ATE227733T1 - Herstellung von avermectin-verbindungen - Google Patents
Herstellung von avermectin-verbindungenInfo
- Publication number
- ATE227733T1 ATE227733T1 AT98924534T AT98924534T ATE227733T1 AT E227733 T1 ATE227733 T1 AT E227733T1 AT 98924534 T AT98924534 T AT 98924534T AT 98924534 T AT98924534 T AT 98924534T AT E227733 T1 ATE227733 T1 AT E227733T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- avermectin compounds
- avermectin
- compounds
- Prior art date
Links
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical class C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB9700916 | 1997-07-23 | ||
| PCT/IB1998/000988 WO1999005156A1 (en) | 1997-07-23 | 1998-06-25 | Production of avermectin compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE227733T1 true ATE227733T1 (de) | 2002-11-15 |
Family
ID=11004591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98924534T ATE227733T1 (de) | 1997-07-23 | 1998-06-25 | Herstellung von avermectin-verbindungen |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1001962B8 (de) |
| JP (1) | JP3267634B2 (de) |
| KR (1) | KR100339191B1 (de) |
| CN (1) | CN1184227C (de) |
| AR (1) | AR016522A1 (de) |
| AT (1) | ATE227733T1 (de) |
| AU (1) | AU725506B2 (de) |
| CA (1) | CA2294928C (de) |
| CZ (1) | CZ296326B6 (de) |
| DE (1) | DE69809433T2 (de) |
| DK (1) | DK1001962T3 (de) |
| ES (1) | ES2182317T3 (de) |
| HU (1) | HUP0004631A3 (de) |
| ID (1) | ID24327A (de) |
| IL (1) | IL133558A0 (de) |
| PL (1) | PL188159B1 (de) |
| PT (1) | PT1001962E (de) |
| RU (1) | RU2211221C2 (de) |
| TR (1) | TR200000196T2 (de) |
| WO (1) | WO1999005156A1 (de) |
| YU (1) | YU71699A (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102144163A (zh) | 2008-04-10 | 2011-08-03 | 麻省理工学院 | 关于鉴定和使用靶向癌症干细胞的试剂的方法 |
| US10106778B2 (en) | 2012-11-08 | 2018-10-23 | Whitehead Institute For Biomedical Research | Selective targeting of cancer stem cells |
| US10398672B2 (en) | 2014-04-29 | 2019-09-03 | Whitehead Institute For Biomedical Research | Methods and compositions for targeting cancer stem cells |
| CN104430397B (zh) * | 2014-11-06 | 2016-08-24 | 山东永泰化工有限公司 | 一种用于防治红蜘蛛的水分散粒剂 |
| CN107021990B (zh) * | 2017-06-14 | 2019-07-12 | 博瑞生物医药（苏州）股份有限公司 | 高纯度塞拉菌素的制备方法 |
| CN107118247B (zh) * | 2017-06-14 | 2019-07-26 | 博瑞生物医药（苏州）股份有限公司 | 塞拉菌素的制备方法 |
| CN107188915B (zh) * | 2017-07-19 | 2019-08-02 | 苏州正永生物医药有限公司 | 一种塞拉菌素中间体的制备方法 |
| CN107723325B (zh) * | 2017-11-28 | 2021-03-30 | 山东齐发药业有限公司 | 基于pH控制的多拉菌素发酵生产方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4328335A (en) | 1979-08-13 | 1982-05-04 | Merck & Co., Inc. | Process for the interconversion of C-076 compounds |
| US5015630A (en) * | 1989-01-19 | 1991-05-14 | Merck & Co., Inc. | 5-oxime avermectin derivatives |
| GB9205007D0 (en) * | 1992-03-07 | 1992-04-22 | Pfizer Ltd | Antiparasitic agents |
| GB9402916D0 (en) * | 1994-02-16 | 1994-04-06 | Pfizer Ltd | Antiparasitic agents |
