PT951311E - Dispositivo para aplicar numa mistura de dois ou mais componentes líquidos para formar um biomaterial - Google Patents
Dispositivo para aplicar numa mistura de dois ou mais componentes líquidos para formar um biomaterial Download PDFInfo
- Publication number
- PT951311E PT951311E PT97946656T PT97946656T PT951311E PT 951311 E PT951311 E PT 951311E PT 97946656 T PT97946656 T PT 97946656T PT 97946656 T PT97946656 T PT 97946656T PT 951311 E PT951311 E PT 951311E
- Authority
- PT
- Portugal
- Prior art keywords
- liquid
- liquids
- nozzle
- diameter
- spray
- Prior art date
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 119
- 239000012620 biological material Substances 0.000 title claims abstract description 13
- 239000000203 mixture Substances 0.000 title claims description 17
- 239000007921 spray Substances 0.000 claims abstract description 85
- 238000002156 mixing Methods 0.000 claims abstract description 26
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 claims abstract description 18
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical group CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims description 23
- 108010073651 fibrinmonomer Proteins 0.000 claims description 14
- 108010049003 Fibrinogen Proteins 0.000 claims description 10
- 102000008946 Fibrinogen Human genes 0.000 claims description 10
- 229940012952 fibrinogen Drugs 0.000 claims description 10
- 239000012530 fluid Substances 0.000 claims description 7
- 238000004891 communication Methods 0.000 claims description 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 238000003776 cleavage reaction Methods 0.000 claims 1
- 230000000379 polymerizing effect Effects 0.000 claims 1
- 230000007017 scission Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 31
- 239000003894 surgical glue Substances 0.000 abstract description 8
- 239000000443 aerosol Substances 0.000 abstract description 6
- -1 e.g. Substances 0.000 abstract 1
- 239000007789 gas Substances 0.000 description 52
- 239000000306 component Substances 0.000 description 50
- 239000000565 sealant Substances 0.000 description 38
- 239000000243 solution Substances 0.000 description 17
- 108010073385 Fibrin Proteins 0.000 description 9
- 102000009123 Fibrin Human genes 0.000 description 9
- 229950003499 fibrin Drugs 0.000 description 9
- 239000000463 material Substances 0.000 description 9
- 238000005507 spraying Methods 0.000 description 7
- 230000007704 transition Effects 0.000 description 7
- 108090000190 Thrombin Proteins 0.000 description 6
- 229960004072 thrombin Drugs 0.000 description 6
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 230000002028 premature Effects 0.000 description 4
- 229920001169 thermoplastic Polymers 0.000 description 4
- 229920001222 biopolymer Polymers 0.000 description 3
- 239000000872 buffer Substances 0.000 description 3
- 239000007853 buffer solution Substances 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000006116 polymerization reaction Methods 0.000 description 3
- 239000012815 thermoplastic material Substances 0.000 description 3
- 239000004416 thermosoftening plastic Substances 0.000 description 3
- 239000011545 carbonate/bicarbonate buffer Substances 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000011260 co-administration Methods 0.000 description 2
- 230000015271 coagulation Effects 0.000 description 2
- 238000005345 coagulation Methods 0.000 description 2
- 239000013536 elastomeric material Substances 0.000 description 2
- 238000009760 electrical discharge machining Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 229920001684 low density polyethylene Polymers 0.000 description 2
