PT884052E - Materiais indutores de cartilagem/caso para reparacao - Google Patents

Materiais indutores de cartilagem/caso para reparacao

Info

Publication number
PT884052E
PT884052E PT96938460T PT96938460T PT884052E PT 884052 E PT884052 E PT 884052E PT 96938460 T PT96938460 T PT 96938460T PT 96938460 T PT96938460 T PT 96938460T PT 884052 E PT884052 E PT 884052E
Authority
PT
Portugal
Prior art keywords
bone morphogenetic
polyoxyethylene
bone
cartilage
glycol
Prior art date
Application number
PT96938460T
Other languages
English (en)
Inventor
Takesada Shimura
Satsuki Toriyama
Original Assignee
Bioph Biotech Entw Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioph Biotech Entw Pharm Gmbh filed Critical Bioph Biotech Entw Pharm Gmbh
Publication of PT884052E publication Critical patent/PT884052E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30756—Cartilage endoprostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Organic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
PT96938460T 1995-11-17 1996-11-14 Materiais indutores de cartilagem/caso para reparacao PT884052E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7322402A JPH09143093A (ja) 1995-11-17 1995-11-17 軟骨・骨誘導性修復用材料

Publications (1)

Publication Number Publication Date
PT884052E true PT884052E (pt) 2004-04-30

Family

ID=18143268

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96938460T PT884052E (pt) 1995-11-17 1996-11-14 Materiais indutores de cartilagem/caso para reparacao

Country Status (19)

Country Link
US (2) US6903071B2 (pt)
EP (1) EP0884052B1 (pt)
JP (1) JPH09143093A (pt)
KR (1) KR100458413B1 (pt)
CN (1) CN1165340C (pt)
AT (1) ATE254470T1 (pt)
AU (1) AU712445C (pt)
CA (1) CA2235400C (pt)
DE (1) DE69630811T2 (pt)
DK (1) DK0884052T3 (pt)
ES (1) ES2211993T3 (pt)
HK (1) HK1018205A1 (pt)
HU (1) HU226201B1 (pt)
NO (1) NO325119B1 (pt)
NZ (1) NZ322188A (pt)
PT (1) PT884052E (pt)
RU (1) RU2180234C2 (pt)
UA (1) UA63896C2 (pt)
WO (1) WO1997018829A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09143093A (ja) * 1995-11-17 1997-06-03 Hoechst Japan Ltd 軟骨・骨誘導性修復用材料
EP0957943B2 (en) * 1997-02-07 2008-11-26 Stryker Corporation Matrix-free osteogenic devices, implants and methods of use thereof
US6309659B1 (en) 1997-09-02 2001-10-30 Gensci Orthobiologics, Inc. Reverse phase connective tissue repair composition
US9616150B2 (en) 1999-10-29 2017-04-11 Children's Hospital Los Angeles Bone hemostasis method and materials
EP1231869B1 (en) * 1999-10-29 2005-09-21 Children's Hospital of Los Angeles Bone hemostasis method and materials
DK1229940T3 (da) 1999-11-15 2014-08-18 Piramal Healthcare Canada Ltd Temperaturstyret og ph-afhængig selvgelerende, vandig biopolymeropløsning
US7747332B2 (en) * 2000-05-08 2010-06-29 International Rehabilitative Sciences, Inc. Electrical stimulation combined with a biologic to increase osteogenesis
CA2412505C (en) * 2000-06-29 2009-02-03 Caroline D. Hoemann Composition and method for the repair and regeneration of cartilage and other tissues
JP2002306163A (ja) * 2001-04-11 2002-10-22 Chemo Sero Therapeut Res Inst 大腸菌を宿主とする遺伝子組換えヒトトロンビンの調製方法
US7205337B2 (en) * 2001-12-21 2007-04-17 Isotis Orthobiologics, Inc. End-capped polymers and compositions containing such compounds
DE60209795T2 (de) * 2001-12-21 2006-10-05 IsoTis Orthobiologics, Inc., Irvine Zusammensetzungen enthaltend endgruppen-verkappte polyalkylenglykole
CN1325056C (zh) * 2002-05-20 2007-07-11 大塚制药株式会社 用于改善黑斑病的组合物以及用于减轻肌肤黯淡的组合物
AU2002337479A1 (en) * 2002-09-04 2004-03-29 Hadasit Medical Research Services & Development Ltd. Compositions comprising bone marrow cells, demineralized bone matrix and rtg polymers for use in the induction of bone and cartilage formation
WO2004071451A2 (en) 2003-02-12 2004-08-26 Ceremed, Inc. Random alkylene oxide copolymers for medical and surgical utilities
EP2001528A4 (en) * 2006-03-23 2012-04-04 Citagenix Inc REVERSE-PHASE OSSEOCONDUCTIVE COMPOSITION
US20100047299A1 (en) * 2007-01-25 2010-02-25 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Use of gdf-5 for the improvement or maintenance of dermal appearance
US8290780B2 (en) 2009-06-24 2012-10-16 International Business Machines Corporation Dynamically extending the speech prompts of a multimodal application
KR101405104B1 (ko) * 2011-12-26 2014-06-10 한남대학교 산학협력단 약물의 서방형 방출 특성을 가지는 골 시멘트
US10743996B2 (en) * 2017-03-24 2020-08-18 Robert L. Bundy Amnion putty for cartilage repair
CN109125791B (zh) * 2018-09-29 2019-08-30 广州贝奥吉因生物科技有限公司 一种具有促进骨修复功能的可吸收骨蜡及制备方法