| EP0676236A1 (de) * | 1994-04-05 | 1995-10-11 | Pfizer Inc. | Verfahren zur Entfernung der Allylgruppe oder Allyloxycarbonylgruppe |
-
1998
- 1998-06-25 KR KR1019997012102A patent/KR100339191B1/ko not_active Expired - Fee Related
- 1998-06-25 ES ES98924534T patent/ES2182317T3/es not_active Expired - Lifetime
- 1998-06-25 WO PCT/IB1998/000988 patent/WO1999005156A1/en not_active Ceased
- 1998-06-25 CZ CZ20000097A patent/CZ296326B6/cs not_active IP Right Cessation
- 1998-06-25 CA CA002294928A patent/CA2294928C/en not_active Expired - Fee Related
- 1998-06-25 PL PL98338354A patent/PL188159B1/pl not_active IP Right Cessation
- 1998-06-25 YU YU71699A patent/YU71699A/sh unknown
- 1998-06-25 DE DE69809433T patent/DE69809433T2/de not_active Expired - Fee Related
- 1998-06-25 EP EP98924534A patent/EP1001962B8/de not_active Expired - Lifetime
- 1998-06-25 CN CNB988074524A patent/CN1184227C/zh not_active Expired - Fee Related
- 1998-06-25 AT AT98924534T patent/ATE227733T1/de not_active IP Right Cessation
- 1998-06-25 TR TR2000/00196T patent/TR200000196T2/xx unknown
- 1998-06-25 JP JP50956999A patent/JP3267634B2/ja not_active Expired - Fee Related
- 1998-06-25 HU HU0004631A patent/HUP0004631A3/hu unknown
- 1998-06-25 PT PT98924534T patent/PT1001962E/pt unknown
- 1998-06-25 DK DK98924534T patent/DK1001962T3/da active
- 1998-06-25 ID IDW20000094A patent/ID24327A/id unknown
- 1998-06-25 AU AU76714/98A patent/AU725506B2/en not_active Ceased
- 1998-06-25 IL IL13355898A patent/IL133558A0/xx unknown
- 1998-06-25 RU RU2000101832/04A patent/RU2211221C2/ru not_active IP Right Cessation
- 1998-07-21 AR ARP980103569A patent/AR016522A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0004631A2 (hu) | 2001-05-28 |
| DE69809433D1 (de) | 2002-12-19 |
| DK1001962T3 (da) | 2002-12-16 |
| JP2000513385A (ja) | 2000-10-10 |
| YU71699A (sh) | 2002-06-19 |
| CN1265113A (zh) | 2000-08-30 |
| EP1001962B1 (de) | 2002-11-13 |
| ID24327A (id) | 2000-07-13 |
| JP3267634B2 (ja) | 2002-03-18 |
| TR200000196T2 (tr) | 2000-07-21 |
| AU725506B2 (en) | 2000-10-12 |
| EP1001962B8 (de) | 2003-03-05 |
| WO1999005156A1 (en) | 1999-02-04 |
| CN1184227C (zh) | 2005-01-12 |
| HUP0004631A3 (en) | 2002-11-28 |
| ES2182317T3 (es) | 2003-03-01 |
| AR016522A1 (es) | 2001-07-25 |
| EP1001962A1 (de) | 2000-05-24 |
| RU2211221C2 (ru) | 2003-08-27 |
| PL338354A1 (en) | 2000-10-23 |
| CA2294928C (en) | 2003-01-14 |
| CZ200097A3 (cs) | 2000-05-17 |
| IL133558A0 (en) | 2001-04-30 |
| AU7671498A (en) | 1999-02-16 |
| KR100339191B1 (ko) | 2002-06-01 |
| DE69809433T2 (de) | 2003-05-08 |
| CZ296326B6 (cs) | 2006-02-15 |
| PT1001962E (pt) | 2003-01-31 |
| PL188159B1 (pl) | 2004-12-31 |
| KR20010014066A (ko) | 2001-02-26 |
| CA2294928A1 (en) | 1999-02-04 |
| HK1027110A1 (en) | 2001-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1001962 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |