PT991640E - Sintese de intermediarios uteis na preparacao de compostos triciclicos substituidos por bromo - Google Patents
Sintese de intermediarios uteis na preparacao de compostos triciclicos substituidos por bromoInfo
- Publication number
- PT991640E PT991640E PT98928873T PT98928873T PT991640E PT 991640 E PT991640 E PT 991640E PT 98928873 T PT98928873 T PT 98928873T PT 98928873 T PT98928873 T PT 98928873T PT 991640 E PT991640 E PT 991640E
- Authority
- PT
- Portugal
- Prior art keywords
- uteric
- intermediaries
- bromo
- synthesis
- preparation
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 125000001246 bromo group Chemical class Br* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/882,753 US5760232A (en) | 1997-06-16 | 1997-06-16 | Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT991640E true PT991640E (pt) | 2002-07-31 |
Family
ID=25381267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98928873T PT991640E (pt) | 1997-06-16 | 1998-06-15 | Sintese de intermediarios uteis na preparacao de compostos triciclicos substituidos por bromo |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5760232A (enExample) |
| EP (1) | EP0991640B1 (enExample) |
| JP (1) | JP3210023B2 (enExample) |
| AR (1) | AR015886A1 (enExample) |
| AT (1) | ATE214062T1 (enExample) |
| AU (1) | AU8056898A (enExample) |
| CA (1) | CA2293709C (enExample) |
| DE (1) | DE69804100T2 (enExample) |
| DK (1) | DK0991640T3 (enExample) |
| ES (1) | ES2169917T3 (enExample) |
| IN (1) | IN187755B (enExample) |
| MY (1) | MY133531A (enExample) |
| PT (1) | PT991640E (enExample) |
| WO (1) | WO1998057958A1 (enExample) |
| ZA (1) | ZA985207B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5998620A (en) * | 1997-03-25 | 1999-12-07 | Schering Corporation | Synthesis of intermediates useful in preparing tricyclic compounds |
| PT1556358E (pt) * | 2002-10-03 | 2007-09-25 | Schering Corp | ''alquilação enantiosselectiva de compostos tricíclicos'' |
| PL2797416T3 (pl) | 2011-12-28 | 2017-12-29 | Global Blood Therapeutics, Inc. | Podstawione związki benzaldehydowe i sposoby ich zastosowania do zwiększania natlenienia tkanek |
| US9012450B2 (en) | 2011-12-28 | 2015-04-21 | Global Blood Therapeutics, Inc. | Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation |
| BR112015021982B1 (pt) | 2013-03-15 | 2022-12-13 | Global Blood Therapeutics, Inc | Compostos e seus usos para a modulação de hemoglobina |
| US20140274961A1 (en) | 2013-03-15 | 2014-09-18 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US10266551B2 (en) | 2013-03-15 | 2019-04-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9802900B2 (en) | 2013-03-15 | 2017-10-31 | Global Blood Therapeutics, Inc. | Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin |
| US9422279B2 (en) | 2013-03-15 | 2016-08-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9604999B2 (en) | 2013-03-15 | 2017-03-28 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9458139B2 (en) | 2013-03-15 | 2016-10-04 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| WO2014145040A1 (en) | 2013-03-15 | 2014-09-18 | Global Blood Therapeutics, Inc. | Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation |
| EP2968299B1 (en) | 2013-03-15 | 2021-01-20 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| JP6426694B2 (ja) | 2013-03-15 | 2018-11-21 | グローバル ブラッド セラピューティクス インコーポレイテッド | ヘモグロビンの修飾のための化合物及びその使用 |
