PT97396A - Processo para a preparacao de derivados de amina e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de derivados de amina e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT97396A PT97396A PT97396A PT9739691A PT97396A PT 97396 A PT97396 A PT 97396A PT 97396 A PT97396 A PT 97396A PT 9739691 A PT9739691 A PT 9739691A PT 97396 A PT97396 A PT 97396A
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- alkenyl
- hydrogen
- phenyl
- phenylalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Liquid Crystal Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909008818A GB9008818D0 (en) | 1990-04-19 | 1990-04-19 | Amine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
PT97396A true PT97396A (pt) | 1992-01-31 |
PT97396B PT97396B (pt) | 1998-08-31 |
Family
ID=10674667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT97396A PT97396B (pt) | 1990-04-19 | 1991-04-18 | Processo para a preparacao de derivados de amina e de composicoes farmaceuticas que os contem |
Country Status (17)
Country | Link |
---|---|
US (1) | US5654298A (pt) |
EP (1) | EP0453197B1 (pt) |
JP (1) | JP3068875B2 (pt) |
AT (1) | ATE107286T1 (pt) |
AU (1) | AU642482B2 (pt) |
CA (1) | CA2040107A1 (pt) |
DE (1) | DE69102481T2 (pt) |
DK (1) | DK0453197T3 (pt) |
ES (1) | ES2055535T3 (pt) |
FI (1) | FI911925A (pt) |
GB (1) | GB9008818D0 (pt) |
IE (1) | IE64361B1 (pt) |
IL (1) | IL97751A0 (pt) |
NO (1) | NO911347L (pt) |
NZ (1) | NZ237689A (pt) |
PT (1) | PT97396B (pt) |
ZA (1) | ZA912672B (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5445946A (en) * | 1993-04-13 | 1995-08-29 | Molecular Probes, Inc. | Intravacuolar stains for yeast and other fungi |
US5534416A (en) * | 1993-04-13 | 1996-07-09 | Molecular Probes, Inc. | Fluorescent viability assay using cyclic-substituted unsymmetrical cyanine dyes |
US5545535A (en) * | 1993-04-13 | 1996-08-13 | Molecular Probes, Inc. | Fluorescent assay for bacterial gram reaction |
US5436134A (en) * | 1993-04-13 | 1995-07-25 | Molecular Probes, Inc. | Cyclic-substituted unsymmetrical cyanine dyes |
FR2737496B1 (fr) * | 1995-07-31 | 1997-12-19 | Centre Nat Rech Scient | 4-aryl-thio-pyridin-2(1h)-ones, medicaments les contenant et leurs utilisations dans le traitement de maladies liees aux vih 1 et 2 |
US8309562B2 (en) * | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
NZ544472A (en) * | 2003-07-03 | 2009-04-30 | Myriad Genetics Inc | Compounds and therapeutical use thereof |
US7776529B2 (en) | 2003-12-05 | 2010-08-17 | Life Technologies Corporation | Methine-substituted cyanine dye compounds |
AU2005286593A1 (en) * | 2004-09-23 | 2006-03-30 | Reddy Us Therapeutics, Inc. | Novel pyridine compounds, process for their preparation and compositions containing them |
CA2592900A1 (en) | 2005-01-03 | 2006-07-13 | Myriad Genetics Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
US8258145B2 (en) * | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
US7598390B2 (en) | 2005-05-11 | 2009-10-06 | Life Technologies Corporation | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use |
