PT88580B - Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4 - Google Patents

Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4 Download PDF

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Publication number
PT88580B
PT88580B PT88580A PT8858088A PT88580B PT 88580 B PT88580 B PT 88580B PT 88580 A PT88580 A PT 88580A PT 8858088 A PT8858088 A PT 8858088A PT 88580 B PT88580 B PT 88580B
Authority
PT
Portugal
Prior art keywords
hydroxy
isomers
propylphenoxy
process according
prepared
Prior art date
Application number
PT88580A
Other languages
English (en)
Portuguese (pt)
Other versions
PT88580A (pt
Inventor
Richard Mathias Weier
Michael Allan Stealey
James Ronald Deason
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/100,685 external-priority patent/US4808729A/en
Application filed by Searle & Co filed Critical Searle & Co
Publication of PT88580A publication Critical patent/PT88580A/pt
Publication of PT88580B publication Critical patent/PT88580B/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/06Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT88580A 1987-09-24 1988-09-23 Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4 PT88580B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/100,685 US4808729A (en) 1987-09-24 1987-09-24 Leukotriene LTD4 and LTB4 antagonists
US07/241,265 US4923891A (en) 1987-09-24 1988-09-09 Leukotriene LTD4 and LTB4 antagonists

Publications (2)

Publication Number Publication Date
PT88580A PT88580A (pt) 1988-10-01
PT88580B true PT88580B (pt) 1992-11-30

Family

ID=26797440

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88580A PT88580B (pt) 1987-09-24 1988-09-23 Processo para a preparacao de derivados de 1,3-ditio(oxatio ou dioxo)lano uteis como antagonistas de leucotrieno ltd4 e ltb4

Country Status (14)

Country Link
US (1) US4923891A (OSRAM)
EP (1) EP0308956B1 (OSRAM)
JP (1) JPH01132577A (OSRAM)
KR (1) KR890005082A (OSRAM)
AU (1) AU610246B2 (OSRAM)
DE (1) DE3878806T2 (OSRAM)
DK (1) DK530888A (OSRAM)
ES (1) ES2045052T3 (OSRAM)
FI (1) FI884377L (OSRAM)
GR (1) GR3007858T3 (OSRAM)
IL (1) IL87800A (OSRAM)
NO (1) NO171412C (OSRAM)
NZ (1) NZ226318A (OSRAM)
PT (1) PT88580B (OSRAM)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5579409A (en) * 1991-09-27 1996-11-26 E. I. Du Pont De Nemours And Company Methods for determining the exterior points of an object in a background
JPH11507669A (ja) 1995-06-12 1999-07-06 ジー.ディー.サール アンド カンパニー シクロオキシゲナーゼ−2インヒビターとロイコトリエンb▲下4▼受容体アンタゴニストの組合せによる炎症と炎症関連疾患の治療
ES2243978T3 (es) * 1996-02-13 2005-12-01 G.D. SEARLE & CO. Composiciones que comprenden un inhibidor de la ciclooxigenasa-2 y un antagonista del receptor de leucotrieno b4.
EP1090916B1 (en) * 1999-10-06 2003-09-03 Dainippon Ink And Chemicals, Inc. 4-methylene-1,3-dioxolanes having functional groups
US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
RU2472790C2 (ru) 2005-11-22 2013-01-20 Сегетис Инк. Кетали глицериллевулината и их применение
WO2009048874A1 (en) * 2007-10-09 2009-04-16 Segetis, Inc. Method of making ketals and acetals
WO2010036884A1 (en) 2008-09-25 2010-04-01 Segetis, Inc. Ketal ester derivatives
BRPI1013943B1 (pt) 2009-06-22 2020-03-17 Segetis, Inc. Composto, método para sintetizar o mesmo, composição e composição lubrificante
JP5846696B2 (ja) 2010-05-10 2016-01-20 サジティス・インコーポレイテッド アルキルケタールエステルを含有する個別健康管理用処方物および製造方法
CN103025720B (zh) 2010-08-03 2016-06-01 赛格提斯公司 用于制备缩醛和缩酮的方法以及由此制备的缩醛和缩酮
BR112013003424A2 (pt) 2010-08-12 2016-08-02 Segetis Inc composições de remoção carboxiéster cetal, métodos de fabricação, e usos dos mesmos
EP2603565B1 (en) 2010-08-12 2015-10-07 Segetis, Inc. Latex coating compositions including carboxy ester ketal coalescents, methods of manufacture, and uses thereof
EP2613760A2 (en) 2010-09-07 2013-07-17 Segetis, Inc. Compositions for dyeing keratin fibers
US8188030B2 (en) 2010-09-13 2012-05-29 Segetis, Inc. Fabric softener compositions and methods of manufacture thereof
US8728625B2 (en) 2010-10-18 2014-05-20 Segetis, Inc. Water reducible coating compositions including carboxy ester ketals, methods of manufacture, and uses thereof
WO2014047428A1 (en) 2012-09-21 2014-03-27 Segetis, Inc. Cleaning, surfactant, and personal care compositions
EP2925738B1 (en) 2012-11-29 2018-01-10 GFBiochemicals Limited Carboxy ester ketals, methods of manufacture, and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2839445A (en) * 1954-01-11 1958-06-17 Du Pont Fungicidal and anti-oxidant compositions comprising 1, 3-dithiolanes
FR1448340A (fr) * 1964-07-09 1966-08-05 Boehringer Sohn Ingelheim Procédé pour fabriquer des nouveaux 1, 3-dioxolanes
FR1445013A (fr) * 1964-07-09 1966-07-08 Thomae Gmbh Dr K Procédé pour fabriquer des nouveaux acides dioxolano-2-carboxyliques
FR4493M (OSRAM) * 1964-07-09 1966-10-10
GB1427918A (en) * 1972-05-26 1976-03-10 Shell Int Research Herbicidal glycerol acetals
FR2577552B1 (fr) * 1985-02-20 1987-09-04 Sori Soc Rech Ind Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique

Also Published As

Publication number Publication date
FI884377A7 (fi) 1989-03-25
US4923891A (en) 1990-05-08
NO884223D0 (no) 1988-09-23
FI884377A0 (fi) 1988-09-23
DK530888A (da) 1989-03-25
ES2045052T3 (es) 1994-01-16
FI884377L (fi) 1989-03-25
EP0308956A3 (en) 1990-06-13
GR3007858T3 (OSRAM) 1993-08-31
DE3878806T2 (de) 1993-07-01
NZ226318A (en) 1991-08-27
EP0308956A2 (en) 1989-03-29
EP0308956B1 (en) 1993-03-03
NO171412B (no) 1992-11-30
AU610246B2 (en) 1991-05-16
IL87800A (en) 1992-12-01
IL87800A0 (en) 1989-03-31
DK530888D0 (da) 1988-09-23
PT88580A (pt) 1988-10-01
JPH01132577A (ja) 1989-05-25
NO884223L (no) 1989-03-28
KR890005082A (ko) 1989-05-11
NO171412C (no) 1993-03-10
DE3878806D1 (de) 1993-04-08
AU2274188A (en) 1989-04-06

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FG3A Patent granted, date of granting

Effective date: 19920521

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19941130