PT86625A - Process for the preparation of dipyrazoles useful as bronchodilators - Google Patents

Process for the preparation of dipyrazoles useful as bronchodilators

Info

Publication number
PT86625A
PT86625A PT86625A PT8662588A PT86625A PT 86625 A PT86625 A PT 86625A PT 86625 A PT86625 A PT 86625A PT 8662588 A PT8662588 A PT 8662588A PT 86625 A PT86625 A PT 86625A
Authority
PT
Portugal
Prior art keywords
dipyrazoles
bronchodilators
useful
preparation
compounds
Prior art date
Application number
PT86625A
Other languages
English (en)
Other versions
PT86625B (pt
Inventor
Michael E Le Tourneau
Norton P Peet
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of PT86625A publication Critical patent/PT86625A/pt
Publication of PT86625B publication Critical patent/PT86625B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Paper (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT86625A 1987-01-27 1988-01-26 Processo para a preparacao de compostos dipirazolicos utilizaveis como agentes broncodilatadores PT86625B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/007,305 US4734430A (en) 1987-01-27 1987-01-27 Dipyrazoles and their use as bronchodilators

Publications (2)

Publication Number Publication Date
PT86625A true PT86625A (pt) 1988-02-01
PT86625B PT86625B (pt) 1991-12-31

Family

ID=21725393

Family Applications (1)

Application Number Title Priority Date Filing Date
PT86625A PT86625B (pt) 1987-01-27 1988-01-26 Processo para a preparacao de compostos dipirazolicos utilizaveis como agentes broncodilatadores

Country Status (19)

Country Link
US (1) US4734430A (pt)
EP (1) EP0276833B1 (pt)
JP (1) JP2571411B2 (pt)
KR (2) KR880009024A (pt)
CN (1) CN88100343A (pt)
AT (1) ATE118494T1 (pt)
AU (1) AU600789B2 (pt)
CA (1) CA1324607C (pt)
DE (1) DE3853012T2 (pt)
DK (1) DK35188A (pt)
ES (1) ES2070829T3 (pt)
FI (1) FI89357C (pt)
HU (1) HU197906B (pt)
IL (1) IL85188A (pt)
NO (1) NO167288C (pt)
NZ (1) NZ223259A (pt)
PH (1) PH23496A (pt)
PT (1) PT86625B (pt)
ZA (1) ZA88526B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734429A (en) * 1987-01-27 1988-03-29 Merrell Dow Pharmaceuticals Inc. Cycloalkane[1,2-c:4,3-c']dipyrazoles and their use as bronchodilators
DE4232544A1 (de) * 1992-09-29 1994-03-31 Thomae Gmbh Dr K Arzneimittel enthaltend 1,5,6,7-Tetrahydro-4H-indazol-4-one, neue 1,5,6,7-Tetrahydro-4H-indazol-4-one und Verfahren zu ihrer Herstellung
GB9911053D0 (en) * 1999-05-12 1999-07-14 Pharmacia & Upjohn Spa 4,5,6,7-tetrahydroindazole derivatives process for their preparation and their use as antitumour agents
AU2003218989A1 (en) * 2002-02-19 2003-09-09 Pharmacia Italia S.P.A. Tricyclic pyrazole derivatives, process for their preparation and their use as antitumor agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3404157A (en) * 1965-02-24 1968-10-01 American Cyanamid Co Substituted pyrroloindazole compounds
US3787430A (en) * 1972-07-13 1974-01-22 Squibb & Sons Inc Derivatives of dipyrazolo(3,4-b;3',4'-d)pyridines
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
US4135048A (en) * 1977-05-17 1979-01-16 Laboratorios Cosmos S.A. Anaphylactic inhibiting trans-octahydronaphto[1,2-c:5,6-c'] dipyrazoles

Also Published As

Publication number Publication date
NO167288C (no) 1991-10-23
DE3853012T2 (de) 1995-07-20
NO167288B (no) 1991-07-15
NO880339D0 (no) 1988-01-26
EP0276833A3 (en) 1990-01-24
JPS63192775A (ja) 1988-08-10
PT86625B (pt) 1991-12-31
EP0276833A2 (en) 1988-08-03
US4734430A (en) 1988-03-29
EP0276833B1 (en) 1995-02-15
AU1073088A (en) 1988-07-28
ZA88526B (en) 1988-09-28
FI89357C (fi) 1993-09-27
DE3853012D1 (de) 1995-03-23
FI89357B (fi) 1993-06-15
DK35188D0 (da) 1988-01-26
HU197906B (en) 1989-06-28
FI880283A0 (fi) 1988-01-22
FI880283A (fi) 1988-07-28
CN88100343A (zh) 1988-08-31
ATE118494T1 (de) 1995-03-15
KR880009024A (ko) 1988-09-13
CA1324607C (en) 1993-11-23
KR960001476B1 (ko) 1996-01-31
IL85188A (en) 1992-02-16
ES2070829T3 (es) 1995-06-16
NZ223259A (en) 1990-03-27
HUT47281A (en) 1989-02-28
AU600789B2 (en) 1990-08-23
PH23496A (en) 1989-08-16
NO880339L (no) 1988-07-28
JP2571411B2 (ja) 1997-01-16
DK35188A (da) 1988-07-28
IL85188A0 (en) 1988-07-31

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Effective date: 19941231