US20100183513A1 (en) * | 2006-11-24 | 2010-07-22 | Wolfgang Froestl | N-(methyl) -1h-pyrazol-3-amine, n-(methyl)-pyridin-2-amine and n-(methyl)-thiazol-2-amine derivatives for the treatment of diseases associated with amyloid or amyloid-like proteins, like e.g. alzheimer's |
WO2023151560A1 (en) * | 2022-02-08 | 2023-08-17 | Etern Biopharma (Shanghai) Co., Ltd. | Bicyclic heteroaryl compounds and uses thereof |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB815833A (en) * | 1956-09-26 | 1959-07-01 | Boots Pure Drug Co Ltd | Phenanthridine compounds |
BE492034A (pt) * | 1948-11-05 | |||
US2748124A (en) * | 1954-05-06 | 1956-05-29 | Searle & Co | 1-(4-anilino-2-pyrimidino)-3-alkylureas |
GB814947A (en) * | 1954-08-16 | 1959-06-17 | Geigy Ag J R | Improvements in and relating to plant growth influencing compositions |
US2845425A (en) * | 1956-10-04 | 1958-07-29 | Lilly Co Eli | Substituted aminopyrimidines |
DE1241832B (de) * | 1963-02-23 | 1967-06-08 | Hoechst Ag | Verfahren zur Herstellung von Pyrimidiniumverbindungen |
DE1445740A1 (de) * | 1963-09-04 | 1968-11-28 | Bayer Ag | Verfahren zur Herstellung von Bispyrimidinium-Verbindungen |
NL131196C (pt) * | 1966-07-16 | |||
GB1229413A (pt) * | 1967-06-14 | 1971-04-21 | ||
BE786565A (fr) * | 1971-07-23 | 1973-01-22 | Upjohn Co | Nouveaux oxydes de pyridine substitues et leur preparation |
ZA743270B (en) * | 1973-06-15 | 1975-05-28 | Upjohn Co | Anti-hypertensive compounds |
IN142539B (pt) * | 1974-05-10 | 1977-07-23 | Ciba Geigy India Ltd | |
US4339453A (en) * | 1979-07-23 | 1982-07-13 | Merck & Co., Inc. | Antimicrobial aminopyrimidinium salts |
US4287338A (en) * | 1980-03-10 | 1981-09-01 | The Upjohn Company | Sulfooxy-pyrimidinium, -pyridinium, and -triazinium hydroxide inner salts |
FR2524467A1 (fr) * | 1982-03-30 | 1983-10-07 | Adir | Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant |
FR2544315B1 (fr) * | 1983-04-12 | 1985-07-05 | Adir | Polymethylene imines disubstituees, leurs procedes de preparation, et les compositions pharmaceutiques les renfermant |
US4503050A (en) * | 1983-06-02 | 1985-03-05 | Riker Laboratories, Inc. | Substituted imidazo[1,2-c]pyrimidines |
EP0139613A1 (de) * | 1983-08-29 | 1985-05-02 | Ciba-Geigy Ag | N-(2-Nitrophenyl)-4-aminopyrimidin-Derivate, deren Herstellung und Verwendung |
US4725600A (en) * | 1984-07-13 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent |
JPS61218589A (ja) * | 1985-03-26 | 1986-09-29 | Eisai Co Ltd | 5―(6―イミダゾ〔1,2―a〕ピリジニル)ピリジン誘導体 |
DE3514073A1 (de) * | 1985-04-18 | 1986-10-23 | Hoechst Ag, 6230 Frankfurt | Mehrfach substituierte pyridin-1-oxide, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung |
WO1987001706A2 (en) * | 1985-09-12 | 1987-03-26 | The Upjohn Company | C20 through c26 amino steroids |
DE3703633A1 (de) * | 1986-02-14 | 1987-08-20 | Sandoz Ag | Purin-derivate, ihre herstellung und sie enthaltende arzneimittel |
US4729995A (en) * | 1986-04-21 | 1988-03-08 | Toyo Boseki Kabushiki Kaisha | Pyrimidine 2,4-dioxamate compounds and pharmaceutical compositions |
US5019565A (en) * | 1986-05-02 | 1991-05-28 | Ici Americas Inc. | Fungicidal pyridyl imidates |
