PT901384E - Esponjas de polissacarido para cultura e transplante de celulas - Google Patents

Esponjas de polissacarido para cultura e transplante de celulas

Info

Publication number
PT901384E
PT901384E PT97920932T PT97920932T PT901384E PT 901384 E PT901384 E PT 901384E PT 97920932 T PT97920932 T PT 97920932T PT 97920932 T PT97920932 T PT 97920932T PT 901384 E PT901384 E PT 901384E
Authority
PT
Portugal
Prior art keywords
polysacarid
sponges
culture
cell transplantation
mum
Prior art date
Application number
PT97920932T
Other languages
English (en)
Inventor
Smadar Cohen
Lilia Shapiro
Rachel Glicklis
Original Assignee
Ben Gurion Univ Negev Res And
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ben Gurion Univ Negev Res And filed Critical Ben Gurion Univ Negev Res And
Publication of PT901384E publication Critical patent/PT901384E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A61F2/105—Skin implants, e.g. artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/26—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a solid phase from a macromolecular composition or article, e.g. leaching out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/02—Dextran; Derivatives thereof
PT97920932T 1996-05-22 1997-05-21 Esponjas de polissacarido para cultura e transplante de celulas PT901384E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11837696A IL118376A0 (en) 1996-05-22 1996-05-22 Polysaccharide sponges for cell culture and transplantation

Publications (1)

Publication Number Publication Date
PT901384E true PT901384E (pt) 2004-02-27

Family

ID=11068894

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97920932T PT901384E (pt) 1996-05-22 1997-05-21 Esponjas de polissacarido para cultura e transplante de celulas

Country Status (12)

