GB1416669A - Acetonaphthones - Google Patents

Acetonaphthones

Info

Publication number
GB1416669A
GB1416669A GB3540874A GB3540874A GB1416669A GB 1416669 A GB1416669 A GB 1416669A GB 3540874 A GB3540874 A GB 3540874A GB 3540874 A GB3540874 A GB 3540874A GB 1416669 A GB1416669 A GB 1416669A
Authority
GB
United Kingdom
Prior art keywords
tetrahydro
aug
acetonaphthones
warnerlambert
naphthopyran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3540874A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00392152A external-priority patent/US3843730A/en
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of GB1416669A publication Critical patent/GB1416669A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

1416669 Acetonaphthones WARNERLAMBERT CO 12 Aug 1974 [27 Aug 1973] 35408/74 Heading C2C The invention comprises compounds of the formula wherein the Z ring is of the following structure They may be obtained by reacting dimethyl sulphoxide with Na 2 H 2 in an inert solvent, adding thereto a 5,6,7,8-tetrahydro-1 or 3- hydroxy-2-naphthoate ester, maintaining the reaction mixture at a temperature of up to 50‹ C., and thereafter precipitating the Na salt of the product by adding a non-polar solvent. They are useful in the preparation of tetrahydro-hydroxymethyl-naphthopyran-4-ones.
GB3540874A 1973-08-27 1974-08-12 Acetonaphthones Expired GB1416669A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00392152A US3843730A (en) 1971-08-25 1973-08-27 Ortho-hydroxy-omega-(methylsulfinyl-)acetonaphthones and process for producing same

Publications (1)

Publication Number Publication Date
GB1416669A true GB1416669A (en) 1975-12-03

Family

ID=23549462

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3540874A Expired GB1416669A (en) 1973-08-27 1974-08-12 Acetonaphthones

Country Status (5)

Country Link
JP (1) JPS5245708B2 (en)
CA (1) CA1037061A (en)
DK (1) DK410974A (en)
FR (1) FR2242378B1 (en)
GB (1) GB1416669A (en)

Also Published As

Publication number Publication date
JPS5245708B2 (en) 1977-11-17
JPS50105645A (en) 1975-08-20
CA1037061A (en) 1978-08-22
FR2242378A1 (en) 1975-03-28
DK410974A (en) 1975-04-28
FR2242378B1 (en) 1976-12-31
AU7208074A (en) 1976-02-12
DE2436943A1 (en) 1975-03-27
DE2436943B2 (en) 1976-01-15

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee