BR9713070A - Dispositivos e processos para aplicação de uma mistura de dois ou mais componentes lìquidos para formar um biomaterial. - Google Patents

Dispositivos e processos para aplicação de uma mistura de dois ou mais componentes lìquidos para formar um biomaterial.

Info

Publication number
BR9713070A
BR9713070A BR9713070-2A BR9713070A BR9713070A BR 9713070 A BR9713070 A BR 9713070A BR 9713070 A BR9713070 A BR 9713070A BR 9713070 A BR9713070 A BR 9713070A
Authority
BR
Brazil
Prior art keywords
biomaterial
components
air flow
novel
minute
Prior art date
Application number
BR9713070-2A
Other languages
English (en)
Inventor
Niels Erik Holm
Steven Linnebjerg
Richard Cornwell
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of BR9713070A publication Critical patent/BR9713070A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/08—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/08—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point
    • B05B7/0876—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point to form parallel jets constituted by a liquid or a mixture containing a liquid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A61B2017/00495—Surgical glue applicators for two-component glue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Surgical Instruments (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Nozzles (AREA)

Abstract

"DISPOSITIVOS E PROCESSOS PARA APLICAçãO DE UMA MISTURA DE DOIS OU MAIS COMPONENTES LìQUIDOS PARA FORMAR UM BIOMATERIAL". Trata-se de novos processos e dispositivos, que proporcionam uma mistura acentuada, e aplicação de dois componentes líquidos para formar um biomaterial com aerossóis minimizados, são obtidos usando vazões de ar abaixo de cerca de 1,25 litros/minuto, em combinação com uma razão de vazão de ar para vazão total de líquidos de cerca de 150:1 a cerca de 1.500:1. De preferência, a vazão de ar está abaixo de cerca de 1 litro/minuto e a razão de vazão de ar para a vazão total de líquido é de cerca de 200:1 a cerca de 1.200:1. Os parâmetros são idealmente adequados para a aplicação por aspersão de componentes que formam um selador cirúrgico em vazões de líquido abaixo de 1,9 ml/minuto, os novos processos envolvendo a mistura desses componentes na superfície de saída de uma ponta ou bocal de aspersão (14), novas pontas de aspersão (14), aplicadores de biomaterial e processos de produção desses aplicadores.
BR9713070-2A 1996-11-15 1997-11-14 Dispositivos e processos para aplicação de uma mistura de dois ou mais componentes lìquidos para formar um biomaterial. BR9713070A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3094296P 1996-11-15 1996-11-15
US08/970,291 US6454786B1 (en) 1996-11-15 1997-11-14 Devices and methods for applying a mixture of two or more liquid components to form a biomaterial
PCT/US1997/020653 WO1998020931A1 (en) 1996-11-15 1997-11-14 Devices and methods for applying a mixture of two or more liquid components to form a biomaterial

Publications (1)

Publication Number Publication Date
BR9713070A true BR9713070A (pt) 2000-04-11

Family

ID=26706614

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9713070-2A BR9713070A (pt) 1996-11-15 1997-11-14 Dispositivos e processos para aplicação de uma mistura de dois ou mais componentes lìquidos para formar um biomaterial.

Country Status (15)

