PT90039A - Processo de preparacao de oxidos de 1,2,4-benzotriazina e de composicoes faemaceuticas que os contem - Google Patents

Processo de preparacao de oxidos de 1,2,4-benzotriazina e de composicoes faemaceuticas que os contem

Info

Publication number
PT90039A
PT90039A PT90039A PT9003989A PT90039A PT 90039 A PT90039 A PT 90039A PT 90039 A PT90039 A PT 90039A PT 9003989 A PT9003989 A PT 9003989A PT 90039 A PT90039 A PT 90039A
Authority
PT
Portugal
Prior art keywords
faemaceutical
compositions
contain
preparation procedure
benzotriazine oxides
Prior art date
Application number
PT90039A
Other languages
English (en)
Other versions
PT90039B (pt
Inventor
William W Lee
J Martin Brown
Edward W Grange
Abelardo P Martinez
Michael Tracy
Original Assignee
Stanford Res Inst Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stanford Res Inst Int filed Critical Stanford Res Inst Int
Publication of PT90039A publication Critical patent/PT90039A/pt
Publication of PT90039B publication Critical patent/PT90039B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
    • C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
PT90039A 1988-03-18 1989-03-17 Processo de preparacao de oxidos de 1,2,4-benzotriazina e de composicoes faemaceuticas que os contem PT90039B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16987388A 1988-03-18 1988-03-18

Publications (2)

Publication Number Publication Date
PT90039A true PT90039A (pt) 1989-11-10
PT90039B PT90039B (pt) 1994-05-31

Family

ID=22617563

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90039A PT90039B (pt) 1988-03-18 1989-03-17 Processo de preparacao de oxidos de 1,2,4-benzotriazina e de composicoes faemaceuticas que os contem

Country Status (14)

Country Link
EP (1) EP0413706B1 (pt)
JP (1) JP2793312B2 (pt)
KR (1) KR0140894B1 (pt)
AT (1) ATE170515T1 (pt)
AU (1) AU637572B2 (pt)
CA (1) CA1339217C (pt)
DE (1) DE68928802T2 (pt)
DK (1) DK175885B1 (pt)
ES (1) ES2013123A6 (pt)
IE (1) IE62911B1 (pt)
NO (1) NO179005C (pt)
NZ (1) NZ228323A (pt)
PT (1) PT90039B (pt)
WO (1) WO1989008647A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0478545B1 (en) * 1989-09-18 1999-08-11 Sri International 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents
US5110347A (en) * 1990-11-26 1992-05-05 E. I Du Pont De Nemours And Company Substituted fused heterocyclic herbicides
WO2005082867A1 (en) * 2004-03-01 2005-09-09 Auckland Uniservices Limited Novel 1,2,4-benzotriazine-1,4-dioxides

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2489352A (en) * 1946-04-10 1949-11-29 Merck & Co Inc Halogen compounds of 3 aminobenzotriazine 1, 2, 4 oxide-1
US2489359A (en) * 1947-01-10 1949-11-29 Merck & Co Inc Benzotriazines
CH487171A (de) * 1963-10-22 1970-03-15 Siegfried Ag Verfahren zur Herstellung therapeutisch wirksamer 1,2-Dihydro-1,2,4-benztriazine
DE1809390A1 (de) * 1968-11-16 1970-06-11 Bayer Ag Phosphor-,Phosphon- bzw.Thionophosphor-(-phosphon)-saeureester und Verfahren zu ihrer Herstellung
DE2255825C3 (de) * 1972-11-15 1978-03-30 Bayer Ag, 5090 Leverkusen Mikrobizide Mittel auf der Basis von S-N-Aminobenzo-l^-Triazin-di-N-oxiden (1,4)
IE38778B1 (en) * 1973-02-02 1978-05-24 Ciba Geigy New 1,2,4-benzotriazine derivatives
SE7501624L (pt) * 1974-03-15 1975-09-16 Ciba Geigy Ag
DE2538179C2 (de) * 1975-08-27 1986-05-28 Bayer Ag, 5090 Leverkusen 3-Alkoxy-benzo-1,2,4-triazine, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Fungizide
US4091098A (en) * 1977-04-25 1978-05-23 Merck & Co., Inc. 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
DE2740887A1 (de) * 1977-09-10 1979-03-22 Bayer Ag Mittel zur bekaempfung von pflanzenbakteriosen
DE3790581T1 (pt) * 1986-09-25 1988-08-25

Also Published As

Publication number Publication date
DK223090D0 (da) 1990-09-17
EP0413706A1 (en) 1991-02-27
WO1989008647A1 (en) 1989-09-21
NO179005B (no) 1996-04-09
NO904003L (no) 1990-09-13
AU637572B2 (en) 1993-06-03
JPH03505867A (ja) 1991-12-19
NO904003D0 (no) 1990-09-13
IE62911B1 (en) 1995-03-08
DE68928802T2 (de) 1999-04-01
PT90039B (pt) 1994-05-31
IE890721L (en) 1989-09-18
ES2013123A6 (es) 1990-04-16
DK223090A (da) 1990-11-15
ATE170515T1 (de) 1998-09-15
CA1339217C (en) 1997-08-05
AU3433789A (en) 1989-10-05
NZ228323A (en) 1992-09-25
EP0413706B1 (en) 1998-09-02
JP2793312B2 (ja) 1998-09-03
NO179005C (no) 1996-07-17
DE68928802D1 (de) 1998-10-08
KR0140894B1 (ko) 1998-06-01
KR900700466A (ko) 1990-08-13
DK175885B1 (da) 2005-05-23

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19931119

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20090317