PT89371A - Processo de preparacao de 1-aralquil-1,2-di-hidropirimidina-2-tionas e de composicoes farmaceuticas que as contem - Google Patents

Processo de preparacao de 1-aralquil-1,2-di-hidropirimidina-2-tionas e de composicoes farmaceuticas que as contem

Info

Publication number
PT89371A
PT89371A PT89371A PT8937188A PT89371A PT 89371 A PT89371 A PT 89371A PT 89371 A PT89371 A PT 89371A PT 8937188 A PT8937188 A PT 8937188A PT 89371 A PT89371 A PT 89371A
Authority
PT
Portugal
Prior art keywords
aralquil
hydropyrimidine
tions
dihydro
pharmaceutical compositions
Prior art date
Application number
PT89371A
Other languages
English (en)
Inventor
Lawrence Ivan Kruse
Stephen Torey Ross
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of PT89371A publication Critical patent/PT89371A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/38—One sulfur atom
    • C07D239/40—One sulfur atom as doubly bound sulfur atom or as unsubstituted mercapto radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT89371A 1987-12-31 1988-12-30 Processo de preparacao de 1-aralquil-1,2-di-hidropirimidina-2-tionas e de composicoes farmaceuticas que as contem PT89371A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14005287A 1987-12-31 1987-12-31

Publications (1)

Publication Number Publication Date
PT89371A true PT89371A (pt) 1989-12-29

Family

ID=22489527

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89371A PT89371A (pt) 1987-12-31 1988-12-30 Processo de preparacao de 1-aralquil-1,2-di-hidropirimidina-2-tionas e de composicoes farmaceuticas que as contem

Country Status (6)

Country Link
EP (1) EP0323147A3 (pt)
JP (1) JPH03501730A (pt)
AU (1) AU3031889A (pt)
PT (1) PT89371A (pt)
WO (1) WO1989006131A1 (pt)
ZA (1) ZA889670B (pt)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR977401A (fr) * 1948-02-18 1951-04-02 Goodrich Co B F Perfectionnements relatifs aux 2-mercapto-3-arylpyrimidines et à leur procédé de préparation
NO120426B (pt) * 1965-10-21 1970-10-19 Geigy Ag J R
US3701831A (en) * 1969-11-19 1972-10-31 Merck & Co Inc Method of inhibiting dopamine beta-hydroxylase
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors

Also Published As

Publication number Publication date
JPH03501730A (ja) 1991-04-18
EP0323147A2 (en) 1989-07-05
ZA889670B (en) 1989-12-27
WO1989006131A1 (en) 1989-07-13
AU3031889A (en) 1989-08-01
EP0323147A3 (en) 1990-08-08

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Legal Events

Date Code Title Description
FC3A Refusal

Effective date: 19940721