DE3639563A1 (de) * | 1986-11-20 | 1988-06-01 | Basf Ag | N-arylsulfonyl-n'-pyrimidyl(triazinyl) -harnstoffe |
DE3717480A1 (de) * | 1987-05-23 | 1988-12-01 | Shell Agrar Gmbh & Co Kg | Neue herbizid und mikrobizid wirksame 2,6-diaminopyrimidine |
IL88507A (en) * | 1987-12-03 | 1993-02-21 | Smithkline Beckman Intercredit | 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them |
GB8808071D0 (en) * | 1988-04-07 | 1988-05-11 | Shell Int Research | Triazine herbicides |
GB8819494D0 (en) * | 1988-08-16 | 1988-09-21 | Ucb Sa | Use of 2-amino-4-morpholino-6-propyl-1 3 5-triazines for preparation of psychotropic medicaments |
GB8819493D0 (en) * | 1988-08-16 | 1988-09-21 | Ucb Sa | 2-amino-4-morpholino-6-propyl-1 3 5-triazines |
US4992448A (en) * | 1989-10-24 | 1991-02-12 | Hoechst-Roussel Pharmaceuticals Inc. | Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders |
-
1990
- 1990-04-19 GB GB909008818A patent/GB9008818D0/en active Pending
-
1991
- 1991-03-27 IE IE102491A patent/IE64361B1/en not_active IP Right Cessation
- 1991-04-02 IL IL97751A patent/IL97751A0/xx unknown
- 1991-04-02 AU AU73943/91A patent/AU642482B2/en not_active Ceased
- 1991-04-04 NZ NZ237689A patent/NZ237689A/en unknown
- 1991-04-05 NO NO91911347A patent/NO911347L/no unknown
- 1991-04-09 CA CA002040107A patent/CA2040107A1/en not_active Abandoned
- 1991-04-10 ZA ZA912672A patent/ZA912672B/xx unknown
- 1991-04-12 ES ES91303275T patent/ES2055535T3/es not_active Expired - Lifetime
- 1991-04-12 EP EP91303275A patent/EP0453197B1/en not_active Expired - Lifetime
- 1991-04-12 DK DK91303275.1T patent/DK0453197T3/da active
- 1991-04-12 AT AT91303275T patent/ATE107286T1/de not_active IP Right Cessation
- 1991-04-12 DE DE69102481T patent/DE69102481T2/de not_active Expired - Fee Related
- 1991-04-15 JP JP3082095A patent/JP3068875B2/ja not_active Expired - Lifetime
- 1991-04-16 US US07/685,944 patent/US5654298A/en not_active Expired - Fee Related
- 1991-04-18 PT PT97396A patent/PT97396B/pt not_active IP Right Cessation
- 1991-04-19 FI FI911925A patent/FI911925A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ES2055535T3 (es) | 1994-08-16 |
NO911347D0 (no) | 1991-04-05 |
GB9008818D0 (en) | 1990-06-13 |
NZ237689A (en) | 1993-11-25 |
JPH04224562A (ja) | 1992-08-13 |
ATE107286T1 (de) | 1994-07-15 |
AU7394391A (en) | 1991-10-24 |
NO911347L (no) | 1991-10-21 |
IL97751A0 (en) | 1992-06-21 |
FI911925A0 (fi) | 1991-04-19 |
EP0453197B1 (en) | 1994-06-15 |
US5654298A (en) | 1997-08-05 |
CA2040107A1 (en) | 1991-10-20 |
JP3068875B2 (ja) | 2000-07-24 |
IE911024A1 (en) | 1991-10-23 |
AU642482B2 (en) | 1993-10-21 |
EP0453197A1 (en) | 1991-10-23 |
DK0453197T3 (da) | 1994-10-24 |
FI911925A (fi) | 1991-10-20 |
DE69102481D1 (de) | 1994-07-21 |
ZA912672B (en) | 1991-12-24 |
PT97396B (pt) | 1998-08-31 |
DE69102481T2 (de) | 1994-09-29 |
IE64361B1 (en) | 1995-07-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19910912 |
|
FG3A | Patent granted, date of granting |
Effective date: 19980511 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20011130 |