Country Link
US (3) US6425918B1 (pt)
EP (1) EP0901384B1 (pt)
JP (1) JP2000512666A (pt)
AT (1) ATE249251T1 (pt)
AU (1) AU714647B2 (pt)
CA (1) CA2256327C (pt)
DE (1) DE69724780T2 (pt)
DK (1) DK0901384T3 (pt)
ES (1) ES2206707T3 (pt)
IL (1) IL118376A0 (pt)
PT (1) PT901384E (pt)
WO (1) WO1997044070A1 (pt)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2318577B (en) * 1996-10-28 2000-02-02 Johnson & Johnson Medical Solvent dried polysaccharide sponges
WO1999058656A2 (en) * 1998-05-13 1999-11-18 The Regents Of The University Of Michigan Sustained dna delivery from structural matrices
IL124957A0 (en) * 1998-06-16 1999-01-26 Univ Ben Gurion Active ingredient delivery systems and devices based on porous matrices
KR100298846B1 (ko) * 1998-09-24 2003-10-22 한국원자력연구소 중화키토산스폰지또는중화키토산/콜라겐혼합스폰지를이용한인공진피
WO2001036000A1 (en) * 1999-11-15 2001-05-25 Bio Syntech Canada, Inc. Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
DE19957388A1 (de) * 1999-11-24 2001-06-13 Michael Sittinger Chondroinduktive und implantierbare Substrate zur Knorpelheilung und -protektion
JP5089006B2 (ja) * 2000-06-29 2012-12-05 ピラマル ヘルスケア （カナダ） リミテッド 軟骨および他の組織の修復および再生のための組成物および方法
US7214371B1 (en) 2000-09-01 2007-05-08 Ben-Gurion University Of The Negev Research & Development Authority Tissue engineered biografts for repair of damaged myocardium
CA2435491C (en) * 2001-01-31 2010-02-02 Seikagaku Corporation Crosslinked polysaccharide sponge
US7485318B2 (en) * 2001-04-04 2009-02-03 Delsitech Oy Biodegradable carrier and method for preparation thereof
KR20030096381A (ko) * 2001-05-11 2003-12-24 오쏘-맥네일 파머슈티칼 인코퍼레이티드 동물에 사용하기 위한 면역 조절장치
JP2003052395A (ja) * 2001-08-09 2003-02-25 Japan Tissue Engineering:Kk 移植適正判定方法
TWI230619B (en) * 2001-08-16 2005-04-11 Ind Tech Res Inst Method of crosslinking of porous biodegradable polymers
US7494664B2 (en) * 2001-10-25 2009-02-24 Japan Science And Technology Agency Composite biomaterials
US7105580B2 (en) * 2001-12-06 2006-09-12 University Of Washington Porous structures useful for growing living tissue, and methods of manufacture
US20040029266A1 (en) * 2002-08-09 2004-02-12 Emilio Barbera-Guillem Cell and tissue culture device
US20040063206A1 (en) * 2002-09-30 2004-04-01 Rowley Jon A. Programmable scaffold and method for making and using the same
US20040147016A1 (en) * 2002-09-30 2004-07-29 Rowley Jonathan A. Programmable scaffold and methods for making and using the same
KR100539371B1 (ko) * 2002-10-21 2005-12-27 메디칸(주) 인체 세포의 체외배양 방법
US20040126405A1 (en) * 2002-12-30 2004-07-01 Scimed Life Systems, Inc. Engineered scaffolds for promoting growth of cells
WO2004067704A2 (en) * 2003-01-30 2004-08-12 Prochon Biotech Ltd. Freeze-dried fibrin matrices and methods for preparation thereof
KR100984184B1 (ko) * 2003-03-18 2010-09-28 에스케이케미칼주식회사 알긴산 스폰지 및 그의 제조방법
US8007823B2 (en) * 2003-04-03 2011-08-30 Corporation De L'ecole Polytechnique De Montreal Microporous articles comprising biodegradable medical polymers, method of preparation thereof and method of use thereof
JP2006525405A (ja) 2003-05-05 2006-11-09 ベン‐グリオン ユニバーシティ オブ ザ ネゲヴ リサーチ アンド デベロップメント オーソリティ 注入可能な架橋されたポリマー調製物およびその使用
DE10323794A1 (de) * 2003-05-23 2004-12-09 Dr. Suwelack Skin & Health Care Ag Verfahren zur Herstellung von Alginat-haltigen porösen Formkörpern
JP2005046538A (ja) * 2003-07-31 2005-02-24 Jms Co Ltd 医療用多孔質体およびその製造方法
WO2005023323A1 (en) * 2003-09-08 2005-03-17 Fmc Biopolymer As Gelled biopolymer based foam
JP2005080927A (ja) * 2003-09-09 2005-03-31 Jms Co Ltd 医療用多孔質体の製造方法
WO2005026214A1 (ja) * 2003-09-12 2005-03-24 Seikagaku Corporation 多糖擬スポンジ
