PT94813A - Processo para a preparacao de peptidos epo de eritropoietina e de anticorpos contra eles - Google Patents

Processo para a preparacao de peptidos epo de eritropoietina e de anticorpos contra eles

Info

Publication number
PT94813A
PT94813A PT94813A PT9481390A PT94813A PT 94813 A PT94813 A PT 94813A PT 94813 A PT94813 A PT 94813A PT 9481390 A PT9481390 A PT 9481390A PT 94813 A PT94813 A PT 94813A
Authority
PT
Portugal
Prior art keywords
epo
antibodies
epitope
relates
peptides
Prior art date
Application number
PT94813A
Other languages
English (en)
Other versions
PT94813B (pt
Inventor
Mathias Dr Fibi
Werner Dr Stueber
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of PT94813A publication Critical patent/PT94813A/pt
Publication of PT94813B publication Critical patent/PT94813B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT94813A 1989-07-26 1990-07-25 Processo para a preparacao de peptidos epo de eritropoietina e de anticorpos contra eles PT94813B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3924746A DE3924746A1 (de) 1989-07-26 1989-07-26 Erythropoietin (epo)-peptide und dagegen gerichtete antikoerper

Publications (2)

Publication Number Publication Date
PT94813A true PT94813A (pt) 1991-03-20
PT94813B PT94813B (pt) 1997-04-30

Family

ID=6385895

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94813A PT94813B (pt) 1989-07-26 1990-07-25 Processo para a preparacao de peptidos epo de eritropoietina e de anticorpos contra eles

Country Status (13)

