PT91895A - PROCESS FOR THE PREPARATION OF REPLACED 9H-PURINS - Google Patents

PROCESS FOR THE PREPARATION OF REPLACED 9H-PURINS

Info

Publication number
PT91895A
PT91895A PT91895A PT9189589A PT91895A PT 91895 A PT91895 A PT 91895A PT 91895 A PT91895 A PT 91895A PT 9189589 A PT9189589 A PT 9189589A PT 91895 A PT91895 A PT 91895A
Authority
PT
Portugal
Prior art keywords
purins
replaced
preparation
Prior art date
Application number
PT91895A
Other languages
Portuguese (pt)
Other versions
PT91895B (en
Inventor
Hans Allgeier
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PT91895A publication Critical patent/PT91895A/en
Publication of PT91895B publication Critical patent/PT91895B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
PT91895A 1988-10-06 1989-10-04 PROCESS FOR THE PREPARATION OF REPLACED 9H-PURINS PT91895B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH373188 1988-10-06

Publications (2)

Publication Number Publication Date
PT91895A true PT91895A (en) 1990-04-30
PT91895B PT91895B (en) 1995-05-31

Family

ID=4262288

Family Applications (1)

Application Number Title Priority Date Filing Date
PT91895A PT91895B (en) 1988-10-06 1989-10-04 PROCESS FOR THE PREPARATION OF REPLACED 9H-PURINS

Country Status (17)

Country Link
US (1) US5110818A (en)
EP (1) EP0363320A3 (en)
JP (1) JPH02157279A (en)
KR (1) KR900006337A (en)
AU (1) AU632763B2 (en)
CA (1) CA2000154A1 (en)
DD (1) DD297820A5 (en)
DK (1) DK491389A (en)
FI (1) FI894707A (en)
HU (1) HUT52502A (en)
IL (1) IL91818A (en)
MX (1) MX17846A (en)
NO (1) NO172986C (en)
NZ (1) NZ230898A (en)
PH (1) PH27154A (en)
PT (1) PT91895B (en)
ZA (1) ZA897587B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391739A (en) * 1989-03-29 1995-02-21 Merrell Dow Pharmaceuticals Inc. Selective adenosine receptor agents
US5387684A (en) * 1992-03-25 1995-02-07 The Green Cross Corporation Isoindazole compound
FR2699176B1 (en) * 1992-12-11 1995-03-03 Adir New bicyclic pyrimidine compounds, process for their preparation and pharmaceutical compositions containing them.
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5994361A (en) * 1994-06-22 1999-11-30 Biochem Pharma Substituted purinyl derivatives with immunomodulating activity
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
DE19535504A1 (en) * 1995-09-25 1997-03-27 Bayer Ag Substituted xanthines
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
FR2741881B1 (en) * 1995-12-01 1999-07-30 Centre Nat Rech Scient NOVEL PURINE DERIVATIVES HAVING IN PARTICULAR ANTI-PROLIFERATIVE PRORIETES AND THEIR BIOLOGICAL APPLICATIONS
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US6294541B1 (en) 1996-06-06 2001-09-25 Euro-Celtique S.A. Purine derivatives having phosphodiesterase IV inhibition activity
CN1294590A (en) 1997-12-12 2001-05-09 欧罗赛铁克股份有限公司 Method of 3-substituted adenines via 2-thioxanthines
US6319928B1 (en) 1998-11-30 2001-11-20 Euro-Celtique, S.A. Purine derivatives having phosphodiesterase IV inhibition activity
AR029347A1 (en) 1999-04-02 2003-06-25 Euro Celtique Sa ADENINE COMPOUND, ISOGNANINE COMPOUND AND 2,6-DITIOXANTINE AS A PRECURSOR OF THE SAME, USE OF SUCH COMPOUNDS TO PREPARE A PHARMACEUTICAL COMPOSITION AND SUCH PHARMACEUTICAL COMPOSITION
US7439359B2 (en) * 2000-11-02 2008-10-21 Sloan-Kettering Institute For Cancer Research Small molecule compositions for binding to hsp90
EP1440072A4 (en) * 2001-10-30 2005-02-02 Conforma Therapeutic Corp Purine analogs having hsp90-inhibiting activity
US20070129334A1 (en) * 2001-10-30 2007-06-07 Conforma Therapeutics Corporation Orally Active Purine-Based Inhibitors of Heat Shock Protein 90
JP2007505933A (en) 2003-09-18 2007-03-15 コンフォーマ・セラピューティクス・コーポレイション Novel heterocyclic compounds as HSP90 inhibitors
JP2008534609A (en) * 2005-03-30 2008-08-28 コンフォーマ・セラピューティクス・コーポレイション Alkynylpyrrolopyrimidines and related analogs as HSP90 inhibitors
EP1937258A2 (en) * 2005-09-23 2008-07-02 Conforma Therapeutics Corporation Anti-tumor methods using multi drug resistance independent synthetic hsp90 inhibitors
WO2009034386A1 (en) * 2007-09-13 2009-03-19 Astrazeneca Ab Derivatives of adenine and 8-aza-adenine and uses thereof-796

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846426A (en) * 1971-03-03 1974-11-05 Int Minerals & Chem Corp 6-amino-9-(substituted benzyl) purines and their n{11 oxides
GB1534163A (en) * 1976-07-28 1978-11-29 Merck & Co Inc Adenine derivatives
USRE31429E (en) * 1977-02-14 1983-10-25 Merck & Co., Inc. Process for preparation of 9-(dihalobenzyl)adenines
GB1547214A (en) * 1977-08-09 1979-06-06 Merck & Co Inc Purine derivatives
US4189485A (en) * 1977-08-23 1980-02-19 Takeda Chemical Industries, Ltd. Purine derivatives
US4361699A (en) * 1981-09-28 1982-11-30 Merck & Co., Inc. Novel process for the preparation of N6 -alkyl-arprinocid
ZW22283A1 (en) * 1982-10-14 1985-05-22 Wellcome Found Antiviral compounds
US4748177A (en) * 1984-03-26 1988-05-31 Warner-Lambert Company Guanine derivatives
GB8408615D0 (en) * 1984-04-04 1984-05-16 Wellcome Found Heterocyclic compounds
AU626983B2 (en) * 1989-01-31 1992-08-13 Whitby Research, Inc. N6-substituted 9-methyladenines

Also Published As

Publication number Publication date
EP0363320A2 (en) 1990-04-11
NO172986C (en) 1993-10-06
KR900006337A (en) 1990-05-07
HUT52502A (en) 1990-07-28
NO893965D0 (en) 1989-10-05
AU632763B2 (en) 1993-01-14
AU4261289A (en) 1990-04-12
DK491389D0 (en) 1989-10-05
CA2000154A1 (en) 1990-04-06
MX17846A (en) 1994-03-31
JPH02157279A (en) 1990-06-18
NO893965L (en) 1990-04-09
US5110818A (en) 1992-05-05
NZ230898A (en) 1992-12-23
FI894707A (en) 1990-04-07
IL91818A0 (en) 1990-06-10
DD297820A5 (en) 1992-01-23
EP0363320A3 (en) 1991-11-21
NO172986B (en) 1993-06-28
PT91895B (en) 1995-05-31
ZA897587B (en) 1990-05-30
DK491389A (en) 1990-04-07
PH27154A (en) 1993-04-02
IL91818A (en) 1994-08-26
FI894707A0 (en) 1989-10-04

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19941121

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960531