US20050119704A1 (en) * 2003-11-13 2005-06-02 Peters Nicholas S. Control of cardiac arrhythmias by modification of neuronal conduction within fat pads of the heart
US8073538B2 (en) 2003-11-13 2011-12-06 Cardio Polymers, Inc. Treatment of cardiac arrhythmia by modification of neuronal signaling through fat pads of the heart
US20090169520A1 (en) * 2004-01-09 2009-07-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compounds, Pharmaceutical Compositions and Therapeutic Methods of Preventing and Treating Diseases and Disorders Associated With Amyloid Fibril Formation
US20050272153A1 (en) 2004-01-27 2005-12-08 Zou Xuenong Bone tissue engineering by ex vivo stem cells ongrowth into three-dimensional trabecular metal
WO2005078016A1 (en) * 2004-02-05 2005-08-25 Millipore Corporation Room temperature stable agarose solutions
WO2005078028A1 (en) * 2004-02-05 2005-08-25 Millipore Corporation Method of forming polysaccharide structures
JP4607522B2 (ja) * 2004-08-31 2011-01-05 焼津水産化学工業株式会社 高分子複合体の製造方法及び該製造方法によって得られる高分子複合体、並びに該高分子複合体を用いた動物細胞の培養方法
JP5367266B2 (ja) * 2004-10-12 2013-12-11 エフエムシー バイオポリマー エイエス 自己ゲル化性アルギネート系及びその使用
US7514256B2 (en) 2005-02-11 2009-04-07 Emilio Barbera-Guillem Bioreactor for selectively controlling the molecular diffusion between fluids
US9427496B2 (en) 2005-02-18 2016-08-30 Drexel University Method for creating an internal transport system within tissue scaffolds using computer-aided tissue engineering
US20060239956A1 (en) * 2005-04-26 2006-10-26 Lulu Henson Preparation and use of hydrogels
US20060292690A1 (en) * 2005-06-22 2006-12-28 Cesco Bioengineering Co., Ltd. Method of making cell growth surface
JP2009508596A (ja) 2005-09-19 2009-03-05 ヒストジェニックス コーポレイション 細胞支持基材及びその調製方法
US9132208B2 (en) * 2008-08-07 2015-09-15 Lifenet Health Composition for a tissue repair implant and methods of making the same
US9005646B2 (en) 2005-10-12 2015-04-14 Lifenet Health Compositions for repair of defects in tissues, and methods of making the same
PT2347775T (pt) 2005-12-13 2020-07-14 The President And Fellows Of Harvard College Estruturas em andaime para transplante celular
TWI285100B (en) * 2005-12-27 2007-08-11 Ind Tech Res Inst Surface modification of polysaccharide, the modified polysaccharide, and method of culturing and recovery cells using the same
WO2007103209A2 (en) * 2006-03-01 2007-09-13 Fmc Biopolymer As Gelled composite
US20080124372A1 (en) * 2006-06-06 2008-05-29 Hossainy Syed F A Morphology profiles for control of agent release rates from polymer matrices
US8168215B2 (en) * 2006-06-16 2012-05-01 Fmc Biopolymer As Alginate coated, collagen matrix cellular device, preparative methods, and uses thereof
JP5248492B2 (ja) * 2006-07-14 2013-07-31 エフエムシー バイオポリマー エイエス 低分子量アルギネートを含むヒドロゲルおよびそれから製造されたバイオ構造物
AU2007293055B2 (en) * 2006-09-08 2013-08-01 Cardiopolymers, Inc. Intramyocardial patterning for global cardiac resizing and reshaping
WO2008045506A2 (en) * 2006-10-10 2008-04-17 President And Fellows Of Harvard College Biopolymer structures
US9127254B2 (en) * 2006-12-18 2015-09-08 Ben-Gurion University Of The Negev Research And Development Authority Scaffolding for tissue regeneration or repair
WO2008081463A2 (en) * 2007-01-04 2008-07-10 Hepacore Ltd. Water soluble reactive derivatives of carboxy polysaccharides and fibrinogen conjugates thereof
JP2010520766A (ja) * 2007-03-09 2010-06-17 コーニング インコーポレイテッド 細胞培養用三次元ガムマトリックス、製造方法および使用方法
US20080220526A1 (en) * 2007-03-09 2008-09-11 Ellison Adam J Gum coatings for cell culture, methods of manufacture and methods of use
EP2146667A2 (en) * 2007-04-11 2010-01-27 Henry Ford Health System Cardiac repair, resizing and reshaping using the venous system of the heart