Country Link
US (2) US5106954A (pt)
EP (1) EP0410246B1 (pt)
JP (1) JP3155002B2 (pt)
KR (1) KR0175657B1 (pt)
AT (1) ATE161577T1 (pt)
AU (1) AU648506B2 (pt)
CA (1) CA2021912C (pt)
DE (2) DE3924746A1 (pt)
DK (1) DK0410246T3 (pt)
ES (1) ES2111524T3 (pt)
GR (1) GR3026096T3 (pt)
IE (1) IE902707A1 (pt)
PT (1) PT94813B (pt)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6932968B1 (en) * 1989-07-26 2005-08-23 Dade Behring Marburg Gmbh Erythropoietin (EPO) peptides and antibodies directed against these
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
GB2270695B (en) * 1992-09-18 1996-06-05 Oxford Res Support Co Ltd Antibodies that activate plasminogen in the manner of streptokinase
US5830851A (en) * 1993-11-19 1998-11-03 Affymax Technologies N.V. Methods of administering peptides that bind to the erythropoietin receptor
US5773569A (en) * 1993-11-19 1998-06-30 Affymax Technologies N.V. Compounds and peptides that bind to the erythropoietin receptor
HUP9901069A2 (hu) * 1995-06-07 1999-07-28 Affymax Technologies, N.V. Az eritropoietin receptorhoz kötődő vegyületek és peptidek
KR100400637B1 (ko) * 1996-02-06 2004-03-10 씨제이 주식회사 생물학적으로유용한펩타이드
US5952226A (en) * 1996-11-05 1999-09-14 Modex Therapeutiques Hypoxia responsive EPO producing cells
TR200001580T2 (tr) * 1997-12-03 2000-12-21 Roche Diagnostics Gmbh Spesifik etkinliği yüksek eritropoyetin
KR100524041B1 (ko) * 1999-05-07 2005-10-27 제넨테크, 인크. 신규 침팬지 에리쓰로포이에틴 (chepo) 폴리펩티드 및 이를 코딩하는 핵산
IL145785A0 (en) * 1999-05-07 2002-07-25 Genentech Inc Novel chimpanzee erythropoietin (chepo) polypeptides and nucleic acids encoding the same
US6831060B2 (en) 1999-05-07 2004-12-14 Genentech, Inc. Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
US6703480B1 (en) 1999-11-24 2004-03-09 Palani Balu Peptide dimers as agonists of the erythropoientin (EPO) receptor, and associated methods of synthesis and use
US7312089B2 (en) * 2000-04-05 2007-12-25 Jong Y. Lee Detection of erythropoietin and erythropoietin receptor
US20050100991A1 (en) * 2001-04-12 2005-05-12 Human Genome Sciences, Inc. Albumin fusion proteins
CA2405557C (en) 2000-04-12 2013-09-24 Human Genome Sciences, Inc. Albumin fusion proteins
CA2437272A1 (en) * 2001-02-06 2002-08-15 Merck Patent Gesellschaft Mit Beschraenkter Haftung Modified erythropoietin (epo) with reduced immunogenicity
WO2002070009A1 (fr) * 2001-02-27 2002-09-12 Yasuda, Yoshiko Medicaments preventifs/curatifs pour cicatrices hypertrophiques, cheloides et maladies arthritiques chroniques
CA2446739A1 (en) * 2001-05-25 2002-12-05 Human Genome Sciences, Inc. Chemokine beta-1 fusion proteins
US7045546B2 (en) * 2001-07-26 2006-05-16 Tagra Biotechnologies Ltd. Stabilized derivatives of ascorbic acid-3-phosphate
US6930086B2 (en) 2001-09-25 2005-08-16 Hoffmann-La Roche Inc. Diglycosylated erythropoietin
WO2004099231A2 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
AU2002364587A1 (en) * 2001-12-21 2003-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
EP2261250B1 (en) * 2001-12-21 2015-07-01 Human Genome Sciences, Inc. GCSF-Albumin fusion proteins
PL372862A1 (en) * 2002-08-09 2005-08-08 Merck Patent Gmbh T-cell epitopes in erythropoietin
EP1594530A4 (en) 2003-01-22 2006-10-11 Human Genome Sciences Inc HYBRID PROTEINS OF ALBUMIN
CA2521273A1 (en) * 2003-04-02 2004-10-21 Epimmune Inc. Peptides, polypeptides, and proteins of reduced immunogenicity and methods for their production
US20040266993A1 (en) * 2003-06-30 2004-12-30 Evans Glen A. Non-immunoglobulin binding polypeptides
US7588745B2 (en) * 2004-04-13 2009-09-15 Si Options, Llc Silicon-containing products
US20050255112A1 (en) * 2004-05-17 2005-11-17 Lee Jong Y Compositions and methods for preventing erythropoietin-associated hypertension
MX2007005640A (es) * 2004-11-10 2007-08-14 Aplagen Gmbh Moleculas que promueven la hematopoyesis.
KR20070092706A (ko) * 2004-11-10 2007-09-13 아플라겐 게엠베하 조혈을 촉진하는 분자
US7589063B2 (en) * 2004-12-14 2009-09-15 Aplagen Gmbh Molecules which promote hematopoiesis
EP1848461A2 (en) * 2005-02-16 2007-10-31 Nektar Therapeutics Al, Corporation Conjugates of an epo moiety and a polymer
US8329652B2 (en) * 2005-05-10 2012-12-11 Neoloch Aps Neuritogenic peptides
EP1736481A1 (en) * 2005-05-13 2006-12-27 Charite Universitätsmedizin-Berlin Erythropoietin variants
EP1907417A2 (en) * 2005-06-23 2008-04-09 AplaGen GmbH Supravalent compounds
PT2540309T (pt) 2005-08-05 2017-12-29 Araim Pharmaceuticals Inc Péptidos protectores de tecidos e suas utilizações
WO2007101698A2 (en) * 2006-03-09 2007-09-13 Aplagen Gmbh Modified molecules which promote hematopoiesis
EP2134862A4 (en) * 2007-03-12 2011-04-20 Univ Utah Res Found COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF DIABETIC MICROVASCULAR COMPLICATIONS
SG188161A1 (en) 2008-01-22 2013-03-28 Araim Pharmaceuticals Inc Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
CA2712606A1 (en) 2008-02-08 2009-08-13 Ambrx, Inc. Modified leptin polypeptides and their uses
CN102232085A (zh) 2008-09-26 2011-11-02 Ambrx公司 修饰的动物促红细胞生成素多肽和其用途
KR102233664B1 (ko) * 2012-12-05 2021-04-02 노파르티스 아게 Epo를 표적화하는 항체에 대한 조성물 및 방법
ES2913530T3 (es) 2015-08-12 2022-06-02 Novartis Ag Métodos para tratar trastornos oftálmicos

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56145222A (en) * 1980-04-28 1981-11-11 Toshiyuki Hamaoka Improved antibody and its preparation
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4748018A (en) * 1984-02-07 1988-05-31 Stolle Research & Development Corp. Method of passive immunization of mammals using avian antibody
US4558005A (en) * 1982-09-13 1985-12-10 University Patents, Inc. Monoclonal anti-erythropoietin
US4558006A (en) * 1983-02-04 1985-12-10 Kirin-Amgen, Inc. A.T.C.C. HB8209 and its monoclonal antibody to erythropoietin
NZ210501A (en) * 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
US4703008A (en) * 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
US4677195A (en) * 1985-01-11 1987-06-30 Genetics Institute, Inc. Method for the purification of erythropoietin and erythropoietin compositions

