PT85551A - Process for the preparation of antiviral pyrimidine derivatives and of pharmaceutical compositions containing the same - Google Patents

Process for the preparation of antiviral pyrimidine derivatives and of pharmaceutical compositions containing the same

Info

Publication number
PT85551A
PT85551A PT85551A PT8555187A PT85551A PT 85551 A PT85551 A PT 85551A PT 85551 A PT85551 A PT 85551A PT 8555187 A PT8555187 A PT 8555187A PT 85551 A PT85551 A PT 85551A
Authority
PT
Portugal
Prior art keywords
preparation
same
pharmaceutical compositions
compositions containing
pyrimidine derivatives
Prior art date
Application number
PT85551A
Other languages
English (en)
Other versions
PT85551B (pt
Inventor
Robert Wilson Lambert
Joseph Armstrong Martin
Gareth John Thomas
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868620070A external-priority patent/GB8620070D0/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT85551A publication Critical patent/PT85551A/pt
Publication of PT85551B publication Critical patent/PT85551B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT85551A 1986-08-18 1987-08-18 Processo para a preparacao de derivados da pirimidina com actividade antiviral e de composicoes farmaceuticas que os contem PT85551B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868620070A GB8620070D0 (en) 1986-08-18 1986-08-18 Pyrimidine derivatives
GB878711336A GB8711336D0 (en) 1986-08-18 1987-05-14 Pyrimidine derivatives

Publications (2)

Publication Number Publication Date
PT85551A true PT85551A (en) 1987-09-01
PT85551B PT85551B (pt) 1990-05-31

Family

ID=26291195

Family Applications (1)

Application Number Title Priority Date Filing Date
PT85551A PT85551B (pt) 1986-08-18 1987-08-18 Processo para a preparacao de derivados da pirimidina com actividade antiviral e de composicoes farmaceuticas que os contem

Country Status (22)

Country Link
US (2) US4851519A (pt)
EP (1) EP0257378B1 (pt)
JP (1) JPH0794453B2 (pt)
CN (1) CN1020106C (pt)
AU (1) AU602909B2 (pt)
CA (1) CA1303031C (pt)
CS (1) CS272225B2 (pt)
DE (1) DE3771146D1 (pt)
DK (1) DK375787A (pt)
ES (1) ES2040715T3 (pt)
FI (1) FI86639C (pt)
GR (1) GR3002636T3 (pt)
HU (1) HU199500B (pt)
IE (1) IE61061B1 (pt)
IL (1) IL83509A (pt)
MC (1) MC1846A1 (pt)
MX (1) MX174238B (pt)
NO (1) NO170884C (pt)
NZ (1) NZ221412A (pt)
PH (1) PH24653A (pt)
PT (1) PT85551B (pt)
ZW (1) ZW14187A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK163128C (da) * 1986-08-12 1992-06-15 Hoffmann La Roche Pyrimidinnucleosider, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende pyrimidinnucleosiderne og anvendelse af pyrimidinnucleosiderne
NO170884C (no) * 1986-08-18 1992-12-23 Hoffmann La Roche Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyrimidinderivater
US5312961A (en) * 1989-02-14 1994-05-17 Elf Sanofi 2-amino-7-hydroxytetralin carboxylalkyl ethers
CA2076849A1 (en) * 1990-02-28 1991-08-29 Kouki Kitagawa Physiologically active substance well capable of permeating biomembrane
US5652335A (en) * 1990-02-28 1997-07-29 Teikoku Seiyaku Kabushiki Kaisha Physiologically active substance well capable of permeating biomembrane
US5306722A (en) * 1992-09-02 1994-04-26 Bristol-Myers Squibb Company Thymidine derivatives and therapeutic method of use
US6040298A (en) * 1992-12-23 2000-03-21 Oclassen Pharmaceuticals, Inc. Methods for treatment with compositions effective against acyclovir-resistant strains of herpes viruses
GB9606264D0 (en) * 1995-07-13 1996-05-29 Hoffmann La Roche Pyrimidine nucleoside derivatives
GB9514268D0 (en) * 1995-07-13 1995-09-13 Hoffmann La Roche Pyrimidine nucleoside
GB9608199D0 (en) * 1995-08-04 1996-06-26 Hoffmann La Roche Pyrimide nucleoside derivatives
US5783689A (en) * 1996-11-12 1998-07-21 University Of Notre Dame Antibacterial and antifungal nucleosides
WO2006025920A2 (en) * 2004-06-19 2006-03-09 Human Biomolecular Research Institute Modulators of central nervous system neurotransmitters
JP5205873B2 (ja) * 2006-09-12 2013-06-05 和光純薬工業株式会社 新規なジデオキシヌクレオシド誘導体
US7629447B2 (en) * 2006-09-12 2009-12-08 Wako Pure Chemical Industries, Ltd. Dideoxynucleoside derivatives
JP5785168B2 (ja) * 2009-07-31 2015-09-24 エスリス ゲーエムベーハーｅｔｈｒｉｓ ＧｍｂＨ タンパク質発現用未修飾および修飾ヌクレオチドの組み合わせを有するｒｎａ
DE102013225403A1 (de) 2013-12-10 2015-06-11 BSH Hausgeräte GmbH Haushaltsgerät mit einer in einem Verstauraum versenkbaren Tür mit vertikaler Lageveränderungsmöglichkeit einer Drehachse einer Lagereinheit sowie Verfahren zum öffnen und Schließen einer Tür
DE102013225402A1 (de) 2013-12-10 2015-06-11 BSH Hausgeräte GmbH Haushaltsgerät mit einer in einem Stauraum versenkbaren Tür und verschiebbarer Drehachse einer Lagereinheit sowie Verfahren zum öffnen und Schließen einer derartigen Tür
DE102013225401A1 (de) 2013-12-10 2015-06-11 BSH Hausgeräte GmbH Haushaltsgerät mit einer in einen Verstauraum einfahrbaren Tür und Verfahren zum öffnen und Schließen einer Tür eines Haushaltsgeräts
DE102015206576A1 (de) 2015-04-13 2016-10-13 BSH Hausgeräte GmbH Haushaltsgerät mit einer in einem Verstauraum versenkbaren Tür mit spezifischer Lagereinheit
DE102015206577A1 (de) 2015-04-13 2016-10-13 BSH Hausgeräte GmbH Haushaltsgerät mit einer in einem Verstauraum versenkbaren Tür mit elliptischer Kulisse zur Bewegung eines Lagerbügels einer Tür-Lagereinheit
ES2879826T3 (es) 2015-06-15 2021-11-23 Nmd Pharma As Compuestos para su uso en el tratamiento de trastornos neuromusculares
US11147788B2 (en) 2017-12-14 2021-10-19 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US10385028B2 (en) 2017-12-14 2019-08-20 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US11730714B2 (en) 2017-12-14 2023-08-22 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
DE102018201949A1 (de) 2018-02-08 2019-08-08 BSH Hausgeräte GmbH Gargerät mit einer in einen Verstauraum versenkbaren Tür mit einem spezifischen Koppelmodul, sowie Verfahren zum Bewegen einer Tür
DE102018201950A1 (de) 2018-02-08 2019-08-08 BSH Hausgeräte GmbH Gargerät mit einem Technikteil für eine versenkbare Tür, welches eine Führungsbahn in einer oberen Höhenhälfte des Technikteils aufweist