WO2008154033A2 (en) * 2007-06-11 2008-12-18 Symphony Medical, Inc. Cardiac patterning for improving diastolic function
WO2008157318A2 (en) * 2007-06-13 2008-12-24 Fmc Corporation Alginate coated, polysaccharide gel-containing foam composite, preparative methods, and uses thereof
US9770535B2 (en) 2007-06-21 2017-09-26 President And Fellows Of Harvard College Scaffolds for cell collection or elimination
WO2009032158A2 (en) * 2007-08-28 2009-03-12 Fmc Corporation, Inc. Delayed self-gelling alginate systems and uses thereof
IL187707A0 (en) 2007-11-27 2008-11-03 Univ Ben Gurion Alginate scaffold in hepatectomy
JP5690143B2 (ja) 2008-02-13 2015-03-25 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 持続的細胞プログラミング装置
US9370558B2 (en) 2008-02-13 2016-06-21 President And Fellows Of Harvard College Controlled delivery of TLR agonists in structural polymeric devices
WO2009108760A2 (en) 2008-02-26 2009-09-03 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
US20090259210A1 (en) * 2008-04-10 2009-10-15 Sabbah Hani N Method, apparatus and kits for forming structural members within the cardiac venous system
US9198997B2 (en) * 2008-04-24 2015-12-01 Medtronic, Inc. Rehydratable thiolated polysaccharide particles and sponge
CA2721986C (en) 2008-04-24 2017-03-14 Medtronic, Inc. Rehydratable polysaccharide particles and sponge
WO2009132227A1 (en) * 2008-04-24 2009-10-29 Medtronic, Inc. Protective gel based on chitosan and oxidized polysaccharide
EP2313104B2 (en) * 2008-04-24 2020-08-26 Medtronic, Inc Thiolated chitosan gel
WO2009132228A1 (en) * 2008-04-24 2009-10-29 Medtronic, Inc. Chitosan-containing protective composition
US20100159567A1 (en) * 2008-11-07 2010-06-24 Kuehnle Adelheid R Preservation and composition of bioprocess algae for production of lipids, seedstock, and feed
US8735140B2 (en) * 2008-11-07 2014-05-27 Kuehnle Agrosystems, Inc. Preservation and composition of bioprocess algae for production of lipids, seedstock, and feed
US9297005B2 (en) 2009-04-13 2016-03-29 President And Fellows Of Harvard College Harnessing cell dynamics to engineer materials
CA2768552A1 (en) 2009-07-31 2011-02-03 President And Fellows Of Harvard College Programming of cells for tolerogenic therapies
JP5696150B2 (ja) * 2009-09-10 2015-04-08 エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ 高い強度を有するシームレスなアルギン酸塩カプセル
WO2011109834A2 (en) 2010-03-05 2011-09-09 President And Fellows Of Harvard College Enhancement of skeletal muscle stem cell engrafment by dual delivery of vegf and igf-1
US9226524B2 (en) 2010-03-26 2016-01-05 Philip Morris Usa Inc. Biopolymer foams as filters for smoking articles
WO2011163669A2 (en) 2010-06-25 2011-12-29 President And Fellows Of Harvard College Co-delivery of stimulatory and inhibitory factors to create temporally stable and spatially restricted zones
WO2012048165A2 (en) 2010-10-06 2012-04-12 President And Fellows Of Harvard College Injectable, pore-forming hydrogels for materials-based cell therapies
US8946194B2 (en) 2010-10-08 2015-02-03 Board Of Regents, University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
EP2624874A4 (en) 2010-10-08 2014-04-02 Univ Texas ADHESIVE MEMBRANE WITH ALGINATE AND HYALURONIC ACID FOR BIOMEDICAL APPLICATIONS
US9603894B2 (en) 2010-11-08 2017-03-28 President And Fellows Of Harvard College Materials presenting notch signaling molecules to control cell behavior
WO2012140650A2 (en) 2011-04-12 2012-10-18 Hepacore Ltd. Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
