PT956287E - Derivados de 3-aril-2-(1-substituido-4-piperidinil)-1(1-di)oxo-3h-benzo¬disotiazol sua preparacao e sua utilizacao como moduladores da funcao neurotransmissora - Google Patents

Derivados de 3-aril-2-(1-substituido-4-piperidinil)-1(1-di)oxo-3h-benzo¬disotiazol sua preparacao e sua utilizacao como moduladores da funcao neurotransmissora

Info

Publication number
PT956287E
PT956287E PT97950636T PT97950636T PT956287E PT 956287 E PT956287 E PT 956287E PT 97950636 T PT97950636 T PT 97950636T PT 97950636 T PT97950636 T PT 97950636T PT 956287 E PT956287 E PT 956287E
Authority
PT
Portugal
Prior art keywords
neurotransmissant
diisotiazol
piperidinyl
benzo
modulators
Prior art date
Application number
PT97950636T
Other languages
English (en)
Inventor
Gregory H Merriman
Barbara S Rauckman
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of PT956287E publication Critical patent/PT956287E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT97950636T 1996-12-23 1997-11-13 Derivados de 3-aril-2-(1-substituido-4-piperidinil)-1(1-di)oxo-3h-benzo¬disotiazol sua preparacao e sua utilizacao como moduladores da funcao neurotransmissora PT956287E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77486696A 1996-12-23 1996-12-23

Publications (1)

Publication Number Publication Date
PT956287E true PT956287E (pt) 2003-11-28

Family

ID=25102528

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97950636T PT956287E (pt) 1996-12-23 1997-11-13 Derivados de 3-aril-2-(1-substituido-4-piperidinil)-1(1-di)oxo-3h-benzo¬disotiazol sua preparacao e sua utilizacao como moduladores da funcao neurotransmissora

Country Status (17)

Country Link
EP (1) EP0956287B1 (pt)
JP (1) JP3282827B2 (pt)
KR (1) KR20000062283A (pt)
AR (1) AR009440A1 (pt)
AT (1) ATE247111T1 (pt)
AU (1) AU716689B2 (pt)
BR (1) BR9714432A (pt)
CA (1) CA2273181C (pt)
DE (1) DE69724148T2 (pt)
DK (1) DK0956287T3 (pt)
ES (1) ES2200205T3 (pt)
HU (1) HUP9904071A3 (pt)
IL (1) IL130605A0 (pt)
NO (1) NO993085L (pt)
PT (1) PT956287E (pt)
WO (1) WO1998028295A1 (pt)
ZA (1) ZA9711337B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1393351B1 (it) * 2009-03-16 2012-04-20 Eos Ethical Oncology Science Spa In Forma Abbreviata Eos Spa Procedimento per la preparazione della 6-(7-((1-amminociclopropil)metossi)-6-metossichinolin-4-ilossi)-n-metil-1-naftammide e suoi intermedi di sintesi

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2509797C2 (de) * 1975-03-06 1985-07-18 Dr. Karl Thomae Gmbh, 7950 Biberach Phthalimidine, deren physiologisch verträgliche Säureadditionssalze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
AT345806B (de) * 1975-03-06 1978-10-10 Thomae Gmbh Dr K Verfahren zur herstellung neuer substituierter arylalkylamine und deren salze
EP0429341A3 (en) * 1989-11-20 1991-11-13 Rhone-Poulenc Sante Heterocyclic derivatives, their preparation and pharmaceuticals containing them
FR2662696A2 (fr) * 1989-12-13 1991-12-06 Rhone Poulenc Sante Antagonistes de la serotonine, leur preparation et medicaments les contenant.
US5567718A (en) * 1994-08-11 1996-10-22 Hoechst Marion Roussel Inc. 2,3-dihydro-1h-isoindole derivatives and their use as serotonin reuptake inhibitors

Also Published As

Publication number Publication date
AU5358898A (en) 1998-07-17
KR20000062283A (ko) 2000-10-25
JP2001520641A (ja) 2001-10-30
AR009440A1 (es) 2000-04-12
AU716689B2 (en) 2000-03-02
HUP9904071A2 (hu) 2000-05-28
JP3282827B2 (ja) 2002-05-20
DK0956287T3 (da) 2003-11-24
NO993085D0 (no) 1999-06-22
IL130605A0 (en) 2000-06-01
EP0956287B1 (en) 2003-08-13
HUP9904071A3 (en) 2000-07-28
BR9714432A (pt) 2000-05-02
WO1998028295A1 (en) 1998-07-02
EP0956287A1 (en) 1999-11-17
NO993085L (no) 1999-08-20
CA2273181C (en) 2004-01-20
ES2200205T3 (es) 2004-03-01
CA2273181A1 (en) 1998-07-02
ZA9711337B (en) 1998-06-23
DE69724148T2 (de) 2004-06-09
ATE247111T1 (de) 2003-08-15
DE69724148D1 (de) 2003-09-18

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