (2) | GB9022790D0 (pt) |
| IE (1) | IE65641B1 (pt) |
| NZ (1) | NZ240273A (pt) |
| PT (1) | PT99249B (pt) |
| WO (1) | WO1992006960A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9125900D0 (en) * | 1991-12-05 | 1992-02-05 | Wyeth John & Brother Ltd | Piperazine derivatives |
| EP0664801A1 (en) * | 1992-08-05 | 1995-08-02 | JOHN WYETH & BROTHER LIMITED | Amide derivatives |
| GB9314758D0 (en) * | 1993-07-16 | 1993-08-25 | Wyeth John & Brother Ltd | Heterocyclic derivatives |
| US5609849A (en) * | 1994-03-11 | 1997-03-11 | The Trustees Of The University Of Pennsylvania | Serotonin (5-HT1A) receptor ligands and imaging agents |
| US5434158A (en) * | 1994-04-26 | 1995-07-18 | Merck & Co., Inc. | Spiro-substituted azacycles as neurokinin-3 antagonists |
| CN101496802B (zh) | 2008-01-31 | 2011-04-27 | 江苏恩华药业股份有限公司 | 芳基哌嗪衍生物在制备治疗疼痛药物方面的用途 |
| EP2611791A4 (en) | 2010-08-12 | 2014-02-12 | Univ New York | OLIGOOXOPIPERAZINES AND METHODS FOR THEIR PREPARATION AND USE |
| JP2016510327A (ja) | 2013-01-19 | 2016-04-07 | ニューヨーク・ユニバーシティ | ｐ５３再活性化のためのオリゴオキソピペラジン |
| US11180481B2 (en) | 2014-04-15 | 2021-11-23 | New York University | Oxopiperazine helix mimetics as inhibitors of the p53-MDM2 interaction |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE630835A (pt) * | 1962-04-16 | |||
| GB2227018B (en) * | 1989-01-13 | 1992-05-20 | Wyeth John & Brother Ltd | Piperazinylalkylcarboxylic acid adamantylamides |
| GB8909209D0 (en) * | 1989-04-22 | 1989-06-07 | Wyeth John & Brother Ltd | Piperazine derivatives |
| HUT54666A (en) * | 1989-04-22 | 1991-03-28 | Wyeth John & Brother Ltd | Process for producing peperazine derivatives and pharmaceutical compositions containing them |
| GB9022821D0 (en) * | 1990-10-19 | 1990-12-05 | Wyeth John & Brother Ltd | Piperazine derivatives |
-
1990
- 1990-10-19 GB GB909022790A patent/GB9022790D0/en active Pending
-
1991
- 1991-10-16 JP JP03516497A patent/JP3090683B2/ja not_active Expired - Fee Related
- 1991-10-16 EP EP01109742A patent/EP1123926A1/en not_active Withdrawn
- 1991-10-16 WO PCT/GB1991/001800 patent/WO1992006960A1/en not_active Application Discontinuation
- 1991-10-16 EP EP91917994A patent/EP0506905A1/en not_active Ceased
- 1991-10-16 GB GB9121945A patent/GB2248837B/en not_active Expired - Fee Related
- 1991-10-16 CA CA002071940A patent/CA2071940A1/en not_active Abandoned
- 1991-10-17 PT PT99249A patent/PT99249B/pt active IP Right Grant
- 1991-10-17 NZ NZ240273A patent/NZ240273A/xx unknown
- 1991-10-18 IE IE366791A patent/IE65641B1/en not_active IP Right Cessation
-
1992
- 1992-06-18 KR KR1019920701441A patent/KR100201192B1/ko not_active IP Right Cessation
- 1992-06-19 US US07/861,834 patent/US5369103A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB9121945D0 (en) | 1991-11-27 |
| NZ240273A (en) | 1992-10-28 |
| PT99249B (pt) | 1999-04-30 |
| EP0506905A1 (en) | 1992-10-07 |
| JPH05502897A (ja) | 1993-05-20 |
| CA2071940A1 (en) | 1992-04-20 |
| WO1992006960A1 (en) | 1992-04-30 |
| GB9022790D0 (en) | 1990-12-05 |
| EP1123926A1 (en) | 2001-08-16 |
| KR927003533A (ko) | 1992-12-18 |
| US5369103A (en) | 1994-11-29 |
| GB2248837A (en) | 1992-04-22 |
| JP3090683B2 (ja) | 2000-09-25 |
| IE913667A1 (en) | 1992-04-22 |
| IE65641B1 (en) | 1995-11-15 |
| GB2248837B (en) | 1994-05-04 |
| KR100201192B1 (ko) | 1999-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920422 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19990107 |