PT98381A - Metodo para aumentar a resposta imune a antigenios com proteina de classe ii da membrana exterior de neisseria meningitidis - Google Patents

Metodo para aumentar a resposta imune a antigenios com proteina de classe ii da membrana exterior de neisseria meningitidis Download PDF

Info

Publication number
PT98381A
PT98381A PT98381A PT9838191A PT98381A PT 98381 A PT98381 A PT 98381A PT 98381 A PT98381 A PT 98381A PT 9838191 A PT9838191 A PT 9838191A PT 98381 A PT98381 A PT 98381A
Authority
PT
Portugal
Prior art keywords
protein
miep
outer membrane
antigens
prp
Prior art date
Application number
PT98381A
Other languages
English (en)
Portuguese (pt)
Inventor
Allen I Oliff
Margaret A Liu
Arthur Friedman
Joseph Y Tai
John J Donnelly
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT98381A publication Critical patent/PT98381A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
PT98381A 1990-07-19 1991-07-18 Metodo para aumentar a resposta imune a antigenios com proteina de classe ii da membrana exterior de neisseria meningitidis PT98381A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55520490A 1990-07-19 1990-07-19
US63945791A 1991-01-10 1991-01-10

Publications (1)

Publication Number Publication Date
PT98381A true PT98381A (pt) 1992-05-29

Family

ID=27070823

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98381A PT98381A (pt) 1990-07-19 1991-07-18 Metodo para aumentar a resposta imune a antigenios com proteina de classe ii da membrana exterior de neisseria meningitidis

Country Status (9)

Country Link
JP (1) JPH0656690A (ja)
KR (1) KR920002631A (ja)
AU (1) AU8114091A (ja)
CA (1) CA2047043A1 (ja)
FI (1) FI913473A (ja)
IL (1) IL98837A0 (ja)
MX (1) MX9100272A (ja)
NO (1) NO912822L (ja)
PT (1) PT98381A (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003527079A (ja) * 1999-04-30 2003-09-16 カイロン コーポレイション ナイセリアゲノム配列およびそれらの使用方法
GB0011108D0 (en) * 2000-05-08 2000-06-28 Microscience Ltd Virulence gene and protein and their use

Also Published As

Publication number Publication date
MX9100272A (es) 1992-02-28
CA2047043A1 (en) 1992-01-20
KR920002631A (ko) 1992-02-28
NO912822D0 (no) 1991-07-18
NO912822L (no) 1992-01-20
FI913473A (fi) 1992-01-20
IL98837A0 (en) 1992-07-15
JPH0656690A (ja) 1994-03-01
AU8114091A (en) 1992-01-23
FI913473A0 (fi) 1991-07-18

Similar Documents

Publication Publication Date Title
EP0467714A1 (en) The class II protein of the outer membrane of neisseria meningitidis
EP0186576B1 (en) Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates
US4695624A (en) Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
FI111336B (fi) Menetelmä Staphylococcus epidermidis tyyppi I:n polysakkaridiantigeenin sisältävän rokotteen ja antigeeninvastaisen hyperimmunoglobuliinin valmistamiseksi
US4882317A (en) Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers and methods of preparing such polysaccharides and conjugataes and of confirming covalency
ES2621359T3 (es) Polisacáridos modificados para vacunas conjugadas
EA006947B1 (ru) Поливалентная менингококковая полисахаридно-белковая конъюгированная вакцина
JPH0662434B2 (ja) グラム陰性菌による感染に対する接合ワクチン及びその使用法
CN110214022A (zh) 免疫原性缀合物及其用途
JP5490341B2 (ja) Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ感染のための多糖ワクチン
ES2847947T3 (es) Conjugados de VMEn-antígeno nativas y uso de los mismos
CN102458478A (zh) 白蛋白-淀粉样肽缀合物及其用途
PT98381A (pt) Metodo para aumentar a resposta imune a antigenios com proteina de classe ii da membrana exterior de neisseria meningitidis
EP0519554A1 (en) Conjugates of the class II protein of the outer membrane of neisseria meningitidis and of HIV-1 related peptides
IL165970A (en) Method of isolating biologically active fraction containing clinically acceptable native s-lipopolysaccharides obtained from bacteria producing endotoxic lipopolysaccharides
US7408075B1 (en) Synthesis of phosphocholine ester derivatives and conjugates thereof
JPH0616569A (ja) 免疫学的担体特性および免疫促進特性を有するナイセリア・メニンギチジスの外膜のクラスｉｉ蛋白、およびそれを含むワクチン
AU2001269640B2 (en) Vaccine against the influenza virus and method for producing said virus vaccine
RU2407792C1 (ru) СПОСОБ ПОЛУЧЕНИЯ IgAl-ПРОТЕАЗЫ ИЗ КУЛЬТУРЫ NEISSERIA MENINGITIDIS СЕРОГРУППЫ А И ИММУНОГЕННЫЙ ПРЕПАРАТ НА ЕЕ ОСНОВЕ
JPS60161926A (ja) オリゴームラミルペプチド含有組成物
CN113663066B (zh) 一种肌醇阿拉伯甘露寡糖缀合物及在抗结核疫苗中的应用
CN108367062A (zh) 抗金黄色葡萄球菌的免疫原性组合物
EA025417B1 (ru) Вакцины с повышенной иммуногенностью и способы их получения
JPH02215797A (ja) ポリペプチド
PT98383A (pt) Processo para a preparacao de uma proteina de classe ii da membrana exterior de neisseria meningitidis tendo propriedades de veiculo e de intensificacao imunologicas

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920122

FC3A Refusal

Effective date: 19981007