PT91117A - Processo de preparacao de derivados de piridazinona e de composicoes farmaceuticas que os contem - Google Patents

Processo de preparacao de derivados de piridazinona e de composicoes farmaceuticas que os contem

Info

Publication number
PT91117A
PT91117A PT91117A PT9111789A PT91117A PT 91117 A PT91117 A PT 91117A PT 91117 A PT91117 A PT 91117A PT 9111789 A PT9111789 A PT 9111789A PT 91117 A PT91117 A PT 91117A
Authority
PT
Portugal
Prior art keywords
alkyl
heart
improve
pharmaceutical compositions
compositions containing
Prior art date
Application number
PT91117A
Other languages
English (en)
Other versions
PT91117B (pt
Inventor
James Redpath
Robert Thomas Logan
Robert Gibson Roy
George Mcgarry
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of PT91117A publication Critical patent/PT91117A/pt
Publication of PT91117B publication Critical patent/PT91117B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PT91117A 1988-07-11 1989-07-10 Processo de preparacao de derivados de piridazinona e de composicoes farmaceuticas que os contem PT91117B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88306295 1988-07-11

Publications (2)

Publication Number Publication Date
PT91117A true PT91117A (pt) 1990-02-08
PT91117B PT91117B (pt) 1995-07-06

Family

ID=8200131

Family Applications (1)

Application Number Title Priority Date Filing Date
PT91117A PT91117B (pt) 1988-07-11 1989-07-10 Processo de preparacao de derivados de piridazinona e de composicoes farmaceuticas que os contem

Country Status (16)

Country Link
US (1) US4952571A (pt)
EP (1) EP0350990B1 (pt)
JP (1) JPH0285281A (pt)
KR (1) KR900001691A (pt)
AT (1) ATE128135T1 (pt)
AU (1) AU617489B2 (pt)
CA (1) CA1308413C (pt)
DE (1) DE68924308T2 (pt)
DK (1) DK340889A (pt)
ES (1) ES2080064T3 (pt)
FI (1) FI97295C (pt)
GR (1) GR3018356T3 (pt)
IE (1) IE68680B1 (pt)
NZ (1) NZ229876A (pt)
PT (1) PT91117B (pt)
ZA (1) ZA895087B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL94394A (en) * 1989-05-17 1994-10-21 Nissan Chemical Ind Ltd History of pyridazinone, process for their preparation and preparations for controlling and / or preventing insects, mites, nematodes and mollusks
KR100226053B1 (ko) * 1996-06-18 1999-10-15 권태웅 공장제어 시스템의 비데오 카피어 인터페이스 모듈
US6276721B1 (en) * 2000-03-14 2001-08-21 Simula, Inc. Pivoting seat belt upper anchor point attachment
FR2829977B1 (fr) * 2001-09-24 2003-12-12 Valeo Vision Projecteur d'eclairage ou de signalisation a controleur integre pour vehicule et systeme d'eclairage ou de signalisation equipe d'au moins un tel projecteur
PT3523287T (pt) * 2016-10-04 2021-10-06 Merck Sharp & Dohme Compostos de benzo[b]tiofeno como agonistas de sting
US11312772B2 (en) 2017-08-04 2022-04-26 Merck Sharp & Dohme Corp. Combinations of PD-1 antagonists and benzo [b] thiophene STING agonists for cancer treatment
CA3071538A1 (en) 2017-08-04 2019-02-07 Merck Sharp & Dohme Corp. Benzo[b]thiophene sting agonists for cancer treatment
US11702430B2 (en) 2018-04-03 2023-07-18 Merck Sharp & Dohme Llc Aza-benzothiophene compounds as STING agonists
US10793557B2 (en) 2018-04-03 2020-10-06 Merck Sharp & Dohme Corp. Sting agonist compounds
CN113861161A (zh) * 2020-06-30 2021-12-31 上海海和药物研究开发股份有限公司 一种芳基并芳杂环衍生物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8101067A1 (es) * 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
US4225711A (en) * 1978-10-02 1980-09-30 Schering Corporation Substituted 2-[(methylsulfinyl)acetyl]-3-heterocyclicindoles and their use as immunosuppressants
DE3129447A1 (de) * 1981-07-25 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benztriazole, ihre herstellung und ihre verwendung als arzneimittel"
CA1199027A (en) * 1981-11-12 1986-01-07 Stuart D. Mills Heterocyclic derivatives of pyridazinone, thiadiazinone, oxadiazinone and triazinone
US4666902A (en) * 1983-06-20 1987-05-19 Cassella Aktiengesellschaft Tetrahydropyridazinone derivatives, processes for their preparation and their use
US4647564A (en) * 1984-05-14 1987-03-03 Eli Lilly And Company Inotropic agents
DE3511110A1 (de) * 1985-03-27 1986-10-02 Dr. Karl Thomae Gmbh, 7950 Biberach Neue pyridazinone, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3631085A1 (de) * 1986-09-12 1988-03-24 Boehringer Mannheim Gmbh Heterocyclisch substituierte indolinone, verfahren zu ihrer herstellung, arzneimittel sowie zwischenprodukte

Also Published As

Publication number Publication date
IE68680B1 (en) 1996-07-10
NZ229876A (en) 1991-03-26
ZA895087B (en) 1990-03-28
PT91117B (pt) 1995-07-06
JPH0285281A (ja) 1990-03-26
IE892148L (en) 1990-01-11
FI893345A (fi) 1990-01-12
US4952571A (en) 1990-08-28
FI97295C (fi) 1996-11-25
FI893345A0 (fi) 1989-07-10
KR900001691A (ko) 1990-02-27
DK340889D0 (da) 1989-07-10
GR3018356T3 (en) 1996-03-31
DK340889A (da) 1990-01-12
AU3796789A (en) 1990-01-11
ES2080064T3 (es) 1996-02-01
ATE128135T1 (de) 1995-10-15
AU617489B2 (en) 1991-11-28
DE68924308T2 (de) 1996-04-04
FI97295B (fi) 1996-08-15
DE68924308D1 (de) 1995-10-26
EP0350990B1 (en) 1995-09-20
CA1308413C (en) 1992-10-06
EP0350990A1 (en) 1990-01-17

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Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19980831