PT95584A - Processo de preparacao de antraquinonas, dos seus intermediarios e de composicoes farmaceuticas - Google Patents

Processo de preparacao de antraquinonas, dos seus intermediarios e de composicoes farmaceuticas

Info

Publication number
PT95584A
PT95584A PT95584A PT9558490A PT95584A PT 95584 A PT95584 A PT 95584A PT 95584 A PT95584 A PT 95584A PT 9558490 A PT9558490 A PT 9558490A PT 95584 A PT95584 A PT 95584A
Authority
PT
Portugal
Prior art keywords
group
pct
hydroxy
antraquinones
intermediaries
Prior art date
Application number
PT95584A
Other languages
English (en)
Other versions
PT95584B (pt
Inventor
Laurence Hylton Patterson
Original Assignee
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Dev filed Critical Nat Res Dev
Publication of PT95584A publication Critical patent/PT95584A/pt
Publication of PT95584B publication Critical patent/PT95584B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
    • C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
    • C07C291/04—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds containing amino-oxide bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B1/00—Dyes with anthracene nucleus not condensed with any other ring
    • C09B1/50—Amino-hydroxy-anthraquinones; Ethers and esters thereof
    • C09B1/51—N-substituted amino-hydroxy anthraquinone
    • C09B1/515—N-alkyl, N-aralkyl or N-cycloalkyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT95584A 1989-10-13 1990-10-12 Processo de preparacao de antraquinonas, dos seus intermediarios e de composicoes farmaceuticas PT95584B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898923075A GB8923075D0 (en) 1989-10-13 1989-10-13 Anti-cancer compounds

Publications (2)

Publication Number Publication Date
PT95584A true PT95584A (pt) 1991-09-13
PT95584B PT95584B (pt) 1997-08-29

Family

ID=10664506

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95584A PT95584B (pt) 1989-10-13 1990-10-12 Processo de preparacao de antraquinonas, dos seus intermediarios e de composicoes farmaceuticas

Country Status (14)

Country Link
US (1) US5132327A (pt)
EP (1) EP0450021B1 (pt)
JP (1) JP2854971B2 (pt)
AT (1) ATE101181T1 (pt)
AU (1) AU634125B2 (pt)
CA (1) CA2038934C (pt)
DE (1) DE69006482T2 (pt)
DK (1) DK0450021T3 (pt)
ES (1) ES2062558T3 (pt)
GB (2) GB8923075D0 (pt)
NZ (1) NZ235658A (pt)
PT (1) PT95584B (pt)
WO (1) WO1991005824A1 (pt)
ZA (1) ZA908178B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5141957A (en) * 1990-11-02 1992-08-25 Sphinx Pharmaceuticals Corporation 1,4-bis-(amino-hydroxyalkylamino)-anthraquinones for inhibiting protein kinase c
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
GB9107843D0 (en) * 1991-04-12 1991-05-29 Patterson Laurence H Anti-cancer compounds
GB9107852D0 (en) * 1991-04-12 1991-05-29 Patterson Laurence H Anti-cancer compounds
GB9813062D0 (en) * 1998-06-18 1998-08-19 Univ Wales Medicine An anthraquinone and its derivatives
GB9815910D0 (en) 1998-07-21 1998-09-23 Btg Int Ltd Synthetic method
FR2786484B1 (fr) 1998-11-30 2001-01-05 Oreal Aminoanthraquinones cationiques, leur utilisation pour la teinture des fibres keratiniques, compositions tinctoriales les renfermant et procedes de teinture
GB9828670D0 (en) * 1998-12-24 1999-02-17 Univ Montfort Anthraquinone anticancer drugs
GB0112868D0 (en) * 2001-05-25 2001-07-18 Secr Defence Detection system
EP1485349A1 (en) * 2002-03-15 2004-12-15 Btg International Limited Formulations of anthraquinone derivatives
GB0223563D0 (en) * 2002-10-10 2002-11-20 Secr Defence Detection system
US6949557B2 (en) * 2003-04-29 2005-09-27 Dabur Research Foundation Hydroanthracene based compounds as anticancer agents
US20050009924A1 (en) * 2003-07-08 2005-01-13 Hsu-Shan Huang Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives
EP1663147A1 (en) * 2003-09-17 2006-06-07 Btg International Limited Formulations of anthraquinone derivatives
US7557215B2 (en) * 2003-12-23 2009-07-07 Somanta Limited Anthraquinone compounds as anti cancer compounds
JP2007522194A (ja) * 2004-02-13 2007-08-09 クドス ファーマシューティカルズ リミテッド Ａｑ４ｎの製造方法
WO2005097128A1 (en) * 2004-03-30 2005-10-20 Novacea, Inc. 1,4-bis-n-oxide azaanthracenediones and the use thereof
JP2008531720A (ja) * 2005-03-04 2008-08-14 ノバセア インコーポレイティッド 過剰増殖疾患のアントラキノンによる治療
US20070117784A1 (en) * 2005-03-04 2007-05-24 Novacea, Inc. Treatment of hyperproliferative diseases with anthraquinones
WO2008103320A1 (en) * 2007-02-16 2008-08-28 Novacea, Inc. Methods of treating ophthalmic disorders with anthraquinones
US8999965B2 (en) 2008-10-27 2015-04-07 Life Technologies Corporation Anthraquinone based near IR emitting compounds and uses thereof
GB201005939D0 (en) 2010-04-09 2010-05-26 Biostatus Ltd Method of analysing a cell or other biological material containing nucleic acid
GB201214169D0 (en) 2012-08-08 2012-09-19 Biostatus Ltd New compounds and uses thereof
WO2014062856A1 (en) 2012-10-16 2014-04-24 Halozyme, Inc. Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods
US9272981B1 (en) * 2015-06-23 2016-03-01 Amazon Technologies, Inc. Method of preparing a compound
US11292803B2 (en) 2018-08-21 2022-04-05 The Board Of Trustees Of The University Of Illinois Bioreducible N-oxide-based probes for imaging of hypoxia