- 239000004702 low-density polyethylene Substances 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 239000000654 additive Substances 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000005553 drilling Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 239000000416 hydrocolloid Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 239000008177 pharmaceutical agent Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical compound [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000003106 tissue adhesive Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
- B05B7/02—Spray pistols; Apparatus for discharge
- B05B7/08—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
- B05B7/02—Spray pistols; Apparatus for discharge
- B05B7/08—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point
- B05B7/0876—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point to form parallel jets constituted by a liquid or a mixture containing a liquid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
- A61B2017/00495—Surgical glue applicators for two-component glue
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Surgical Instruments (AREA)
- Materials For Medical Uses (AREA)
- Nozzles (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3094296P | 1996-11-15 | 1996-11-15 | |
| US08/970,291 US6454786B1 (en) | 1996-11-15 | 1997-11-14 | Devices and methods for applying a mixture of two or more liquid components to form a biomaterial |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT951311E true PT951311E (pt) | 2007-06-05 |
Family
ID=26706614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97946656T PT951311E (pt) | 1996-11-15 | 1997-11-14 | Dispositivo para aplicar numa mistura de dois ou mais componentes líquidos para formar um biomaterial |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6454786B1 (enExample) |
| EP (1) | EP0951311B1 (enExample) |
| JP (2) | JP4116083B2 (enExample) |
| AT (1) | ATE357946T1 (enExample) |
| AU (1) | AU721371B2 (enExample) |
| BR (1) | BR9713070A (enExample) |
| CA (2) | CA2271738C (enExample) |
| DE (1) | DE69737531T2 (enExample) |
| DK (1) | DK0951311T3 (enExample) |
| ES (1) | ES2284186T3 (enExample) |
| IL (1) | IL129916A0 (enExample) |
| NO (1) | NO992342L (enExample) |
| NZ (1) | NZ335751A (enExample) |
| PT (1) | PT951311E (enExample) |
| WO (1) | WO1998020931A1 (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000062828A1 (en) * | 1996-04-30 | 2000-10-26 | Medtronic, Inc. | Autologous fibrin sealant and method for making the same |
| DE29723807U1 (de) * | 1996-04-30 | 1999-11-04 | Medtronic, Inc., Minneapolis, Minn. | Autologe Fibrin-Blutstillungsmittel |
| WO2000015117A1 (en) * | 1998-09-17 | 2000-03-23 | Focal, Inc. | Self-cleaning fluid delivery device for medical applications |
| US6921380B1 (en) * | 1998-10-01 | 2005-07-26 | Baxter International Inc. | Component mixing catheter |
| DE69930155T2 (de) * | 1998-12-02 | 2006-11-23 | Bristol-Myers Squibb Co. | Spray verabreichung von zellen |
| AU764757B2 (en) * | 1999-06-01 | 2003-08-28 | Vivolution A/S | Fibrin polymer structure |
| CA2316554C (en) | 1999-08-25 | 2007-10-23 | Bristol-Myers Squibb Company | Applicator and electro-mechanical applicator drive system |
| US7544177B2 (en) | 2002-01-24 | 2009-06-09 | The Regents Of The University Of California | Aerosol device to deliver bioactive agent |
| US7217254B2 (en) | 2002-09-20 | 2007-05-15 | Genzyme Corporation | Multi-pressure biocompatible agent delivery device and method |
| US7077339B2 (en) * | 2003-02-03 | 2006-07-18 | Biomet, Inc. | Spray applicator |
| US20040254528A1 (en) * | 2003-06-12 | 2004-12-16 | Adams Daniel O. | Catheter with removable wire lumen segment |
| US7490738B2 (en) * | 2004-10-01 | 2009-02-17 | Angiotech Pharmaceuticals (Us), Inc. | Mixing and dispensing fluid components of a multicomponent composition |
| PL1871237T3 (pl) * | 2005-01-12 | 2013-05-31 | Baxter Int | Ręcznie wyzwalany aparat rozpraszający klej tkankowy oraz układ |
| US7611494B2 (en) * | 2005-02-08 | 2009-11-03 | Confluent Surgical, Inc. | Spray for fluent materials |
