PT83873B - Processo de preparacao de medicamentos contendo hexadecilfosfocolina - Google Patents

Processo de preparacao de medicamentos contendo hexadecilfosfocolina

Info

Publication number
PT83873B
PT83873B PT83873A PT8387386A PT83873B PT 83873 B PT83873 B PT 83873B PT 83873 A PT83873 A PT 83873A PT 8387386 A PT8387386 A PT 8387386A PT 83873 B PT83873 B PT 83873B
Authority
PT
Portugal
Prior art keywords
pct
hexadecillospholin
preparation
medicines containing
sec
Prior art date
Application number
PT83873A
Other languages
English (en)
Portuguese (pt)
Other versions
PT83873A (de
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Publication of PT83873A publication Critical patent/PT83873A/pt
Publication of PT83873B publication Critical patent/PT83873B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Electrically Operated Instructional Devices (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
PT83873A 1985-12-04 1986-12-04 Processo de preparacao de medicamentos contendo hexadecilfosfocolina PT83873B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3542893 1985-12-04
DE3606631 1986-02-28

Publications (2)

Publication Number Publication Date
PT83873A PT83873A (de) 1987-01-01
PT83873B true PT83873B (pt) 1989-01-17

Family

ID=25838509

Family Applications (2)

Application Number Title Priority Date Filing Date
PT83873A PT83873B (pt) 1985-12-04 1986-12-04 Processo de preparacao de medicamentos contendo hexadecilfosfocolina
PT83872A PT83872B (pt) 1985-12-04 1986-12-04 Processo de preparacao de compostos de fosforo e de medicamentos contendo-os

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT83872A PT83872B (pt) 1985-12-04 1986-12-04 Processo de preparacao de compostos de fosforo e de medicamentos contendo-os

Country Status (15)

Country Link
US (2) US4837023A (en:Method)
EP (4) EP0225608A3 (en:Method)
JP (2) JPH0637393B2 (en:Method)
AT (2) ATE64529T1 (en:Method)
CA (2) CA1280369C (en:Method)
DE (4) DE3641379A1 (en:Method)
DK (2) DK172954B1 (en:Method)
ES (2) ES2032755T3 (en:Method)
FI (2) FI873363A0 (en:Method)
GR (2) GR3002487T3 (en:Method)
HU (2) HU203201B (en:Method)
IE (2) IE59778B1 (en:Method)
NO (2) NO175620C (en:Method)
PT (2) PT83873B (en:Method)
WO (2) WO1987003480A2 (en:Method)

Families Citing this family (43)