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JPS61277612A (ja) * 1985-05-31 1986-12-08 Kiyoshi Morikawa 接種用徐放性組成物
JPH0723322B2 (ja) 1985-12-07 1995-03-15 克之 藤井 液状骨形成剤からなる注射液
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
US4863732A (en) * 1987-12-16 1989-09-05 Collagen Corporation Injectable composition for inductive bone repair
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
JPH045227A (ja) * 1990-04-17 1992-01-09 Pharmetrix Corp 歯周疾患治療システム
CA2040460C (en) * 1990-05-01 1997-06-10 Tacey X. Viegas Drug delivery with thermoreversible gels
AU662155B2 (en) * 1991-05-10 1995-08-24 Celtrix Pharmaceuticals, Inc. Targeted delivery of bone growth factors
WO1993000050A1 (en) * 1991-06-21 1993-01-07 Genetics Institute, Inc. Pharmaceutical formulations of osteogenic proteins
EP0551626A1 (en) * 1991-12-19 1993-07-21 LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. Thermoreversible gel as a liquid pharmaceutical carrier for a galenic formulation
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IL110589A0 (en) * 1993-08-10 1994-11-11 Bioph Biotech Entw Pharm Gmbh Growth/differentiation factor of the TGF- beta family
JP3696265B2 (ja) * 1994-02-04 2005-09-14 日本オルガノン株式会社 点鼻液剤
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JPH09143093A (ja) * 1995-11-17 1997-06-03 Hoechst Japan Ltd 軟骨・骨誘導性修復用材料

Also Published As

Publication number Publication date
EP0884052A1 (en) 1998-12-16
NZ322188A (en) 2000-10-27
CN1207047A (zh) 1999-02-03
KR19990067676A (ko) 1999-08-25
NO982236L (no) 1998-06-26
NO325119B1 (no) 2008-02-04
NO982236D0 (no) 1998-05-15
DK0884052T3 (da) 2004-03-29
US6903071B2 (en) 2005-06-07
ATE254470T1 (de) 2003-12-15
AU712445B2 (en) 1999-11-04
DE69630811D1 (de) 2003-12-24
CA2235400C (en) 2007-12-18
HK1018205A1 (en) 1999-12-17
WO1997018829A1 (fr) 1997-05-29
CA2235400A1 (en) 1997-05-29
US20020168381A1 (en) 2002-11-14
DE69630811T2 (de) 2004-06-17
JPH09143093A (ja) 1997-06-03
AU712445C (en) 2002-03-28
HUP0000411A3 (en) 2005-11-28
EP0884052B1 (en) 2003-11-19
US20050013864A1 (en) 2005-01-20
UA63896C2 (en) 2004-02-16
KR100458413B1 (ko) 2005-04-06
ES2211993T3 (es) 2004-07-16
HUP0000411A2 (hu) 2001-04-28
AU7586996A (en) 1997-06-11
RU2180234C2 (ru) 2002-03-10
EP0884052A4 (en) 1999-05-06
CN1165340C (zh) 2004-09-08
US7238657B2 (en) 2007-07-03
HU226201B1 (en) 2008-06-30

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