EP2701753B1 (en) 2011-04-27 2018-12-26 President and Fellows of Harvard College Cell-friendly inverse opal hydrogels for cell encapsulation, drug and protein delivery, and functional nanoparticle encapsulation
EP2701745B1 (en) 2011-04-28 2018-07-11 President and Fellows of Harvard College Injectable preformed macroscopic 3-dimensional scaffolds for minimally invasive administration
US9675561B2 (en) 2011-04-28 2017-06-13 President And Fellows Of Harvard College Injectable cryogel vaccine devices and methods of use thereof
EP2714073B1 (en) 2011-06-03 2021-03-10 President and Fellows of Harvard College In situ antigen-generating cancer vaccine
US9765205B2 (en) 2011-08-24 2017-09-19 Algix, Llc Macrophyte-based bioplastic
WO2013031030A1 (en) 2011-09-01 2013-03-07 L'oreal Cosmetic sheet
CA2870309C (en) 2012-04-16 2024-02-20 President And Fellows Of Harvard College Mesoporous silica compositions for modulating immune responses
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
WO2014102802A1 (en) 2012-12-30 2014-07-03 Hadasit Medical Research Services And Development Ltd. Alginate compositions and uses thereof
WO2014169250A1 (en) * 2013-04-11 2014-10-16 President And Fellows Of Harvard College Prefabricated alginate-drug bandages
EP3003266A2 (en) * 2013-05-29 2016-04-13 Therakine Biodelivery GmbH Hydrophilic microparticles, drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
KR102181336B1 (ko) 2013-06-13 2020-11-24 오르제네시스 엘티디. 세포 집단, 이의 전환분화 방법 및 이용 방법
US10682400B2 (en) 2014-04-30 2020-06-16 President And Fellows Of Harvard College Combination vaccine devices and methods of killing cancer cells
CN104001213B (zh) * 2014-05-07 2016-06-29 广州贝奥吉因生物科技有限公司 一种软骨组织工程用多孔支架及其制备方法
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
MA41296A (fr) 2014-12-30 2017-11-07 Orgenesis Ltd Procédés de transdifférenciation et procédés d'utilisation de ceux-ci
WO2016123573A1 (en) 2015-01-30 2016-08-04 President And Fellows Of Harvard College Peritumoral and intratumoral materials for cancer therapy
US11150242B2 (en) 2015-04-10 2021-10-19 President And Fellows Of Harvard College Immune cell trapping devices and methods for making and using the same
FR3039555B1 (fr) 2015-07-30 2017-08-18 Univ Toulouse Iii - Paul Sabatier Procede de preparation de matrices poreuses polymeres biocompatibles et biodegradables trimensionnelles et applications
CN105169473B (zh) * 2015-10-19 2018-06-29 东南大学 一种超细孔隙水凝胶支架及其制备方法
JP7033066B2 (ja) 2016-01-07 2022-03-09 ビー．ジー．ネゲブ テクノロジーズ アンド アプリケーションズ リミテッド， アット ベン‐グリオン ユニバーシティー 免疫寛容応答を生成する組成物及び方法
CN115531609A (zh) 2016-02-06 2022-12-30 哈佛学院校长同事会 重塑造血巢以重建免疫
CN115305229A (zh) 2016-07-13 2022-11-08 哈佛学院院长等 抗原呈递细胞模拟支架及其制备和使用方法
US10821200B2 (en) 2016-12-05 2020-11-03 Hyalo Technologies, LLC Method of sterilization of microparticles
SG11201911256UA (en) 2017-05-08 2020-01-30 Orgenesis Ltd Transdifferentiated cell populations and methods of use thereof
CN108853570B (zh) * 2018-07-16 2021-04-27 浦易（上海）生物技术有限公司 一种止血海绵及其制备方法
US11661576B2 (en) 2019-02-05 2023-05-30 Corning Incorporated Packed-bed bioreactor systems and methods of using the same
US11118151B2 (en) 2019-11-05 2021-09-14 Corning Incorporated Fixed bed bioreactor and methods of using the same
KR102396513B1 (ko) * 2019-12-30 2022-05-10 조선대학교 산학협력단 버섯의 감마-아미노부티르산 함량 증가용 조성물
CA3165835A1 (en) * 2020-01-13 2021-07-22 The Regents Of The University Of California Devices and methods for high-stability supercooling of aqueous media and biological matter
EP4122980A4 (en) * 2020-03-17 2024-03-27 Japan Tobacco Inc METHOD FOR PRODUCING POROUS BODY AND POROUS BODY
WO2021217560A1 (en) 2020-04-30 2021-11-04 L'oreal Kit for caring for the skin