| EA201992707A1 (ru) | 2013-11-18 | 2020-06-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
| AP2016009261A0 (en) | 2014-02-07 | 2016-06-30 | Global Blood Therapeutics Inc | Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde |
| MA41841A (fr) | 2015-03-30 | 2018-02-06 | Global Blood Therapeutics Inc | Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs |
| PL3383392T3 (pl) | 2015-12-04 | 2025-11-17 | Global Blood Therapeutics, Inc. | Schematy dawkowania dla 2-hydroksy-6-((2-(1-izopropylo-1H-pirazol-5-ilo)pirydyn3-ylo)metoksy)benzaldehydu |
| TWI663160B (zh) | 2016-05-12 | 2019-06-21 | 全球血液治療公司 | 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法 |
| TW202332423A (zh) | 2016-10-12 | 2023-08-16 | 美商全球血液治療公司 | 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑 |
| EP3860975B1 (en) | 2018-10-01 | 2023-10-18 | Global Blood Therapeutics, Inc. | Modulators of hemoglobin for the treatment of sickle cell disease |
| US12479816B2 (en) | 2019-02-08 | 2025-11-25 | University of Pittsburgh—of the Commonwealth System of Higher Education | 20-HETE formation inhibitors |
| CN112341433A (zh) * | 2020-11-16 | 2021-02-09 | 成都大学 | 一种氯雷他定的制备方法 |
| JP2026524090A (ja) * | 2023-06-08 | 2026-07-17 | 上海森▲輝▼医▲葯▼有限公司 | ホルムアミド系化合物の製造方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| JP2875393B2 (ja) * | 1993-10-15 | 1999-03-31 | シェーリング コーポレイション | Ｇ−タンパク質機能の阻害および増殖性疾患の治療に有用な三環式カルバメート化合物 |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| SK86198A3 (en) * | 1995-12-22 | 1999-02-11 | Schering Corp | Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases |
-
1997
- 1997-06-16 US US08/882,753 patent/US5760232A/en not_active Expired - Lifetime
-
1998
- 1998-06-12 MY MYPI98002633A patent/MY133531A/en unknown
- 1998-06-12 AR ARP980102809A patent/AR015886A1/es unknown
- 1998-06-15 PT PT98928873T patent/PT991640E/pt unknown
- 1998-06-15 EP EP98928873A patent/EP0991640B1/en not_active Expired - Lifetime
- 1998-06-15 JP JP50447999A patent/JP3210023B2/ja not_active Expired - Fee Related
- 1998-06-15 AT AT98928873T patent/ATE214062T1/de not_active IP Right Cessation
- 1998-06-15 DE DE69804100T patent/DE69804100T2/de not_active Expired - Lifetime
- 1998-06-15 CA CA002293709A patent/CA2293709C/en not_active Expired - Fee Related
- 1998-06-15 IN IN1294MA1998 patent/IN187755B/en unknown
- 1998-06-15 WO PCT/US1998/011403 patent/WO1998057958A1/en not_active Ceased
- 1998-06-15 ES ES98928873T patent/ES2169917T3/es not_active Expired - Lifetime
- 1998-06-15 ZA ZA985207A patent/ZA985207B/xx unknown
- 1998-06-15 AU AU80568/98A patent/AU8056898A/en not_active Abandoned
- 1998-06-15 DK DK98928873T patent/DK0991640T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0991640A1 (en) | 2000-04-12 |
| US5760232A (en) | 1998-06-02 |
| ATE214062T1 (de) | 2002-03-15 |
| JP3210023B2 (ja) | 2001-09-17 |
| DE69804100D1 (de) | 2002-04-11 |
| AR015886A1 (es) | 2001-05-30 |
| ZA985207B (en) | 1999-04-07 |
| DE69804100T2 (de) | 2002-10-31 |
| DK0991640T3 (da) | 2002-05-27 |
| IN187755B (enExample) | 2002-06-15 |
| CA2293709A1 (en) | 1998-12-23 |
| MY133531A (en) | 2007-11-30 |
| EP0991640B1 (en) | 2002-03-06 |
| CA2293709C (en) | 2004-02-10 |
| AU8056898A (en) | 1999-01-04 |
| JP2000513032A (ja) | 2000-10-03 |
| ES2169917T3 (es) | 2002-07-16 |
| WO1998057958A1 (en) | 1998-12-23 |
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