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE194218C (pt) *
US3174994A (en) * 1962-01-30 1965-03-23 Smith Kline French Lab Hypocholesterolemic n-oxide compositions
ZA774443B (en) * 1977-07-22 1978-06-28 Allied Chem Anthrquinone compounds as anti-cancer agents
US4278689A (en) * 1978-07-11 1981-07-14 American Cyanamid Company 1,4-Bis(substituted-amino)-5,8-dihydroxy-anthraquinones and leuco bases thereof
US4138415A (en) * 1978-05-05 1979-02-06 American Cyanamid Company 1,4-Bis(aminoalkylamino)-anthraquinones and leuco derivatives thereof
US4430501A (en) * 1979-08-02 1984-02-07 American Cyanamid Company 1,4-Bis(substituted-amino)-5,8-dihydroxy-anthraquinones and leuco bases thereof
US4197249A (en) * 1977-08-15 1980-04-08 American Cyanamid Company 1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
US4820738A (en) * 1977-08-15 1989-04-11 American Cyanamid Company 1,4-bis(substituted-amino)-5,8-dihydroxy-anthraquinones and leuco bases thereof
US4540519A (en) * 1977-08-15 1985-09-10 American Cyanamid Company 1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
US4526989A (en) * 1978-07-11 1985-07-02 American Cyanamid Company 1,4-Bis (substituted-amino)-5,8-dihydroxy-anthraquinones and leuco bases thereof
US4614618A (en) * 1979-08-02 1986-09-30 American Cyanamid Company 1,4-bis(substituted-amino)-5,8-dihydroxy anthraquinones and leuco bases thereof
US4275010A (en) * 1979-10-24 1981-06-23 American Cyanamid Company 5,8-Dihydroxy-1,4-bis(guanidinylamino)anthraquinones
US4278605A (en) * 1980-06-30 1981-07-14 American Cyanamid Company Heteroalkylenebisanthraquinones
US4555572A (en) * 1983-07-19 1985-11-26 Warner-Lambert Company Pyrazolo[3,4,5-kl]acridine compositions and methods for their production and use
US4626540A (en) * 1983-11-08 1986-12-02 Warner-Lambert Company Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them
US4686218A (en) * 1985-01-30 1987-08-11 Smithkline Beckman Corporation Use of 6-chloro-3-methyl-1H-2,3,4,5-tetrahydro-3-benzazepine-n-oxide, as a prodrug
US4963554A (en) * 1990-02-14 1990-10-16 Ortho Pharmaceutical Corporation 6,7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides

Also Published As

Publication number Publication date
JP2854971B2 (ja) 1999-02-10
GB8923075D0 (en) 1989-11-29
US5132327A (en) 1992-07-21
GB9022217D0 (en) 1990-11-28
AU6539590A (en) 1991-05-16
DE69006482T2 (de) 1994-05-11
ES2062558T3 (es) 1994-12-16
PT95584B (pt) 1997-08-29
ZA908178B (en) 1992-06-24
AU634125B2 (en) 1993-02-11
EP0450021A1 (en) 1991-10-09
ATE101181T1 (de) 1994-02-15
DE69006482D1 (de) 1994-03-17
GB2237283A (en) 1991-05-01
DK0450021T3 (da) 1994-03-07
EP0450021B1 (en) 1994-02-02
NZ235658A (en) 1992-12-23
WO1991005824A1 (en) 1991-05-02
GB2237283B (en) 1993-01-27
JPH04502166A (ja) 1992-04-16
CA2038934A1 (en) 1991-04-14
CA2038934C (en) 2002-11-19

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Legal Events

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BB1A Laying open of patent application

Effective date: 19910321

NF3A Restitutio in integrum

Free format text: RESTITUTIO IN INTEGRUM

Effective date: 20031202

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20091123