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3653383A (en) * 1969-07-30 1972-04-04 Freeze Dry Products Algin sponge and process therefor
FR2167329A1 (en) * 1972-01-13 1973-08-24 Freeze Dry Products Water-absorbent porous algin sponges - readily disposable for medical uses
JPS5571537A (en) * 1978-11-24 1980-05-29 Shin Etsu Chem Co Ltd Method of manufacturing sponge-like molded body
US4412947A (en) * 1979-09-12 1983-11-01 Seton Company Collagen sponge
JPS5658469A (en) * 1979-10-19 1981-05-21 Yoshinari Masuyama Molding method of glucomannan flour
DE2943520C2 (de) * 1979-10-27 1982-05-19 Fa. Carl Freudenberg, 6940 Weinheim Verfahren zur Herstellung von Kollagenschwamm für medizinische oder kosmetische Zwecke
US4522753A (en) * 1980-07-17 1985-06-11 Massachusetts Institute Of Technology Method for preserving porosity in porous materials
US4578067A (en) * 1982-04-12 1986-03-25 Alcon (Puerto Rico) Inc. Hemostatic-adhesive, collagen dressing for severed biological surfaces
GB2148901A (en) * 1983-10-04 1985-06-05 Johnson & Johnson Protein/polysaccharide complexes
US4515637A (en) * 1983-11-16 1985-05-07 Seton Company Collagen-thrombin compositions
US5510254A (en) * 1986-04-18 1996-04-23 Advanced Tissue Sciences, Inc. Three dimensional cell and tissue culture system
US5219361A (en) * 1988-09-16 1993-06-15 Clemson University Soft tissue implant with micron-scale surface texture to optimize anchorage
US5602026A (en) * 1988-10-14 1997-02-11 The General Hospital Corporation Culturing liver cells between two supports
JP4215273B2 (ja) * 1991-04-25 2009-01-28 ブラウン ユニヴァーシティ リサーチ ファンデーション 選択された治療物質放出用の移植可能で生体適合性の免疫遮断性ビークル
JPH05125214A (ja) * 1991-11-01 1993-05-21 Komatsu Ltd 超高分子量ポリエチレンポーラス体およびその製造方法
GB9206509D0 (en) * 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
GB9210574D0 (en) * 1992-05-18 1992-07-01 Ca Nat Research Council Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications
US5690996A (en) * 1992-11-02 1997-11-25 Sepragen Cross-linked cellulose sponge
US5660857A (en) * 1993-03-22 1997-08-26 Johnson & Johnson Medical Inc. Biopolymer composites
GB2281861B (en) * 1993-09-21 1997-08-20 Johnson & Johnson Medical Bioabsorbable wound implant materials containing microspheres
US6176874B1 (en) * 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
DE9315877U1 (de) 1993-10-18 1994-01-05 Greenland Gmbh & Co Kg Heuwerbungsmaschine
CA2115592C (en) * 1994-02-14 1998-09-22 Kumiko Kimura Production of glucomannan sponge
US5834029A (en) * 1994-07-20 1998-11-10 Cytotherapeutics, Inc. Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment
US5891558A (en) * 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
EP0830381A4 (en) * 1995-06-09 2000-11-22 William N Drohan CHITINE HYDROGELS, PRODUCTION METHOD AND USE
US5965125A (en) * 1995-10-25 1999-10-12 Transkaryotic Therapies, Inc. Hybrid matrix implants and explants
EP0907721A1 (en) * 1996-05-28 1999-04-14 Brown University Research Foundation Hyaluronan based biodegradable scaffolds for tissue repair
GB2318577B (en) * 1996-10-28 2000-02-02 Johnson & Johnson Medical Solvent dried polysaccharide sponges
FI111011B (fi) * 1997-01-15 2003-05-15 Orion Yhtymae Oyj Mikro-organismien kiinteä kasvualusta, sen valmistus ja käyttö
GB9704749D0 (en) * 1997-03-07 1997-04-23 Univ London Tissue Implant
CA2285329A1 (en) * 1997-03-31 1998-10-08 The Regents Of The University Of Michigan Open pore biodegradable matrices and process for making them
US6471993B1 (en) * 1997-08-01 2002-10-29 Massachusetts Institute Of Technology Three-dimensional polymer matrices

