PT91895A - Processo para a preparacao de 9h-purinas substituidas - Google Patents

Processo para a preparacao de 9h-purinas substituidas

Info

Publication number
PT91895A
PT91895A PT91895A PT9189589A PT91895A PT 91895 A PT91895 A PT 91895A PT 91895 A PT91895 A PT 91895A PT 9189589 A PT9189589 A PT 9189589A PT 91895 A PT91895 A PT 91895A
Authority
PT
Portugal
Prior art keywords
purins
replaced
preparation
Prior art date
Application number
PT91895A
Other languages
English (en)
Other versions
PT91895B (pt
Inventor
Hans Allgeier
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PT91895A publication Critical patent/PT91895A/pt
Publication of PT91895B publication Critical patent/PT91895B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT91895A 1988-10-06 1989-10-04 Processo para a preparacao de 9h-purinas substituidas PT91895B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH373188 1988-10-06

Publications (2)

Publication Number Publication Date
PT91895A true PT91895A (pt) 1990-04-30
PT91895B PT91895B (pt) 1995-05-31

Family

ID=4262288

Family Applications (1)

Application Number Title Priority Date Filing Date
PT91895A PT91895B (pt) 1988-10-06 1989-10-04 Processo para a preparacao de 9h-purinas substituidas

Country Status (17)

Country Link
US (1) US5110818A (pt)
EP (1) EP0363320A3 (pt)
JP (1) JPH02157279A (pt)
KR (1) KR900006337A (pt)
AU (1) AU632763B2 (pt)
CA (1) CA2000154A1 (pt)
DD (1) DD297820A5 (pt)
DK (1) DK491389A (pt)
FI (1) FI894707A (pt)
HU (1) HUT52502A (pt)
IL (1) IL91818A (pt)
MX (1) MX17846A (pt)
NO (1) NO172986C (pt)
NZ (1) NZ230898A (pt)
PH (1) PH27154A (pt)
PT (1) PT91895B (pt)
ZA (1) ZA897587B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391739A (en) * 1989-03-29 1995-02-21 Merrell Dow Pharmaceuticals Inc. Selective adenosine receptor agents
US5387684A (en) * 1992-03-25 1995-02-07 The Green Cross Corporation Isoindazole compound
FR2699176B1 (fr) * 1992-12-11 1995-03-03 Adir Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5994361A (en) * 1994-06-22 1999-11-30 Biochem Pharma Substituted purinyl derivatives with immunomodulating activity
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
DE19535504A1 (de) * 1995-09-25 1997-03-27 Bayer Ag Substituierte Xanthine
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
FR2741881B1 (fr) * 1995-12-01 1999-07-30 Centre Nat Rech Scient Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US6294541B1 (en) 1996-06-06 2001-09-25 Euro-Celtique S.A. Purine derivatives having phosphodiesterase IV inhibition activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US6413975B1 (en) 1999-04-02 2002-07-02 Euro-Celtique, S.A. Purine derivatives having phosphodiesterase iv inhibition activity
US6057445A (en) 1997-12-12 2000-05-02 Euro-Celtique S.A. Purine compounds having PDE IV inhibitory activity and methods of synthesis
US6319928B1 (en) 1998-11-30 2001-11-20 Euro-Celtique, S.A. Purine derivatives having phosphodiesterase IV inhibition activity
CA2426952C (en) * 2000-11-02 2012-06-26 Sloan-Kettering Institute For Cancer Research Small molecule compositions for binding to hsp90
EP2336133A1 (en) * 2001-10-30 2011-06-22 Conforma Therapeutics Corporation Purine analogs having HSP90-inhibiting activity
US20070129334A1 (en) * 2001-10-30 2007-06-07 Conforma Therapeutics Corporation Orally Active Purine-Based Inhibitors of Heat Shock Protein 90
BRPI0414533A (pt) * 2003-09-18 2006-11-07 Conforma Therapeutics Corp composto, composição farmacêutica, e, métodos para inibir um hsp90 e para tratar um indivìduo tendo um distúrbio mediado por hsp90
CA2602257A1 (en) * 2005-03-30 2006-10-05 Conforma Therapeutics Corporation Alkynyl pyrrolopyrimidines and related analogs as hsp90-inhibitors
US20070105874A1 (en) * 2005-09-23 2007-05-10 Conforma Therapeutics Corporation Anti-Tumor Methods Using Multi Drug Resistance Independent Synthetic HSP90 Inhibitors
WO2009034386A1 (en) * 2007-09-13 2009-03-19 Astrazeneca Ab Derivatives of adenine and 8-aza-adenine and uses thereof-796

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846426A (en) * 1971-03-03 1974-11-05 Int Minerals & Chem Corp 6-amino-9-(substituted benzyl) purines and their n{11 oxides
GB1534163A (en) * 1976-07-28 1978-11-29 Merck & Co Inc Adenine derivatives
USRE31429E (en) * 1977-02-14 1983-10-25 Merck & Co., Inc. Process for preparation of 9-(dihalobenzyl)adenines
GB1547214A (en) * 1977-08-09 1979-06-06 Merck & Co Inc Purine derivatives
US4189485A (en) * 1977-08-23 1980-02-19 Takeda Chemical Industries, Ltd. Purine derivatives
US4361699A (en) * 1981-09-28 1982-11-30 Merck & Co., Inc. Novel process for the preparation of N6 -alkyl-arprinocid
AU573540B2 (en) * 1982-10-14 1988-06-16 Wellcome Foundation Limited, The 6-hydrogen purine derivatives
US4748177A (en) * 1984-03-26 1988-05-31 Warner-Lambert Company Guanine derivatives
GB8408615D0 (en) * 1984-04-04 1984-05-16 Wellcome Found Heterocyclic compounds
KR910700253A (ko) * 1989-01-31 1991-03-14 로버트 제이, 바란 N_6-치환-9-메틸아데닌: 신규한 부류의 아데노신 수용체 길항질

Also Published As

Publication number Publication date
EP0363320A3 (de) 1991-11-21
NO172986B (no) 1993-06-28
NO893965D0 (no) 1989-10-05
NO893965L (no) 1990-04-09
NO172986C (no) 1993-10-06
MX17846A (es) 1994-03-31
PH27154A (en) 1993-04-02
AU632763B2 (en) 1993-01-14
NZ230898A (en) 1992-12-23
AU4261289A (en) 1990-04-12
JPH02157279A (ja) 1990-06-18
IL91818A (en) 1994-08-26
KR900006337A (ko) 1990-05-07
HUT52502A (en) 1990-07-28
DK491389A (da) 1990-04-07
DK491389D0 (da) 1989-10-05
US5110818A (en) 1992-05-05
EP0363320A2 (de) 1990-04-11
IL91818A0 (en) 1990-06-10
DD297820A5 (de) 1992-01-23
ZA897587B (en) 1990-05-30
FI894707A0 (fi) 1989-10-04
CA2000154A1 (en) 1990-04-06
PT91895B (pt) 1995-05-31
FI894707A (fi) 1990-04-07

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19941121

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960531