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4128639A (en) * 1977-12-14 1978-12-05 Research Corporation Nitrosourea analogs of thymidine
US4211773A (en) * 1978-10-02 1980-07-08 Sloan Kettering Institute For Cancer Research 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides
DE3045375A1 (de) * 1980-12-02 1982-07-01 Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen Neue substituierte pyrimidin-nukleoside mit antiviraler wirkung, verfahren zu deren herstellung und daraus zubereitete arzneiformen
DE3045342A1 (de) * 1980-12-02 1982-07-01 Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen Neue substituierte pyrimidin-nukleoside mit antiviraler und cytostatischer wirkung, verfahren zu deren herstellung und daraus bereitete arzneiformen
US4762823A (en) * 1985-10-16 1988-08-09 Sloan-Kettering Institute For Cancer Research Nucleosides of 5-monofluoromethyluracil and 5-difluoromethyluracil
DK363987A (da) * 1986-08-08 1988-02-09 Hoffmann La Roche Pyrimidinderivater
DK163128C (da) * 1986-08-12 1992-06-15 Hoffmann La Roche Pyrimidinnucleosider, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende pyrimidinnucleosiderne og anvendelse af pyrimidinnucleosiderne
NO170884C (no) * 1986-08-18 1992-12-23 Hoffmann La Roche Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyrimidinderivater

Also Published As

Publication number Publication date
HU199500B (en) 1990-02-28
PH24653A (en) 1990-09-07
DK375787A (da) 1988-02-19
NO170884C (no) 1992-12-23
HUT45544A (en) 1988-07-28
FI873555A (fi) 1988-02-19
CA1303031C (en) 1992-06-09
GR3002636T3 (en) 1993-01-25
EP0257378B1 (de) 1991-07-03
NO872961L (no) 1988-02-19
AU7684187A (en) 1988-02-25
IL83509A0 (en) 1988-01-31
MX7769A (es) 1993-11-01
NZ221412A (en) 1990-11-27
DK375787D0 (da) 1987-07-17
AU602909B2 (en) 1990-11-01
MC1846A1 (fr) 1988-09-30
FI873555A0 (fi) 1987-08-17
JPS6351384A (ja) 1988-03-04
ES2040715T3 (es) 1993-11-01
CN1020106C (zh) 1993-03-17
FI86639B (fi) 1992-06-15
IL83509A (en) 1994-05-30
CS583487A2 (en) 1990-03-14
CS272225B2 (en) 1991-01-15
FI86639C (fi) 1992-09-25
NO872961D0 (no) 1987-07-15
EP0257378A1 (de) 1988-03-02
JPH0794453B2 (ja) 1995-10-11
DE3771146D1 (de) 1991-08-08
MX174238B (es) 1994-05-02
CN87105758A (zh) 1988-03-02
ZW14187A1 (en) 1988-02-24
US5010060A (en) 1991-04-23
IE872191L (en) 1988-02-18
IE61061B1 (en) 1994-09-21
PT85551B (pt) 1990-05-31
NO170884B (no) 1992-09-14
US4851519A (en) 1989-07-25

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Legal Events

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MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000531