Also Published As

Publication number Publication date
JP3155002B2 (ja) 2001-04-09
DE59010787D1 (de) 1998-02-05
US5106954A (en) 1992-04-21
US5712370A (en) 1998-01-27
CA2021912C (en) 2001-11-27
ATE161577T1 (de) 1998-01-15
CA2021912A1 (en) 1991-01-27
KR0175657B1 (ko) 1999-04-01
DE3924746A1 (de) 1991-01-31
EP0410246A1 (de) 1991-01-30
IE902707A1 (en) 1991-02-27
AU648506B2 (en) 1994-04-28
AU5977890A (en) 1991-01-31
KR910002897A (ko) 1991-02-26
EP0410246B1 (de) 1997-12-29
ES2111524T3 (es) 1998-03-16
PT94813B (pt) 1997-04-30
GR3026096T3 (en) 1998-05-29
JPH0381294A (ja) 1991-04-05
DK0410246T3 (da) 1998-08-31

Similar Documents

Publication Publication Date Title
PT94813A (pt) Processo para a preparacao de peptidos epo de eritropoietina e de anticorpos contra eles
ES2062971T3 (es) Peptidos de la cubierta de htlv iii.
WO1996029605A3 (en) Compounds and methods for the dectection of t. cruzi infection
DK0536275T3 (da) Tumorvækstinhibitorer udledt fra væv, fremgangsmåde til deres fremstilling samt anvendelse heraf
ES2082775T3 (es) Anticuerpos de proteinas latentes de papilomavirus humano, sistemas de diagnostico y procedimientos.
IT1197431B (it) Antigene anti-malarico, procedimento per la sua preparazione e vaccino che lo contiene
NO910209L (no) Fremgangsmaate for fremstilling av rekombinante humane anti-cd18-antistoffer.
NO870476D0 (no) Fremgangsmaate for fremstilling av kryss-beskyttende humane monoklonale antistoffpreparater.
DK0725837T3 (da) Adeno-associeret virus - dettes diagnostiske anvendelse ved tidlig abort
DE69504959D1 (de) Humanisierte monoklonale antikörper gegen humanes interleukin - 4
NO873774D0 (no) Monoklonale eller polyklonale antistoffer.
DK172686A (da) Antigen opnaaet ud fra humant vaev, fremgangsmaade til under anvendelse af antigenet at fremstille monoklonale antistoffer til diagnose og behandling af cancer, fremgangsmaade til paavisning af cancer, samt antistoffer mod antigenet
SE9201281D0 (sv) New human monoclonal antibodies, and a method for preparation thereof
OA09026A (en) Method for detecting antibodies to human immunodeficiency virus.
DE3785175D1 (de) A-assoziierte h-antigene, spezifische monoklonale antikoerper und methoden zu deren verwendung zur blutgruppenbestimmung.
SE9602234D0 (sv) A novel diagnostic method utilizing ECP, and reagents to be used in the methods
PT97179A (pt) Processo para a preparacao de anticorpos monoclonias anti-oncostatina m
NO874405L (no) Fremgangsmaate til bestemmelse av naervaer av diagnostisk relevante stoffer, spesielt antistoffer eller antigener etter elisa-metoden ved fotometrisk vurdering.
ZA903854B (en) Diagnostic test for detecting antibodies directed against antigens of one or more related viruses
PT88077A (pt) Anticorpos monoclonais e metodos para o diagnostico de infeccao por phytophthora
BR9305525A (pt) Teste de anticorpos para amilina
NO900092L (no) Et ekspresjonssystem for fremstilling av kimeriske monoklonale antistoffer.
IL83422A (en) Method for the detection of human b lymphotropic virus antibodies
SE8305667L (sv) Adenokarcinomrelaterade nya antigena determinanter och antikroppar som er specifika for dessa, forfarande for deras framstellning samt reagenssystem henforande sig till dem
DK362087D0 (da) Method for a rapid and sensitive detection of early appearing antibodies against retroviruses, as well as igg antibodies against certain retroviruses

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19901019

PC3A Transfer or assignment

Free format text: 19981125 BEHRING DIAGNOSTICS GMBH DE

PD3A Change of proprietorship

Owner name: DADE BEHRING MARBURG GMBH

Effective date: 19981125

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20120123