NO172986C - Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte 9h-puriner - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte 9h-puriner

Info

Publication number
NO172986C
NO172986C NO893965A NO893965A NO172986C NO 172986 C NO172986 C NO 172986C NO 893965 A NO893965 A NO 893965A NO 893965 A NO893965 A NO 893965A NO 172986 C NO172986 C NO 172986C
Authority
NO
Norway
Prior art keywords
purines
preparation
therapeutic active
active substituted
analogue procedure
Prior art date
Application number
NO893965A
Other languages
English (en)
Other versions
NO172986B (no
NO893965D0 (no
NO893965L (no
Inventor
Hans Allgeier
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO893965D0 publication Critical patent/NO893965D0/no
Publication of NO893965L publication Critical patent/NO893965L/no
Publication of NO172986B publication Critical patent/NO172986B/no
Publication of NO172986C publication Critical patent/NO172986C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO893965A 1988-10-06 1989-10-05 Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte 9h-puriner NO172986C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH373188 1988-10-06

Publications (4)

Publication Number Publication Date
NO893965D0 NO893965D0 (no) 1989-10-05
NO893965L NO893965L (no) 1990-04-09
NO172986B NO172986B (no) 1993-06-28
NO172986C true NO172986C (no) 1993-10-06

Family

ID=4262288

Family Applications (1)

Application Number Title Priority Date Filing Date
NO893965A NO172986C (no) 1988-10-06 1989-10-05 Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte 9h-puriner

Country Status (17)

Country Link
US (1) US5110818A (no)
EP (1) EP0363320A3 (no)
JP (1) JPH02157279A (no)
KR (1) KR900006337A (no)
AU (1) AU632763B2 (no)
CA (1) CA2000154A1 (no)
DD (1) DD297820A5 (no)
DK (1) DK491389A (no)
FI (1) FI894707A7 (no)
HU (1) HUT52502A (no)
IL (1) IL91818A (no)
MX (1) MX17846A (no)
NO (1) NO172986C (no)
NZ (1) NZ230898A (no)
PH (1) PH27154A (no)
PT (1) PT91895B (no)
ZA (1) ZA897587B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391739A (en) * 1989-03-29 1995-02-21 Merrell Dow Pharmaceuticals Inc. Selective adenosine receptor agents
US5387684A (en) * 1992-03-25 1995-02-07 The Green Cross Corporation Isoindazole compound
FR2699176B1 (fr) * 1992-12-11 1995-03-03 Adir Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US6110923A (en) * 1994-06-22 2000-08-29 Biochem Pharma Inc. Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
DE19535504A1 (de) * 1995-09-25 1997-03-27 Bayer Ag Substituierte Xanthine
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
FR2741881B1 (fr) * 1995-12-01 1999-07-30 Centre Nat Rech Scient Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) * 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US6294541B1 (en) 1996-06-06 2001-09-25 Euro-Celtique S.A. Purine derivatives having phosphodiesterase IV inhibition activity
HUP0301166A2 (en) 1997-12-12 2003-08-28 Euro Celtique Sa 3-substituted adenines via2-thioxanthines
US6319928B1 (en) 1998-11-30 2001-11-20 Euro-Celtique, S.A. Purine derivatives having phosphodiesterase IV inhibition activity
KR20020065341A (ko) 1999-04-02 2002-08-13 유로-셀티크 소시에떼 아노뉨 포스포디에스트라스(phosphodiesterase, PDE) Ⅳ 억제작용을 가진 푸린 유도체
JP2005519848A (ja) * 2000-11-02 2005-07-07 スローン−ケッタリング・インスティテュート・フォー・キャンサー・リサーチ Ｈｓｐ９０に結合するための小分子組成物
US20070129334A1 (en) * 2001-10-30 2007-06-07 Conforma Therapeutics Corporation Orally Active Purine-Based Inhibitors of Heat Shock Protein 90
EP2336133A1 (en) 2001-10-30 2011-06-22 Conforma Therapeutics Corporation Purine analogs having HSP90-inhibiting activity
EP2145888A1 (en) * 2003-09-18 2010-01-20 Conforma Therapeutics Corporation Deazapurine derivatives as HSP90-Inhibitors
BRPI0609509A2 (pt) * 2005-03-30 2010-04-13 Conforma Therapeutics Corp composto ou um polimorfo, solvato, tautÈmero, enanciÈmero, pró-droga ou sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso do composto, polimorfo, solvato, tautÈmero, enanciÈmero, pró-droga ou sal farmaceuticamente aceitável
US20070105874A1 (en) * 2005-09-23 2007-05-10 Conforma Therapeutics Corporation Anti-Tumor Methods Using Multi Drug Resistance Independent Synthetic HSP90 Inhibitors
WO2009034386A1 (en) * 2007-09-13 2009-03-19 Astrazeneca Ab Derivatives of adenine and 8-aza-adenine and uses thereof-796

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846426A (en) * 1971-03-03 1974-11-05 Int Minerals & Chem Corp 6-amino-9-(substituted benzyl) purines and their n{11 oxides
GB1534163A (en) * 1976-07-28 1978-11-29 Merck & Co Inc Adenine derivatives
USRE31429E (en) * 1977-02-14 1983-10-25 Merck & Co., Inc. Process for preparation of 9-(dihalobenzyl)adenines
GB1547214A (en) * 1977-08-09 1979-06-06 Merck & Co Inc Purine derivatives
US4189485A (en) * 1977-08-23 1980-02-19 Takeda Chemical Industries, Ltd. Purine derivatives
US4361699A (en) * 1981-09-28 1982-11-30 Merck & Co., Inc. Novel process for the preparation of N6 -alkyl-arprinocid
NZ205955A (en) * 1982-10-14 1988-02-29 Wellcome Found 2-amino-9-(2-hydroxyethoxymethyl)-9h-purine
US4748177A (en) * 1984-03-26 1988-05-31 Warner-Lambert Company Guanine derivatives
GB8408615D0 (en) * 1984-04-04 1984-05-16 Wellcome Found Heterocyclic compounds
KR910700253A (ko) * 1989-01-31 1991-03-14 로버트 제이, 바란 N_6-치환-9-메틸아데닌: 신규한 부류의 아데노신 수용체 길항질

Also Published As

Publication number Publication date
EP0363320A2 (de) 1990-04-11
US5110818A (en) 1992-05-05
NO172986B (no) 1993-06-28
MX17846A (es) 1994-03-31
DK491389A (da) 1990-04-07
DD297820A5 (de) 1992-01-23
IL91818A (en) 1994-08-26
PT91895B (pt) 1995-05-31
AU4261289A (en) 1990-04-12
KR900006337A (ko) 1990-05-07
JPH02157279A (ja) 1990-06-18
NO893965D0 (no) 1989-10-05
DK491389D0 (da) 1989-10-05
ZA897587B (en) 1990-05-30
NZ230898A (en) 1992-12-23
HUT52502A (en) 1990-07-28
FI894707A7 (fi) 1990-04-07
AU632763B2 (en) 1993-01-14
PH27154A (en) 1993-04-02
EP0363320A3 (de) 1991-11-21
FI894707A0 (fi) 1989-10-04
CA2000154A1 (en) 1990-04-06
NO893965L (no) 1990-04-09
IL91818A0 (en) 1990-06-10
PT91895A (pt) 1990-04-30

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