Country Link
US (2) US6454786B1 (pt)
EP (1) EP0951311B1 (pt)
JP (2) JP4116083B2 (pt)
AT (1) ATE357946T1 (pt)
AU (1) AU721371B2 (pt)
BR (1) BR9713070A (pt)
CA (2) CA2271738C (pt)
DE (1) DE69737531T2 (pt)
DK (1) DK0951311T3 (pt)
ES (1) ES2284186T3 (pt)
IL (1) IL129916A0 (pt)
NO (1) NO992342L (pt)
NZ (1) NZ335751A (pt)
PT (1) PT951311E (pt)
WO (1) WO1998020931A1 (pt)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000062828A1 (en) 1996-04-30 2000-10-26 Medtronic, Inc. Autologous fibrin sealant and method for making the same
DE19781869T1 (de) * 1996-04-30 2000-03-16 Medtronic Inc Verfahren zur Herstellung eines autologen Fibrin-Blutstillungsmittels
WO2000015117A1 (en) * 1998-09-17 2000-03-23 Focal, Inc. Self-cleaning fluid delivery device for medical applications
US6921380B1 (en) * 1998-10-01 2005-07-26 Baxter International Inc. Component mixing catheter
AU764347B2 (en) * 1998-12-02 2003-08-14 Vivolution A/S Spray delivery of cells
NZ515586A (en) * 1999-06-01 2004-02-27 Bristol Myers Squibb Co Fibrin polymer structure
CA2316554C (en) * 1999-08-25 2007-10-23 Bristol-Myers Squibb Company Applicator and electro-mechanical applicator drive system
US7544177B2 (en) 2002-01-24 2009-06-09 The Regents Of The University Of California Aerosol device to deliver bioactive agent
US7217254B2 (en) * 2002-09-20 2007-05-15 Genzyme Corporation Multi-pressure biocompatible agent delivery device and method
US7077339B2 (en) * 2003-02-03 2006-07-18 Biomet, Inc. Spray applicator
US20040254528A1 (en) * 2003-06-12 2004-12-16 Adams Daniel O. Catheter with removable wire lumen segment
US7490738B2 (en) * 2004-10-01 2009-02-17 Angiotech Pharmaceuticals (Us), Inc. Mixing and dispensing fluid components of a multicomponent composition
US7537174B2 (en) * 2005-01-12 2009-05-26 Baxter International Inc. Hand triggered tissue sealant spray apparatus and system
US7611494B2 (en) * 2005-02-08 2009-11-03 Confluent Surgical, Inc. Spray for fluent materials
ES2380356T3 (es) 2005-02-18 2012-05-10 Tyco Healthcare Group Lp Catéter de intercambio rápido
US7766900B2 (en) * 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
US8603138B2 (en) * 2006-10-04 2013-12-10 Ethicon Endo-Surgery, Inc. Use of an adhesive to treat intraluminal bleeding
US7914511B2 (en) * 2006-10-18 2011-03-29 Ethicon Endo-Surgery, Inc. Use of biosurgical adhesive as bulking agent
US7441973B2 (en) * 2006-10-20 2008-10-28 Ethicon Endo-Surgery, Inc. Adhesive applicator
US7749235B2 (en) * 2006-10-20 2010-07-06 Ethicon Endo-Surgery, Inc. Stomach invagination method and apparatus
US7658305B2 (en) * 2006-10-25 2010-02-09 Ethicon Endo-Surgery, Inc. Adhesive applier with articulating tip
US8876844B2 (en) * 2006-11-01 2014-11-04 Ethicon Endo-Surgery, Inc. Anastomosis reinforcement using biosurgical adhesive and device
US7892250B2 (en) 2006-11-01 2011-02-22 Ethicon Endo-Surgery, Inc. Use of biosurgical adhesive on inflatable device for gastric restriction
US7833216B2 (en) * 2006-11-08 2010-11-16 Ethicon Endo-Surgery, Inc. Fluid plunger adhesive dispenser
WO2008102341A2 (en) * 2007-02-20 2008-08-28 Svip 3 Llc Fecal incontinence device, kit and method
WO2008102340A2 (en) * 2007-02-20 2008-08-28 Svip 1 Llc Kits and methods for determining colon cleanliness
US8287566B2 (en) * 2007-10-26 2012-10-16 Cohera Medical, Inc. Spray devices and methods
US8182769B2 (en) 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US9839772B2 (en) 2008-05-06 2017-12-12 Cook Medical Technologies Llc Apparatus and methods for delivering therapeutic agents
EP2375960B1 (en) 2008-12-23 2018-10-31 Cook Medical Technologies LLC Apparatus for containing and delivering therapeutic agents
US8118777B2 (en) 2009-05-29 2012-02-21 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
US9101744B2 (en) 2009-05-29 2015-08-11 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
US8608642B2 (en) * 2010-02-25 2013-12-17 Ethicon Endo-Surgery, Inc. Methods and devices for treating morbid obesity using hydrogel
US8678238B2 (en) * 2010-06-30 2014-03-25 Actamax Surgical Materials, Llc Self-contained hand-held yoke-connected device for dispensing a two-part adhesive aerosol
US20120000935A1 (en) * 2010-06-30 2012-01-05 E. I. Du Pont De Nemours And Company Self-contained hand held yoke-connected device for dispensng a two-part adhesive aerosol
US20130245576A1 (en) * 2012-03-13 2013-09-19 Nordson Corporation Applicator spray nozzles with pressure relief
EP2722008B1 (de) * 2012-10-16 2018-01-17 Erbe Elektromedizin GmbH Düse zur Zufuhr von biologischem Material, insbesondere Zellen, medizinische Vorrichtung mit einer derartigen Düse, Verwendung einer Düse, Verfahren zum Mischen von Fluiden und Gerät
US11931227B2 (en) 2013-03-15 2024-03-19 Cook Medical Technologies Llc Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding
US9867931B2 (en) 2013-10-02 2018-01-16 Cook Medical Technologies Llc Therapeutic agents for delivery using a catheter and pressure source
IL230151A0 (en) 2013-12-24 2014-09-30 Omrix Biopharmaceuticals Ltd One-component fibrin glue containing a polymerization inhibitor
PL2907582T3 (pl) * 2014-02-17 2018-02-28 Erbe Elektromedizin Gmbh Sposób i dysza do mieszania i rozpryskiwania cieczy medycznych
IL231792A0 (en) 2014-03-27 2014-08-31 Omrix Biopharmaceuticals Ltd Device and method for the preparation and administration of one-component fibrin glue
EP3125774B1 (en) 2014-04-04 2020-05-27 HyperBranch Medical Technology, Inc. Extended tip spray applicator for two-component surgical selant, and methods of use thereof
US10912859B2 (en) 2017-03-08 2021-02-09 Baxter International Inc. Additive able to provide underwater adhesion
US11202848B2 (en) 2017-03-08 2021-12-21 Baxter International Inc. Surgical adhesive able to glue in wet conditions
BR102017008027B1 (pt) * 2017-04-18 2022-04-19 Cristália Produtos Químicos Farmacêuticos Ltda Processo de obtenção de biopolímero de fibrina, meios de aplicação do referido biopolímero de fibrina, e processo de aplicação do referido biopolímero de fibrina
US20220355024A1 (en) * 2021-05-10 2022-11-10 Boston Scientific Scimed, Inc. Agent delivery devices and methods of using the same