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US5916884A (en) * 1985-12-04 1999-06-29 Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften Compositions containing a mixture of phosphorus compounds and alkylglycerols
CA2001401A1 (en) * 1988-10-25 1990-04-25 Claude Piantadosi Quaternary amine containing ether or ester lipid derivatives and therapeutic compositions
US5182271A (en) * 1989-08-10 1993-01-26 Sandoz Ltd. Thioether, keto-ester and alkyl phospholipids useful in treating multiple sclerosis
EP0412941B1 (en) * 1989-08-10 1996-05-15 Sandoz Ltd. Phospholipids for the treatment of multiple sclerosis
US5290769A (en) * 1989-09-27 1994-03-01 Asta Pharma Aktiengesellschaft Use of hexadecylphosphocholine for the treatment of psoriasis
EP0916343A1 (de) * 1989-09-27 1999-05-19 ASTA Medica Aktiengesellschaft Verwendung von Alkylphosphorsäure-Verbindungen zur Bekämpfung von Psoriasis-Erkrankungen
DE4111105A1 (de) * 1991-04-05 1992-10-08 Max Planck Gesellschaft Neue erucyl-, brassidyl- und nervonylderivate
US5369097A (en) * 1991-04-25 1994-11-29 The University Of British Columbia Phosphonates as anti-cancer agents
US5506217A (en) * 1991-04-25 1996-04-09 The University Of British Columbia Phosphonates as anti-cancer agents
ATE158295T1 (de) * 1991-07-04 1997-10-15 Asta Medica Ag Verfahren zur herstellung von alkylphosphocholinen und reinherstellung derselben
US6254879B1 (en) 1991-09-27 2001-07-03 Max-Planck-Gessellschaft zun Förderung der Wissenschaften e.V. Methods of treating protozoal diseases
DE4132344A1 (de) * 1991-09-27 1993-04-01 Max Planck Gesellschaft Verfahren zur herstellung eines arzneimittels zur oralen oder topischen verabreichung bei der behandlung von leishmaniasis
US5298655A (en) * 1991-09-27 1994-03-29 Merck & Co., Inc. Farnesyl pyrophosphate analogs
DE4222910A1 (de) * 1992-07-11 1994-01-13 Asta Medica Ag Neue Phospholipidderivate
US6172050B1 (en) 1992-07-11 2001-01-09 Asta Medica Aktiengesellschaft Phospholipid derivatives
DE4235911A1 (de) * 1992-10-23 1994-04-28 Asta Medica Ag Stabilisierte Hexadecylphosphocholinlösungen in Glycerinalkylethern
CA2164717C (en) * 1993-06-10 2009-10-20 Louis S. Kucera Method of combatting hepatitis b virus infection
US6551623B1 (en) 1993-09-09 2003-04-22 Lorus Therapeutics Inc. Immunomodulating compositions from bile
CA2171281C (en) 1993-09-09 1998-12-29 Romeo Rang Immunomodulating compositions from bile
US7135584B2 (en) * 1995-08-07 2006-11-14 Wake Forest University Lipid analogs for treating viral infections
EP1852121A3 (en) * 1994-08-29 2007-11-21 Wake Forest University Lipid analogs for treating viral infections
US5574025A (en) * 1994-10-26 1996-11-12 Merck & Co., Inc. Inhibitors of prenyl-protein transferases
AU1573495A (en) * 1995-02-10 1996-08-27 University Of British Columbia, The {4-hexadecyl-3-methoxy-butyl} phosphonic acid and its protienconjugates useful as anti-cancer agents
KR19980703088A (ko) 1995-03-16 1998-09-05 라카일레 지, 필리페 신규의 침전탄산칼슘 안료를 포함하는 잉크젯 기록지
KR100499190B1 (ko) * 1996-03-29 2006-04-17 교와 핫꼬 고교 가부시끼가이샤 육모제
US20040101569A1 (en) * 1996-05-16 2004-05-27 Lorus Therapeutics Inc. Immunomodulating compositions from bile
US6121245A (en) * 1997-01-29 2000-09-19 Firshein; Richard N. Method of treating cancer using alkylglycerols in conjunction with chemotherapy
SE9701912D0 (sv) * 1997-05-22 1997-05-22 Interhealth Ab Pharmaceutical composition and use thereof
US7582678B2 (en) * 1997-07-09 2009-09-01 D-Pharm Limited Use of branched-chain fatty acids and derivatives thereof for the treatment of pain
JP2002501015A (ja) * 1998-01-22 2002-01-15 アスタ メディカ アクチエンゲゼルシャフト リーシュマニア症の治療における経口投与のためのミルテフォシンを含有する固形医薬品
US7026469B2 (en) * 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells
IL137672A0 (en) 2000-08-03 2001-10-31 Dpharm Ltd Derivatives of branched-chain lipophilic molecules and uses thereof
US7309696B2 (en) 2000-10-19 2007-12-18 Wake Forest University Compositions and methods for targeting cancer cells
US6960738B2 (en) * 2001-05-29 2005-11-01 Koninklijke Philips Electronics N.V. Metal-ceramic bond
EP1423976A1 (en) * 2001-08-31 2004-06-02 Thomson Licensing S.A. Sequence counter for an audio visual stream
AU2002346284A1 (en) * 2002-04-26 2003-11-10 Rudolf Perl Pharmaceutical compositions of phospholipid derivatives
US20050187191A1 (en) * 2004-02-20 2005-08-25 Kucera Louis S. Methods and compositions for the treatment of respiratory syncytial virus
AR058397A1 (es) 2005-12-19 2008-01-30 Zentaris Gmbh Derivados de alquilfosfolipidos con citotoxicidad reducida y usos de los mismos
EP2120873B1 (en) * 2006-12-20 2012-06-27 Alphaptose Gmbh Topical dosage form comprising tri-substituted glycerol compounds
JP2011057647A (ja) * 2009-09-14 2011-03-24 Adeka Corp 化粧料
JP6441073B2 (ja) 2011-06-24 2018-12-19 ジーアールアイ バイオ, インコーポレイテッドGRI Bio, Inc. 炎症状態の予防および処置
CN102491994B (zh) * 2011-12-07 2014-10-15 宁波九胜创新医药科技有限公司 一种胆碱磷酸烷基酯的制备方法
KR102665487B1 (ko) * 2014-12-09 2024-05-10 쥐알아이 바이오,아이엔씨. 염증 질환의 예방 및 치료