| EP2433590B1 (en) * | 2005-02-18 | 2020-05-06 | Covidien LP | Rapid exchange catheter with embolic filter |
| US7766900B2 (en) * | 2005-02-21 | 2010-08-03 | Biomet Manufacturing Corp. | Method and apparatus for application of a fluid |
| US8603138B2 (en) * | 2006-10-04 | 2013-12-10 | Ethicon Endo-Surgery, Inc. | Use of an adhesive to treat intraluminal bleeding |
| US7914511B2 (en) * | 2006-10-18 | 2011-03-29 | Ethicon Endo-Surgery, Inc. | Use of biosurgical adhesive as bulking agent |
| US7749235B2 (en) * | 2006-10-20 | 2010-07-06 | Ethicon Endo-Surgery, Inc. | Stomach invagination method and apparatus |
| US7441973B2 (en) * | 2006-10-20 | 2008-10-28 | Ethicon Endo-Surgery, Inc. | Adhesive applicator |
| US7658305B2 (en) * | 2006-10-25 | 2010-02-09 | Ethicon Endo-Surgery, Inc. | Adhesive applier with articulating tip |
| US7892250B2 (en) | 2006-11-01 | 2011-02-22 | Ethicon Endo-Surgery, Inc. | Use of biosurgical adhesive on inflatable device for gastric restriction |
| US8876844B2 (en) * | 2006-11-01 | 2014-11-04 | Ethicon Endo-Surgery, Inc. | Anastomosis reinforcement using biosurgical adhesive and device |
| US7833216B2 (en) * | 2006-11-08 | 2010-11-16 | Ethicon Endo-Surgery, Inc. | Fluid plunger adhesive dispenser |
| EP2124716A4 (en) * | 2007-02-20 | 2013-01-16 | Renew Medical | FECAL INCONTINENCE DEVICE, KIT AND METHOD |
| WO2008102340A2 (en) * | 2007-02-20 | 2008-08-28 | Svip 1 Llc | Kits and methods for determining colon cleanliness |
| US8287566B2 (en) * | 2007-10-26 | 2012-10-16 | Cohera Medical, Inc. | Spray devices and methods |
| US8518272B2 (en) * | 2008-04-04 | 2013-08-27 | Biomet Biologics, Llc | Sterile blood separating system |
| US8182769B2 (en) | 2008-04-04 | 2012-05-22 | Biomet Biologics, Llc | Clean transportation system |
| WO2009137438A2 (en) | 2008-05-06 | 2009-11-12 | Wilson-Cook Medical Inc. | Apparatus and methods for delivering therapeutic agents |
| AU2009330505A1 (en) | 2008-12-23 | 2011-06-30 | Cook Medical Technologies Llc | Apparatus and methods for containing and delivering therapeutic agents |
| RU2406153C2 (ru) * | 2009-02-25 | 2010-12-10 | Армен Арменакович Акопян | Торговый аппарат аэрозольных смесей |
| US9101744B2 (en) | 2009-05-29 | 2015-08-11 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
| US8118777B2 (en) | 2009-05-29 | 2012-02-21 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
| US8608642B2 (en) * | 2010-02-25 | 2013-12-17 | Ethicon Endo-Surgery, Inc. | Methods and devices for treating morbid obesity using hydrogel |
| US20120000935A1 (en) * | 2010-06-30 | 2012-01-05 | E. I. Du Pont De Nemours And Company | Self-contained hand held yoke-connected device for dispensng a two-part adhesive aerosol |
| US8678238B2 (en) * | 2010-06-30 | 2014-03-25 | Actamax Surgical Materials, Llc | Self-contained hand-held yoke-connected device for dispensing a two-part adhesive aerosol |
| US20130245576A1 (en) * | 2012-03-13 | 2013-09-19 | Nordson Corporation | Applicator spray nozzles with pressure relief |
| EP2722008B1 (de) * | 2012-10-16 | 2018-01-17 | Erbe Elektromedizin GmbH | Düse zur Zufuhr von biologischem Material, insbesondere Zellen, medizinische Vorrichtung mit einer derartigen Düse, Verwendung einer Düse, Verfahren zum Mischen von Fluiden und Gerät |
| US9867931B2 (en) | 2013-10-02 | 2018-01-16 | Cook Medical Technologies Llc | Therapeutic agents for delivery using a catheter and pressure source |
| US11931227B2 (en) | 2013-03-15 | 2024-03-19 | Cook Medical Technologies Llc | Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding |
| IL230151A0 (en) | 2013-12-24 | 2014-09-30 | Omrix Biopharmaceuticals Ltd | One-component fibrin glue containing a polymerization inhibitor |
| EP2907582B1 (de) * | 2014-02-17 | 2017-09-06 | Erbe Elektromedizin GmbH | Verfahren und Düse zum Mischen und Versprühen von medizinischen Fluiden |
