AU8056898A - Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds - Google Patents

Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds

Info

Publication number
AU8056898A
AU8056898A AU80568/98A AU8056898A AU8056898A AU 8056898 A AU8056898 A AU 8056898A AU 80568/98 A AU80568/98 A AU 80568/98A AU 8056898 A AU8056898 A AU 8056898A AU 8056898 A AU8056898 A AU 8056898A
Authority
AU
Australia
Prior art keywords
synthesis
intermediates useful
tricyclic compounds
substituted tricyclic
preparing bromo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU80568/98A
Other languages
English (en)
Inventor
Xing Chen
Marc Poirier
Yee-Shing Wong
Guang-Zhong Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp & Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AU8056898A publication Critical patent/AU8056898A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
AU80568/98A 1997-06-16 1998-06-15 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds Abandoned AU8056898A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/882,753 US5760232A (en) 1997-06-16 1997-06-16 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds
US08882753 1997-06-16
PCT/US1998/011403 WO1998057958A1 (en) 1997-06-16 1998-06-15 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds

Publications (1)

Publication Number Publication Date
AU8056898A true AU8056898A (en) 1999-01-04

Family

ID=25381267

Family Applications (1)

Application Number Title Priority Date Filing Date
AU80568/98A Abandoned AU8056898A (en) 1997-06-16 1998-06-15 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds

Country Status (15)

Country Link
US (1) US5760232A (enExample)
EP (1) EP0991640B1 (enExample)
JP (1) JP3210023B2 (enExample)
AR (1) AR015886A1 (enExample)
AT (1) ATE214062T1 (enExample)
AU (1) AU8056898A (enExample)
CA (1) CA2293709C (enExample)
DE (1) DE69804100T2 (enExample)
DK (1) DK0991640T3 (enExample)
ES (1) ES2169917T3 (enExample)
IN (1) IN187755B (enExample)
MY (1) MY133531A (enExample)
PT (1) PT991640E (enExample)
WO (1) WO1998057958A1 (enExample)
ZA (1) ZA985207B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998620A (en) * 1997-03-25 1999-12-07 Schering Corporation Synthesis of intermediates useful in preparing tricyclic compounds
PT1556358E (pt) * 2002-10-03 2007-09-25 Schering Corp ''alquilação enantiosselectiva de compostos tricíclicos''
PL2797416T3 (pl) 2011-12-28 2017-12-29 Global Blood Therapeutics, Inc. Podstawione związki benzaldehydowe i sposoby ich zastosowania do zwiększania natlenienia tkanek
US9012450B2 (en) 2011-12-28 2015-04-21 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
BR112015021982B1 (pt) 2013-03-15 2022-12-13 Global Blood Therapeutics, Inc Compostos e seus usos para a modulação de hemoglobina
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
WO2014145040A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
EP2968299B1 (en) 2013-03-15 2021-01-20 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
JP6426694B2 (ja) 2013-03-15 2018-11-21 グローバル ブラッド セラピューティクス インコーポレイテッド ヘモグロビンの修飾のための化合物及びその使用
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
AP2016009261A0 (en) 2014-02-07 2016-06-30 Global Blood Therapeutics Inc Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
PL3383392T3 (pl) 2015-12-04 2025-11-17 Global Blood Therapeutics, Inc. Schematy dawkowania dla 2-hydroksy-6-((2-(1-izopropylo-1H-pirazol-5-ilo)pirydyn3-ylo)metoksy)benzaldehydu
TWI663160B (zh) 2016-05-12 2019-06-21 全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
EP3860975B1 (en) 2018-10-01 2023-10-18 Global Blood Therapeutics, Inc. Modulators of hemoglobin for the treatment of sickle cell disease
US12479816B2 (en) 2019-02-08 2025-11-25 University of Pittsburgh—of the Commonwealth System of Higher Education 20-HETE formation inhibitors
CN112341433A (zh) * 2020-11-16 2021-02-09 成都大学 一种氯雷他定的制备方法
JP2026524090A (ja) * 2023-06-08 2026-07-17 上海森▲輝▼医▲葯▼有限公司 ホルムアミド系化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
JP2875393B2 (ja) * 1993-10-15 1999-03-31 シェーリング コーポレイション Ｇ−タンパク質機能の阻害および増殖性疾患の治療に有用な三環式カルバメート化合物
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
SK86198A3 (en) * 1995-12-22 1999-02-11 Schering Corp Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases

Also Published As

Publication number Publication date
EP0991640A1 (en) 2000-04-12
US5760232A (en) 1998-06-02
ATE214062T1 (de) 2002-03-15
JP3210023B2 (ja) 2001-09-17
DE69804100D1 (de) 2002-04-11
AR015886A1 (es) 2001-05-30
ZA985207B (en) 1999-04-07
DE69804100T2 (de) 2002-10-31
DK0991640T3 (da) 2002-05-27
PT991640E (pt) 2002-07-31
IN187755B (enExample) 2002-06-15
CA2293709A1 (en) 1998-12-23
MY133531A (en) 2007-11-30
EP0991640B1 (en) 2002-03-06
CA2293709C (en) 2004-02-10
JP2000513032A (ja) 2000-10-03
ES2169917T3 (es) 2002-07-16
WO1998057958A1 (en) 1998-12-23

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase