ZA889670B - 1-aralkyl-1,2-dihydropyrimidine-2-thiones - Google Patents

1-aralkyl-1,2-dihydropyrimidine-2-thiones

Info

Publication number
ZA889670B
ZA889670B ZA889670A ZA889670A ZA889670B ZA 889670 B ZA889670 B ZA 889670B ZA 889670 A ZA889670 A ZA 889670A ZA 889670 A ZA889670 A ZA 889670A ZA 889670 B ZA889670 B ZA 889670B
Authority
ZA
South Africa
Prior art keywords
thiones
dihydropyrimidine
aralkyl
Prior art date
Application number
ZA889670A
Other languages
English (en)
Inventor
Lawrence Ivan Kruse
Ivan Kruse Lawrence
Stephen Torey Ross
Torey Ross Stephen
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of ZA889670B publication Critical patent/ZA889670B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/38—One sulfur atom
    • C07D239/40—One sulfur atom as doubly bound sulfur atom or as unsubstituted mercapto radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA889670A 1987-12-31 1988-12-28 1-aralkyl-1,2-dihydropyrimidine-2-thiones ZA889670B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14005287A 1987-12-31 1987-12-31

Publications (1)

Publication Number Publication Date
ZA889670B true ZA889670B (en) 1989-12-27

Family

ID=22489527

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA889670A ZA889670B (en) 1987-12-31 1988-12-28 1-aralkyl-1,2-dihydropyrimidine-2-thiones

Country Status (6)

Country Link
EP (1) EP0323147A3 (xx)
JP (1) JPH03501730A (xx)
AU (1) AU3031889A (xx)
PT (1) PT89371A (xx)
WO (1) WO1989006131A1 (xx)
ZA (1) ZA889670B (xx)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR977401A (fr) * 1948-02-18 1951-04-02 Goodrich Co B F Perfectionnements relatifs aux 2-mercapto-3-arylpyrimidines et à leur procédé de préparation
NL6614808A (xx) * 1965-10-21 1967-04-24
US3701831A (en) * 1969-11-19 1972-10-31 Merck & Co Inc Method of inhibiting dopamine beta-hydroxylase
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors

Also Published As

Publication number Publication date
AU3031889A (en) 1989-08-01
EP0323147A3 (en) 1990-08-08
PT89371A (pt) 1989-12-29
EP0323147A2 (en) 1989-07-05
WO1989006131A1 (en) 1989-07-13
JPH03501730A (ja) 1991-04-18

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