| IL231792A0 (en) | 2014-03-27 | 2014-08-31 | Omrix Biopharmaceuticals Ltd | Device and method for the preparation and administration of one-component fibrin glue |
| EP3125774B1 (en) | 2014-04-04 | 2020-05-27 | HyperBranch Medical Technology, Inc. | Extended tip spray applicator for two-component surgical selant, and methods of use thereof |
| US11202848B2 (en) | 2017-03-08 | 2021-12-21 | Baxter International Inc. | Surgical adhesive able to glue in wet conditions |
| US10912859B2 (en) | 2017-03-08 | 2021-02-09 | Baxter International Inc. | Additive able to provide underwater adhesion |
| BR102017008027B1 (pt) * | 2017-04-18 | 2022-04-19 | Cristália Produtos Químicos Farmacêuticos Ltda | Processo de obtenção de biopolímero de fibrina, meios de aplicação do referido biopolímero de fibrina, e processo de aplicação do referido biopolímero de fibrina |
| WO2021247850A2 (en) | 2020-06-05 | 2021-12-09 | Cook Medical Technologies Llc | Medical scopes for delivering therapeutic agents |
| US20240082857A1 (en) * | 2021-01-18 | 2024-03-14 | Bonsens Ab | A swirl nozzle and methods of fabricating the same |
| JP2024518062A (ja) * | 2021-05-10 | 2024-04-24 | ボストン サイエンティフィック サイムド，インコーポレイテッド | 薬剤送達装置およびそれを使用する方法 |
| US12496429B2 (en) | 2022-10-18 | 2025-12-16 | Cook Medical Technologies Llc | Systems and methods for delivering pressurized fluid to a target site alone or in conjunction with therapeutic agents |
| EP4434474A1 (de) * | 2023-03-23 | 2024-09-25 | Erbe Elektromedizin GmbH | Instrument, system und verfahren zum versprühen von flüssigkeiten |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3223083A (en) | 1960-09-09 | 1965-12-14 | President And Directors Of Geo | Method for adhesively securing together skin and other soft tissue and bone |
| GB1162790A (en) * | 1968-07-19 | 1969-08-27 | Andre Passe | Atomizing Apparatus for the Treatment of Wounds |
| US3577516A (en) | 1969-12-02 | 1971-05-04 | Nat Patent Dev Corp | Preparation of spray on bandage |
| JPS5413975U (enExample) * | 1977-06-30 | 1979-01-29 | ||
| US4381008A (en) * | 1978-09-08 | 1983-04-26 | Johnson & Johnson | Methods of improving surface characteristics of extruded thermoplastic tubing and products produced thereby |
| AT366916B (de) | 1980-04-02 | 1982-05-25 | Immuno Ag | Vorrichtung zur applikation eines gewebeklebstoffes auf basis von menschlichen oder tierischenproteinen |
| AT379311B (de) | 1984-03-29 | 1985-12-27 | Immuno Ag | Vorrichtung zur applikation eines gewebeklebstoffes |
| JPS6135236A (ja) * | 1984-07-27 | 1986-02-19 | Minoru Atake | 異径部を有する管状体の製造方法 |
| AT382783B (de) | 1985-06-20 | 1987-04-10 | Immuno Ag | Vorrichtung zur applikation eines gewebeklebstoffes |
| JPH0430147Y2 (enExample) * | 1985-10-08 | 1992-07-21 | ||
| DE3725553A1 (de) | 1987-08-01 | 1989-02-09 | Hoechst Ag | Spruehkopf zum applizieren eines mehrkomponentenmaterials |
| US4978336A (en) | 1987-09-29 | 1990-12-18 | Hemaedics, Inc. | Biological syringe system |
| US4874368A (en) | 1988-07-25 | 1989-10-17 | Micromedics, Inc. | Fibrin glue delivery system |
| US4902281A (en) | 1988-08-16 | 1990-02-20 | Corus Medical Corporation | Fibrinogen dispensing kit |
| NZ233609A (en) * | 1989-05-17 | 1992-10-28 | Critikon Inc | Over-the-needle catheter assembly; restriction in catheter tube to limit liquid backflow |
| US5226877A (en) | 1989-06-23 | 1993-07-13 | Epstein Gordon H | Method and apparatus for preparing fibrinogen adhesive from whole blood |
| US5116315A (en) * | 1989-10-03 | 1992-05-26 | Hemaedics, Inc. | Biological syringe system |
| US5368563A (en) * | 1991-12-18 | 1994-11-29 | Micromedics, Inc. | Sprayer assembly for physiologic glue |
| US5336170A (en) | 1992-07-29 | 1994-08-09 | Research Medical, Inc. | Surgical site visualization wand |
| EP0634140B2 (en) | 1992-09-26 | 2004-08-04 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Applicator for tissue adhesive |