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3225227A1 (de) * 1982-07-06 1984-01-12 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Derivate des n.n-bis-(2-chlor-aethyl)-phosphorsaeureamids
JPS5984824A (ja) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd 抗腫瘍剤
US4690935A (en) * 1983-03-31 1987-09-01 Wayne State University Inhibition of tumor growth and metastasis with calcium channel blocker compounds
JPS60184092A (ja) 1984-03-01 1985-09-19 Kao Corp リン酸エステルおよびその製法

Also Published As

Publication number Publication date
ES2038215T3 (es) 1993-07-16
DK172954B1 (da) 1999-10-18
WO1987003480A3 (en) 1988-02-25
EP0230575A3 (de) 1987-12-02
JPH0637393B2 (ja) 1994-05-18
GR3005168T3 (en:Method) 1993-05-24
EP0248062B1 (de) 1992-05-06
FI873363A7 (fi) 1987-08-03
ATE75608T1 (de) 1992-05-15
DK393187A (da) 1987-07-28
JP2857084B2 (ja) 1999-02-10
IE863176L (en) 1987-06-04
DE3679908D1 (de) 1991-07-25
WO1987003478A2 (en) 1987-06-18
ATE64529T1 (de) 1991-07-15
EP0225608A2 (de) 1987-06-16
EP0230575A2 (de) 1987-08-05
NO873243L (no) 1987-10-02
HUT44441A (en) 1988-03-28
FI873363L (fi) 1987-08-03
DE3641491A1 (de) 1987-09-17
DK398587D0 (da) 1987-07-30
NO174877B (no) 1994-04-18
JPH0859677A (ja) 1996-03-05
JPS63501719A (ja) 1988-07-14
FI873364A0 (fi) 1987-08-03
NO175620C (no) 1994-11-09
CA1338627C (en) 1996-10-01
EP0225608A3 (de) 1987-10-28
NO174877C (no) 1994-07-27
EP0248047B1 (de) 1991-06-19
FI873364A7 (fi) 1987-08-03
CA1280369C (en) 1991-02-19
DK398587A (da) 1987-07-30
PT83872A (de) 1987-01-01
WO1987003480A2 (en) 1987-06-18
HUT44431A (en) 1988-03-28
WO1987003478A3 (en) 1987-09-24
IE59777B1 (en) 1994-04-06
DE19375061I2 (de) 2008-11-20
PT83873A (de) 1987-01-01
DE3641379A1 (de) 1987-09-03
FI873363A0 (fi) 1987-08-03
HU208143B (en) 1993-08-30
DK393187D0 (da) 1987-07-28
NO873243D0 (no) 1987-08-03
EP0248047A1 (de) 1987-12-09
EP0248062A1 (de) 1987-12-09
HU203201B (en) 1991-06-28
US4837023A (en) 1989-06-06
US5049552A (en) 1991-09-17
IE59778B1 (en) 1994-04-06
NO873244D0 (no) 1987-08-03
IE863177L (en) 1987-06-04
NO175620B (en:Method) 1994-08-01
ES2032755T3 (es) 1993-03-01
NO873244L (no) 1987-10-01
PT83872B (pt) 1989-01-17
GR3002487T3 (en) 1992-12-30

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