PT90266A - Processo para a preparacao de compostos azabiciclicos - Google Patents

Processo para a preparacao de compostos azabiciclicos

Info

Publication number
PT90266A
PT90266A PT90266A PT9026689A PT90266A PT 90266 A PT90266 A PT 90266A PT 90266 A PT90266 A PT 90266A PT 9026689 A PT9026689 A PT 9026689A PT 90266 A PT90266 A PT 90266A
Authority
PT
Portugal
Prior art keywords
preparation
azabicylic
compounds
azabicylic compounds
Prior art date
Application number
PT90266A
Other languages
English (en)
Other versions
PT90266B (pt
Inventor
Michael Stewart Hadley
Barry Sidney Orlek
Steven Mark Bromidge
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888808925A external-priority patent/GB8808925D0/en
Priority claimed from GB888812602A external-priority patent/GB8812602D0/en
Priority claimed from GB888824076A external-priority patent/GB8824076D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of PT90266A publication Critical patent/PT90266A/pt
Publication of PT90266B publication Critical patent/PT90266B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT90266A 1988-04-15 1989-04-13 Processo para a preparacao de compostos azabiciclicos PT90266B (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888808925A GB8808925D0 (en) 1988-04-15 1988-04-15 Novel compounds
GB888812602A GB8812602D0 (en) 1988-05-27 1988-05-27 Novel compounds
GB888824076A GB8824076D0 (en) 1988-10-13 1988-10-13 Novel compounds

Publications (2)

Publication Number Publication Date
PT90266A true PT90266A (pt) 1989-11-10
PT90266B PT90266B (pt) 1994-07-29

Family

ID=27263861

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90266A PT90266B (pt) 1988-04-15 1989-04-13 Processo para a preparacao de compostos azabiciclicos

Country Status (8)

Country Link
US (1) US5110828A (pt)
EP (1) EP0338723B1 (pt)
JP (1) JP2917224B2 (pt)
KR (1) KR900016203A (pt)
AU (1) AU3301689A (pt)
DE (1) DE68907982T2 (pt)
DK (1) DK177889A (pt)
PT (1) PT90266B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1227436B (it) * 1988-10-28 1991-04-11 Roussel Maestretti Spa Derivati di 1-azabicicloalcani, loro procedimento di preparazione e loro applicazione come farmaci
US5183893A (en) * 1988-10-28 1993-02-02 Roussel Uclaf 1-azabicycloalkane derivatives, their preparation process and their use as medicaments
US4937239A (en) * 1989-02-13 1990-06-26 Warner-Lambert Company Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents
EP0392803B1 (en) * 1989-04-13 2004-06-16 Beecham Group p.l.c. Novel compounds
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
EP0413545B1 (en) * 1989-08-16 1997-05-14 Beecham Group Plc Azabicyclic compounds
JPH06500550A (ja) * 1990-08-24 1994-01-20 ビーチャム・グループ・パブリック・リミテッド・カンパニー アザ二環式化合物、その製造方法および製造用中間体ならびにその化合物含有の医薬組成物
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
JPH06501933A (ja) * 1990-10-12 1994-03-03 ビーチャム・グループ・パブリック・リミテッド・カンパニー １，２，５，６−テトラヒドロピリジン・オキシム誘導体
WO1993008191A1 (en) * 1991-10-15 1993-04-29 Warner-Lambert Company Azabicyclo oxime and amine cholinergic agents and methods of treatment
US5190953A (en) * 1992-03-26 1993-03-02 A. H. Robins Company, Incorporated Heterocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
US5244907A (en) * 1992-03-26 1993-09-14 A. H. Robins Company, Incorporated Carbocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
IT1255179B (it) * 1992-06-26 1995-10-20 Enzo Cereda Azaciclo e azabiciclo alchiliden idrossilamine
US5936088A (en) * 1995-09-22 1999-08-10 Novo Nordisk A/S Substituted azacyclic or azabicyclic compounds with affinity and selectivity for nicotinic cholinergic receptors
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
EP2068872A1 (en) 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU563225B2 (en) * 1982-04-14 1987-07-02 Alizyme Therapeutics Limited I-aza bicyclic compounds
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
GB8615785D0 (en) * 1986-06-27 1986-08-06 Beecham Group Plc Compounds
DE3789039T2 (de) * 1986-06-27 1994-06-09 Beecham Group Plc Verbrückte bicyclische N-heterocyclische Verbindungen.
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4798841A (en) * 1987-03-31 1989-01-17 Warner-Lambert Company Tetrahydropyridine oxime cholinergic agents and method of treatment
AU614513B2 (en) * 1987-04-15 1991-09-05 Beecham Group Plc 1-azabicyclic compounds
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti
IT1222526B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
IT1222529B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropirdin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
IT1233446B (it) * 1987-12-30 1992-04-01 Roussel Maestretti Spa Derivati della 3 piperidinocarbaldeide ossima, loro procedimento di preparazione e loro applicazione come farmaci
US4937239A (en) * 1989-02-13 1990-06-26 Warner-Lambert Company Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents

Also Published As

Publication number Publication date
DK177889D0 (da) 1989-04-13
DE68907982T2 (de) 1994-01-20
EP0338723A1 (en) 1989-10-25
US5110828A (en) 1992-05-05
JP2917224B2 (ja) 1999-07-12
EP0338723B1 (en) 1993-08-04
DK177889A (da) 1989-10-16
KR900016203A (ko) 1990-11-12
PT90266B (pt) 1994-07-29
DE68907982D1 (de) 1993-09-09
JPH01316376A (ja) 1989-12-21
AU3301689A (en) 1989-10-26

Similar Documents

Publication Publication Date Title
PT92534A (pt) Processo para a preparacao de compostos azabiciclicos
PT90619A (pt) Processo para a preparacao de compostos de piperazina
PT91068A (pt) Processo para a preparacao de compostos biarilo
PT90119A (pt) Processo para a preparacao de um adocante
PT90293A (pt) Processo para a preparacao de macrolidos
PT89264A (pt) Processo para a preparacao de compostos azabiciclicos
PT91895A (pt) Processo para a preparacao de 9h-purinas substituidas
PT91183A (pt) Processo para a preparacao de composicoes fungicidas
PT92786A (pt) Processo para a preparacao de compostos de tiazol
PT91872A (pt) Processo para a preparacao de compostos azabiciclicos
BR8906327A (pt) Processo para a preparacao de organoclorossilanos
PT90266A (pt) Processo para a preparacao de compostos azabiciclicos
PT90854A (pt) Processo para a preparacao de 1-aril-2-naftoilaminas
PT92638A (pt) Processo para a preparacao de poliazamacrociclos mono-n-alquilados
PT92365A (pt) Processo para a preparacao de (s)-alfa-etil-2-oxo-1-pirrolidinoacetamida
BR9001503A (pt) Processo para a preparacao de alquil-halogenossilanos
PT89775A (pt) Processo para a preparacao de derivados de isoquinolina
PT91027A (pt) Processo para a preparacao de derivados peptidicos
PT92539A (pt) Processo para a preparacao de derivados de anfotericina b
BR8903367A (pt) Processo para a preparacao de organoclorossilanos
PT90830A (pt) Processo para a preparacao de compostos macrolidos polienicos
BR8902030A (pt) Processo para a preparacao de n-fosfonometilglicina
PT94890A (pt) Processo para a preparacao de compostos azofenilicos
PT91401A (pt) Processo para a preparacao de compostos de benzodiazepina
PT92507A (pt) Processo para a preparacao de alfa-ciano-beta-oxopropionamidas

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940110