| CN1091315A (zh) | 1992-10-08 | 1994-08-31 | E·R·斯奎布父子公司 | 血纤维蛋白封闭剂组合物及其使用方法 |
| JP2741323B2 (ja) * | 1992-12-21 | 1998-04-15 | 株式会社石川製作所 | 生体組織接着剤塗布用チューブ |
| JP3408295B2 (ja) * | 1993-10-05 | 2003-05-19 | 日本炭酸瓦斯株式会社 | 処置剤の自動押圧噴霧供給装置 |
| CA2112093C (en) | 1993-12-21 | 1995-02-21 | John A. Burgener | Parallel path induction nebulizer |
| EP0748240A4 (en) * | 1994-03-18 | 1998-04-29 | St Jude Medical | INTRA-AORTIC BALLOON CATHETERS |
| WO1995031137A1 (de) | 1994-05-18 | 1995-11-23 | Omrix Biopharmaceuticals S.A. | Vorrichtung zum ausgeben eines mehrkomponenten-gewebeklebstoffes |
| DE59509633D1 (de) | 1994-06-28 | 2001-10-31 | Aventis Behring Gmbh | Vorrichtung zum Versprühen eines Gemischs aus zwei Komponenten |
| JP2789298B2 (ja) * | 1994-07-08 | 1998-08-20 | 株式会社石川製作所 | 生体組織接着剤塗布用チューブ |
| US5605541A (en) * | 1994-12-07 | 1997-02-25 | E. R. Squibb And Sons, Inc. | Fibrin sealant applicatoor |
| DK0800361T3 (da) * | 1994-12-28 | 1999-11-08 | Omrix Biopharm Sa | Indretning til påføring af én eller flere fluider |
| JPH11506649A (ja) * | 1995-06-06 | 1999-06-15 | クウォンティック バイオメディカル パートナーズ | 傷シーラント調製物並びに適用デバイス及び方法 |
| JP3024765U (ja) * | 1995-11-17 | 1996-05-31 | 株式会社八光電機製作所 | 二薬液混合噴霧ノズル |
| NZ325580A (en) * | 1995-12-07 | 2000-03-27 | Bristol Myers Squibb Co | A device for applying a mixture of two liquid components through a nozzle having outlets in a straight line |
| US5759169A (en) | 1996-03-13 | 1998-06-02 | New York Blood Center Inc. | Fibrin sealant glue-gun |
| US5759171A (en) | 1996-09-27 | 1998-06-02 | Thermogenesis Corp. | Sprayer for fibrin glue |
-
1997
- 1997-11-14 CA CA002271738A patent/CA2271738C/en not_active Expired - Fee Related
- 1997-11-14 US US08/970,291 patent/US6454786B1/en not_active Expired - Lifetime
- 1997-11-14 ES ES97946656T patent/ES2284186T3/es not_active Expired - Lifetime
- 1997-11-14 NZ NZ335751A patent/NZ335751A/xx unknown
- 1997-11-14 CA CA002583144A patent/CA2583144C/en not_active Expired - Fee Related
- 1997-11-14 IL IL12991697A patent/IL129916A0/xx unknown
- 1997-11-14 DE DE69737531T patent/DE69737531T2/de not_active Expired - Lifetime
- 1997-11-14 DK DK97946656T patent/DK0951311T3/da active
- 1997-11-14 AT AT97946656T patent/ATE357946T1/de not_active IP Right Cessation
- 1997-11-14 PT PT97946656T patent/PT951311E/pt unknown
- 1997-11-14 BR BR9713070-2A patent/BR9713070A/pt not_active Application Discontinuation
- 1997-11-14 EP EP97946656A patent/EP0951311B1/en not_active Expired - Lifetime
- 1997-11-14 AU AU51782/98A patent/AU721371B2/en not_active Ceased
- 1997-11-14 JP JP52279398A patent/JP4116083B2/ja not_active Expired - Fee Related
- 1997-11-14 WO PCT/US1997/020653 patent/WO1998020931A1/en not_active Ceased
-
1999
- 1999-05-14 NO NO19992342A patent/NO992342L/no not_active Application Discontinuation
- 1999-07-21 US US09/358,078 patent/US6206905B1/en not_active Expired - Fee Related
-
2007
- 2007-05-21 JP JP2007134424A patent/JP2007307385A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DK0951311T3 (da) | 2007-07-09 |
| AU5178298A (en) | 1998-06-03 |
| NZ335751A (en) | 2001-01-26 |
| CA2271738C (en) | 2008-06-03 |
| EP0951311B1 (en) | 2007-03-28 |
| AU721371B2 (en) | 2000-06-29 |
| EP0951311A4 (en) | 2000-11-08 |
| US6454786B1 (en) | 2002-09-24 |
| ATE357946T1 (de) | 2007-04-15 |
| CA2583144A1 (en) | 1998-05-22 |
| JP4116083B2 (ja) | 2008-07-09 |
| DE69737531T2 (de) | 2008-01-31 |
| IL129916A0 (en) | 2000-02-29 |
| NO992342L (no) | 1999-07-06 |
| EP0951311A1 (en) | 1999-10-27 |
| BR9713070A (pt) | 2000-04-11 |
| CA2583144C (en) | 2009-03-10 |
| DE69737531D1 (de) | 2007-05-10 |
| JP2007307385A (ja) | 2007-11-29 |
| US6206905B1 (en) | 2001-03-27 |
| CA2271738A1 (en) | 1998-05-22 |
| JP2001505787A (ja) | 2001-05-08 |
| NO992342D0 (no) | 1999-05-14 |
| WO1998020931A1 (en) | 1998-05-22 |
| ES2284186T3 (es) | 2007-11-01 |
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