Also Published As

Publication number Publication date
DE69724780T2 (de) 2004-07-15
EP0901384A1 (en) 1999-03-17
ES2206707T3 (es) 2004-05-16
IL118376A0 (en) 1996-09-12
WO1997044070A1 (en) 1997-11-27
AU714647B2 (en) 2000-01-06
CA2256327A1 (en) 1997-11-27
AU2711797A (en) 1997-12-09
ATE249251T1 (de) 2003-09-15
US6425918B1 (en) 2002-07-30
EP0901384B1 (en) 2003-09-10
US20030078672A1 (en) 2003-04-24
US6334968B1 (en) 2002-01-01
JP2000512666A (ja) 2000-09-26
DK0901384T3 (da) 2004-01-19
DE69724780D1 (de) 2003-10-16
CA2256327C (en) 2012-07-24
US6793675B2 (en) 2004-09-21

Similar Documents

Publication Publication Date Title
PT901384E (pt) Esponjas de polissacarido para cultura e transplante de celulas
DE69635398D1 (de) Thermoformiertes Behälter für Zellcultureinsatz
DE59502120D1 (de) Gerät zur bildung von seifenschaum und dessen verwendung
DE69524970T2 (de) Mehrschichtiger gasdurchlässiger behälter zur zuchtung von adhärenten und nicht-adhärenten zellen
ATE262358T1 (de) Zusammensetzung zur gewebsregeneration
UY34152A (es) ?oxazolidinonas substituidas y su uso?.
MA24303A1 (fr) Lignes cellulaires immortalisees pour la croissance du virus.
DE69913505D1 (de) Polymerschaummaterialien mit hoher saugfähigkeit
BR9801144A (pt) Uso de copolímeros em bloco tendo ligados blocos de siloxano na produção de espumas de poliuretano
AU4926899A (en) Hematopoietic cell composition for use in transplantation
YU19499A (sh) Benzonaftiridini kao bronhijalni terapeutici
ITRM920036A0 (it) Elettrolita polimerico composito particolarmente utile per l'impiego in accumulatori elettochimici leggeri.
ATE353637T1 (de) Element zur applikation einer salbe und ein salbenpflaster, das dieses verwendet
ATE223963T1 (de) Toilettenreinigungsblock
ES2090214T3 (es) Cuerpos moldeados de espumas con distintos intervalos de densidad y procedimiento y util de moldeo para su obtencion.
SE9700158L (sv) Absorberande struktur med förbätrade absorptionsegenskaper
MY117327A (en) Water-disintegratable cleaning sheet containing alkylcellulose.
ATE289349T1 (de) Vorläufer von normalen neuralen epithelzellen
DE3850712D1 (de) Schaumhemmender Zusatz für saure Flüssigkeiten.
FR2657879B1 (fr) Plaque de culture cellulaire.
AR007739A1 (es) Un proceso para la preparacion de n-(r)-(2-hidroxi-2-piridina-3-il-etil) -2-(4-nitro-fenil)-acetamida
FR2706483B1 (fr) Bioréacteur, destiné notamment à la culture de cellules.
DE9314776U1 (de) Styroporplattenschneidegerät für den Handwerker
KR970054728U (ko) 정화조용 미생물 배양상
IL126861A0 (en) Polysaccharide sponges for cell culture and transplantation