PT84654B - Processo para a preparacao de derivados de 4-h-1benzopirano-4-ona e de composicoes farmaceuticas que os contenham - Google Patents

Processo para a preparacao de derivados de 4-h-1benzopirano-4-ona e de composicoes farmaceuticas que os contenham

Info

Publication number
PT84654B
PT84654B PT84654A PT8465487A PT84654B PT 84654 B PT84654 B PT 84654B PT 84654 A PT84654 A PT 84654A PT 8465487 A PT8465487 A PT 8465487A PT 84654 B PT84654 B PT 84654B
Authority
PT
Portugal
Prior art keywords
alkyl
aryl
cycloalkyl
represents hydrogen
integer
Prior art date
Application number
PT84654A
Other languages
English (en)
Other versions
PT84654A (de
Inventor
Alinussein Nomanbta Dohadwalla
Noel John De Souza
Aftab Dawoodbhai Lakdawala
Ramchandra Ganapati Naik
Richard Helmut Rupp
Samba Laxminarayan Kattige
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PT84654A publication Critical patent/PT84654A/pt
Publication of PT84654B publication Critical patent/PT84654B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
PT84654A 1986-04-11 1987-04-10 Processo para a preparacao de derivados de 4-h-1benzopirano-4-ona e de composicoes farmaceuticas que os contenham PT84654B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863612337 DE3612337A1 (de) 1986-04-11 1986-04-11 4h-1-benzopyran-4-on-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
PT84654A PT84654A (de) 1987-05-01
PT84654B true PT84654B (pt) 1989-12-29

Family

ID=6298535

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84654A PT84654B (pt) 1986-04-11 1987-04-10 Processo para a preparacao de derivados de 4-h-1benzopirano-4-ona e de composicoes farmaceuticas que os contenham

Country Status (16)

Country Link
US (1) US4900727A (pt)
EP (1) EP0241003B1 (pt)
JP (1) JPH0686446B2 (pt)
KR (1) KR950009861B1 (pt)
AT (2) ATE95519T1 (pt)
AU (1) AU602891B2 (pt)
CA (1) CA1332238C (pt)
DE (2) DE3612337A1 (pt)
DK (1) DK169760B1 (pt)
ES (1) ES2060582T3 (pt)
HK (1) HK1006021A1 (pt)
IE (1) IE62244B1 (pt)
IL (1) IL82149A (pt)
IN (1) IN164232B (pt)
PT (1) PT84654B (pt)
ZA (1) ZA872555B (pt)

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KR100423899B1 (ko) 2000-05-10 2004-03-24 주식회사 엘지생명과학 세포 증식 억제제로 유용한 1,1-디옥소이소티아졸리딘을갖는 인다졸
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US7271193B2 (en) * 2002-07-08 2007-09-18 Nicholas Piramal India, Ltd. Inhibitors of cyclin-dependent kinases and their use
US7884127B2 (en) * 2002-07-08 2011-02-08 Pirimal Life Sciences Ltd. Inhibitors of cyclin dependent kinases and their use
US7915301B2 (en) * 2002-07-08 2011-03-29 Piramal Life Science Limited Inhibitors of cyclin dependent kinases and their use
ATE423110T1 (de) * 2002-07-17 2009-03-15 Cytokinetics Inc Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen
EP1554265A4 (en) * 2002-09-13 2008-05-07 Cytokinetics Inc COMPOSITIONS, COMPOSITIONS AND M THODES
US20050165089A1 (en) * 2003-10-06 2005-07-28 Gustave Bergnes Compounds, compositions and methods
DE602004024115D1 (de) * 2003-12-09 2009-12-24 Us Gov Health & Human Serv Verfahren zur unterdrückung einer immunantwort oder zur behandlung von proliferativen erkrankungen
US20050171182A1 (en) * 2003-12-11 2005-08-04 Roger Briesewitz Methods and compositions for use in the treatment of mutant receptor tyrosine kinase driven cellular proliferative diseases
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US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
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CN108289861B (zh) 2015-08-03 2021-11-02 大日本住友制药肿瘤公司 用于治疗癌症的组合疗法
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JP7196160B2 (ja) 2017-09-12 2022-12-26 スミトモ ファーマ オンコロジー， インコーポレイテッド Ｍｃｌ－１阻害剤アルボシジブを用いた、ｂｃｌ－２阻害剤に対して非感受性である癌の治療レジメン
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Also Published As

Publication number Publication date
EP0241003B1 (de) 1993-10-06
ES2060582T3 (es) 1994-12-01
CA1332238C (en) 1994-10-04
IL82149A (en) 1994-01-25
IL82149A0 (en) 1987-10-30
IE62244B1 (en) 1995-01-11
KR950009861B1 (en) 1995-08-29
AU7139787A (en) 1987-10-15
HK1006021A1 (en) 1999-02-05
IN164232B (pt) 1989-02-04
JPS62242680A (ja) 1987-10-23
DK185287A (da) 1987-10-12
EP0241003A2 (de) 1987-10-14
EP0241003A3 (en) 1988-10-12
ZA872555B (en) 1987-11-25
DE3787661D1 (de) 1993-11-11
DK185287D0 (da) 1987-04-10
AU602891B2 (en) 1990-11-01
AT389875B (de) 1990-02-12
KR870010045A (ko) 1987-11-30
ATA260587A (de) 1989-07-15
DE3612337A1 (de) 1987-10-15
ATE95519T1 (de) 1993-10-15
IE870941L (en) 1987-10-11
US4900727A (en) 1990-02-13
DK169760B1 (da) 1995-02-20
JPH0686446B2 (ja) 1994-11-02
PT84654A (de) 1987-05-01

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