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3223083A (en) 1960-09-09 1965-12-14 President And Directors Of Geo Method for adhesively securing together skin and other soft tissue and bone
GB1162790A (en) * 1968-07-19 1969-08-27 Andre Passe Atomizing Apparatus for the Treatment of Wounds
US3577516A (en) 1969-12-02 1971-05-04 Nat Patent Dev Corp Preparation of spray on bandage
JPS5413975U (pt) * 1977-06-30 1979-01-29
US4381008A (en) * 1978-09-08 1983-04-26 Johnson & Johnson Methods of improving surface characteristics of extruded thermoplastic tubing and products produced thereby
AT366916B (de) 1980-04-02 1982-05-25 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes auf basis von menschlichen oder tierischenproteinen
AT379311B (de) * 1984-03-29 1985-12-27 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
JPS6135236A (ja) * 1984-07-27 1986-02-19 Minoru Atake 異径部を有する管状体の製造方法
AT382783B (de) 1985-06-20 1987-04-10 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
JPH0430147Y2 (pt) * 1985-10-08 1992-07-21
DE3725553A1 (de) 1987-08-01 1989-02-09 Hoechst Ag Spruehkopf zum applizieren eines mehrkomponentenmaterials
US4978336A (en) 1987-09-29 1990-12-18 Hemaedics, Inc. Biological syringe system
US4874368A (en) 1988-07-25 1989-10-17 Micromedics, Inc. Fibrin glue delivery system
US4902281A (en) 1988-08-16 1990-02-20 Corus Medical Corporation Fibrinogen dispensing kit
NZ233609A (en) * 1989-05-17 1992-10-28 Critikon Inc Over-the-needle catheter assembly; restriction in catheter tube to limit liquid backflow
US5226877A (en) 1989-06-23 1993-07-13 Epstein Gordon H Method and apparatus for preparing fibrinogen adhesive from whole blood
US5116315A (en) * 1989-10-03 1992-05-26 Hemaedics, Inc. Biological syringe system
US5368563A (en) * 1991-12-18 1994-11-29 Micromedics, Inc. Sprayer assembly for physiologic glue
US5336170A (en) 1992-07-29 1994-08-09 Research Medical, Inc. Surgical site visualization wand
ES2130412T5 (es) 1992-09-26 2005-03-16 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Aplicador de adhesivo destinado para tejidos.
CN1091315A (zh) 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
JP2741323B2 (ja) * 1992-12-21 1998-04-15 株式会社石川製作所 生体組織接着剤塗布用チューブ
JP3408295B2 (ja) * 1993-10-05 2003-05-19 日本炭酸瓦斯株式会社 処置剤の自動押圧噴霧供給装置
CA2112093C (en) 1993-12-21 1995-02-21 John A. Burgener Parallel path induction nebulizer
WO1995025560A1 (en) * 1994-03-18 1995-09-28 St. Jude Medical, Inc. Intra-aortic balloon catheters
WO1995031137A1 (de) 1994-05-18 1995-11-23 Omrix Biopharmaceuticals S.A. Vorrichtung zum ausgeben eines mehrkomponenten-gewebeklebstoffes
ES2163460T3 (es) 1994-06-28 2002-02-01 Aventis Behring Gmbh Dispositivo para pulverizar una mezcla de dos componentes.
JP2789298B2 (ja) * 1994-07-08 1998-08-20 株式会社石川製作所 生体組織接着剤塗布用チューブ
US5605541A (en) 1994-12-07 1997-02-25 E. R. Squibb And Sons, Inc. Fibrin sealant applicatoor
WO1996019940A1 (en) 1994-12-28 1996-07-04 Omrix Biopharmaceuticals S.A. Device for applying one or several fluids
WO1996039212A2 (en) 1995-06-06 1996-12-12 Quantic Biomedical Partners Wound sealant preparation and application device and method
JP3024765U (ja) * 1995-11-17 1996-05-31 株式会社八光電機製作所 二薬液混合噴霧ノズル
DK0865300T3 (da) * 1995-12-07 2004-12-06 Bristol Myers Squibb Co System til at afgive en blanding af to væskekomponenter
US5759169A (en) 1996-03-13 1998-06-02 New York Blood Center Inc. Fibrin sealant glue-gun
US5759171A (en) 1996-09-27 1998-06-02 Thermogenesis Corp. Sprayer for fibrin glue

