PT92539A - Processo para a preparacao de derivados de anfotericina b - Google Patents

Processo para a preparacao de derivados de anfotericina b

Info

Publication number
PT92539A
PT92539A PT92539A PT9253989A PT92539A PT 92539 A PT92539 A PT 92539A PT 92539 A PT92539 A PT 92539A PT 9253989 A PT9253989 A PT 9253989A PT 92539 A PT92539 A PT 92539A
Authority
PT
Portugal
Prior art keywords
anfotericin
derivatives
preparation
Prior art date
Application number
PT92539A
Other languages
English (en)
Other versions
PT92539B (pt
Inventor
Michael John Driver
Alexander Richard Greenlees
David Timothy Macpherson
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of PT92539A publication Critical patent/PT92539A/pt
Publication of PT92539B publication Critical patent/PT92539B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/08—Polyoxyalkylene derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
PT92539A 1988-12-19 1989-12-11 Processo para a preparacao de derivados de anfotericina b PT92539B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888829592A GB8829592D0 (en) 1988-12-19 1988-12-19 Novel compounds

Publications (2)

Publication Number Publication Date
PT92539A true PT92539A (pt) 1990-06-29
PT92539B PT92539B (pt) 1995-08-09

Family

ID=10648736

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92539A PT92539B (pt) 1988-12-19 1989-12-11 Processo para a preparacao de derivados de anfotericina b

Country Status (11)

Country Link
US (1) US5066646A (pt)
EP (1) EP0375223A3 (pt)
JP (1) JPH02207094A (pt)
KR (1) KR900009678A (pt)
AU (1) AU614205B2 (pt)
CA (1) CA2005133A1 (pt)
DK (1) DK625389A (pt)
GB (1) GB8829592D0 (pt)
NZ (1) NZ231723A (pt)
PT (1) PT92539B (pt)
ZA (1) ZA899505B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0350164A3 (en) * 1988-06-13 1991-07-24 Beecham Group Plc Amphotericin derivatives
GB8829593D0 (en) * 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds
WO1991009047A1 (en) * 1989-12-08 1991-06-27 Beecham Group Plc Amphotericin b derivatives, their production and use
GB9114949D0 (en) * 1991-07-11 1991-08-28 Smithkline Beecham Plc Novel compounds
FR2683723B1 (fr) * 1991-11-14 1995-05-19 Mayoly Spindler Laboratoires Nouveaux medicaments antiviraux actifs sur le virus vih.
GB9200713D0 (en) * 1992-01-14 1992-03-11 Smithkline Beecham Plc Novel compounds
GB9203476D0 (en) * 1992-02-19 1992-04-08 Smithkline Beecham Plc Novel compounds
EP1278527A4 (en) 2000-01-14 2003-04-09 Intrabiotics Pharmaceuticals DERIVATIVES OF POLYEN MACROLIDES, THEIR PRODUCTION AND USE
CN102115484B (zh) * 2009-12-31 2013-03-13 中国药品生物制品检定所 一种两性霉素b降解产物、其制备方法及其应用
WO2013132014A1 (en) 2012-03-09 2013-09-12 Blirt S.A. Semisynthetic derivatives of nystatin a1
JP2015519389A (ja) 2012-06-15 2015-07-09 ブリート スポルカ アクシヤ 抗真菌性抗生物質アンフォテリシンｂのｎ−置換第二世代誘導体ならびにそれらの調製および塗布方法
CA3021061C (en) 2015-04-15 2023-10-24 Martin D. Burke Derivatives of amphotericin b
TWI637980B (zh) * 2017-01-11 2018-10-11 長興材料工業股份有限公司 聚醯亞胺前驅物及其應用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2173632A1 (en) * 1971-02-04 1973-10-12 Le N Iss Purificn of amfotericin b - in dmf soln by adding water acidifying filtering adding water,making alkaline and washing
US4041232A (en) * 1976-02-23 1977-08-09 E. R. Squibb & Sons, Inc. Amphotericin B methyl ester salts
US4235993A (en) * 1979-02-21 1980-11-25 E. R. Squibb & Sons, Inc. N-Benzylideneamphotericin B, its methyl ester and process for making water-soluble salts thereof
EP0350164A3 (en) * 1988-06-13 1991-07-24 Beecham Group Plc Amphotericin derivatives
GB8829593D0 (en) * 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
NZ231723A (en) 1992-03-26
US5066646A (en) 1991-11-19
GB8829592D0 (en) 1989-02-08
KR900009678A (ko) 1990-07-05
AU4617189A (en) 1990-06-21
DK625389A (da) 1990-06-20
CA2005133A1 (en) 1990-06-19
ZA899505B (en) 1990-12-28
EP0375223A2 (en) 1990-06-27
EP0375223A3 (en) 1991-07-03
JPH02207094A (ja) 1990-08-16
DK625389D0 (da) 1989-12-11
PT92539B (pt) 1995-08-09
AU614205B2 (en) 1991-08-22

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19950412

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19961031