Also Published As

Publication number Publication date
DE69737531D1 (de) 2007-05-10
CA2583144C (en) 2009-03-10
DE69737531T2 (de) 2008-01-31
CA2271738C (en) 2008-06-03
CA2583144A1 (en) 1998-05-22
JP4116083B2 (ja) 2008-07-09
US6454786B1 (en) 2002-09-24
EP0951311B1 (en) 2007-03-28
ES2284186T3 (es) 2007-11-01
NO992342L (no) 1999-07-06
JP2001505787A (ja) 2001-05-08
EP0951311A4 (en) 2000-11-08
EP0951311A1 (en) 1999-10-27
AU5178298A (en) 1998-06-03
IL129916A0 (en) 2000-02-29
AU721371B2 (en) 2000-06-29
CA2271738A1 (en) 1998-05-22
DK0951311T3 (da) 2007-07-09
JP2007307385A (ja) 2007-11-29
PT951311E (pt) 2007-06-05
US6206905B1 (en) 2001-03-27
ATE357946T1 (de) 2007-04-15
NZ335751A (en) 2001-01-26
WO1998020931A1 (en) 1998-05-22
NO992342D0 (no) 1999-05-14

Similar Documents

Publication Publication Date Title
BR9713070A (pt) Dispositivos e processos para aplicação de uma mistura de dois ou mais componentes lìquidos para formar um biomaterial.
CA2152749A1 (en) Apparatus for spraying a mixture of two components
DE69734557D1 (de) Sprühvorrichtung zum aufbringen von gewebeklebstoff
ATA41494A (de) Vorrichtung zur applikation eines mehrkomponenten-gewebeklebstoffes
ATE300971T1 (de) Gasgetriebene sprühvorrichtung für gemischte fibrinkleber
ATE208237T1 (de) Verfahren und vorrichtung zur gleichzeitigen dispergierung und zerstäubung von mindestens zwei flüssigkeiten
BR9714615A (pt) Dispositivo de atomização de queda de rayleigh e processos de fabricação de dispositvos de atomização de queda de 05 rayleigh
GR3008295T3 (pt)
TW200626203A (en) Method for spraying a medium and spraying nozzle
BR9506946A (pt) Bocal pulverizador de fluido duplo e processo para produzir uma pulverizaçao atomatizada de um material em suspensao
ATE196996T1 (de) Verfahren und vorrichtung zur verdüsung von flüssigem löschmittel in stationären löschanlagen
DK1059957T3 (da) Turbulens-blandingshoved til en applikator for vævsklæbemiddel og forstöverhoved hertil
BR9713640A (pt) Combinação de um dispositivo de pulverização incluindo um reservatório contendo uma composição de limpeza.
EP0865300A4 (en) METHOD OF APPLYING A MIXTURE OF TWO LIQUID COMPONENTS
DE69937741D1 (de) Auftragsspitze für ein dichtmittel und auftrageverfahren
MXPA04000688A (es) Equipo de pulverizacion de baja presion asistido por aire que tiene una tobera de pulverizacion meojorada.
DE60214326D1 (de) Verfahren zur Verwendung von wässrigen Mehrkomponentbeschichtungszusammensetzungen
AU2821589A (en) A method and equipment for microatomizing liquids, preferably melts
BR9914532A (pt) Processo de preparação de uma solução para pulverização nasal que contém um ou vários hormÈnios sexuais e uma ciclodextrina
ES2083857T3 (es) Frasco dotado de una embocadura reductora y su aplicacion a la dispersion de un liquido de baja viscosidad.

Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
B09B Patent application refused [chapter 9.2 patent gazette]