PT83044B - Processo para a preparacao de 3-imidazolilmetil-tetra-hidro-carbazolonas - Google Patents
Processo para a preparacao de 3-imidazolilmetil-tetra-hidro-carbazolonasInfo
- Publication number
- PT83044B PT83044B PT83044A PT8304486A PT83044B PT 83044 B PT83044 B PT 83044B PT 83044 A PT83044 A PT 83044A PT 8304486 A PT8304486 A PT 8304486A PT 83044 B PT83044 B PT 83044B
- Authority
- PT
- Portugal
- Prior art keywords
- sub
- sup
- hydrogen atom
- alkyl
- cycloalkyl
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 102000040125 5-hydroxytryptamine receptor family Human genes 0.000 abstract 1
- 108091032151 5-hydroxytryptamine receptor family Proteins 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858518742A GB8518742D0 (en) | 1985-07-24 | 1985-07-24 | Process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT83044A PT83044A (en) | 1986-08-01 |
| PT83044B true PT83044B (pt) | 1989-02-28 |
Family
ID=10582814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT83044A PT83044B (pt) | 1985-07-24 | 1986-07-23 | Processo para a preparacao de 3-imidazolilmetil-tetra-hidro-carbazolonas |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4957609A (pt) |
| EP (1) | EP0221629B1 (pt) |
| JP (1) | JPS6277381A (pt) |
| KR (1) | KR920001671B1 (pt) |
| AT (1) | ATE73452T1 (pt) |
| CA (1) | CA1281721C (pt) |
| DE (1) | DE3684235D1 (pt) |
| ES (1) | ES2000936A6 (pt) |
| FI (1) | FI84351C (pt) |
| GB (1) | GB8518742D0 (pt) |
| GR (1) | GR861927B (pt) |
| PT (1) | PT83044B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8617994D0 (en) * | 1986-07-23 | 1986-08-28 | Glaxo Group Ltd | Heterocyclic compounds |
| EP0317088A1 (en) * | 1987-10-22 | 1989-05-24 | Glaxo Group Limited | Ketone derivatives |
| US5225431A (en) * | 1987-10-23 | 1993-07-06 | Burroughs Wellcome Co. | Therapeutic substituted indole compounds and compositions thereof |
| ATE84532T1 (de) * | 1988-04-13 | 1993-01-15 | Ici America Inc | Cyclische amide. |
| DE4010797A1 (de) * | 1990-04-04 | 1991-10-10 | Hoechst Ag | Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
| ES2043535B1 (es) * | 1992-03-13 | 1994-08-01 | Vita Invest Sa | Procedimiento para la obtencion de la 1,2,3,9-tetrahidro-9-metil-3-(2-metil-1h-imidazol-1-il)metil*-4h-carbazol-4-ona. |
| HU212934B (en) | 1992-10-14 | 1996-12-30 | Richter Gedeon Vegyeszet | Process for producing novel alkoxalylated carbazolone derivatives |
| CA2106642C (en) * | 1992-10-14 | 2005-08-16 | Peter Bod | Carbazolone derivatives and process for preparing the same |
| JP2004525083A (ja) * | 2000-10-30 | 2004-08-19 | テバ ファーマシューティカル インダストリーズ リミティド | 塩酸オンダンセトロンの新規結晶及び溶媒和物形態並びにその製法 |
| US20020115707A1 (en) * | 2001-01-11 | 2002-08-22 | Rami Lidor-Hadas | Process for preparing pure ondansetron hydrochloride dihydrate |
| CN1665823A (zh) * | 2002-04-29 | 2005-09-07 | 特瓦药厂有限公司 | 制备1,2,3,9－四氢－9－甲基－3－[(2－甲基－1h－咪唑－1－基)甲基]－4h－咔唑－4－酮的方法 |
| US20050131045A1 (en) * | 2002-04-30 | 2005-06-16 | Judith Aronhime | Novel crystal forms of ondansetron, processes for their preparation, pharmaceutical, compositions containing the novel forms and methods for treating nausea using them |
| FI6164U1 (fi) * | 2003-01-09 | 2004-03-15 | Synthon Bv | Ondansetronmuotoja |
| US7390503B1 (en) | 2003-08-22 | 2008-06-24 | Barr Laboratories, Inc. | Ondansetron orally disintegrating tablets |
| JP5254029B2 (ja) * | 2005-11-16 | 2013-08-07 | エフ．ホフマン−ラ ロシュ アーゲー | Ｔｈｏｃの新規製造方法 |
| EP2470503B1 (en) * | 2009-08-24 | 2014-03-12 | Keki Hormusji Gharda | Method for synthesis of n-alkyl carbazole and derivatives thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO164025C (no) * | 1984-01-25 | 1990-08-22 | Glaxo Group Ltd | Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-imidazolylmetyl-tetrahydrokarbazolon-derivater. |
| GR871809B (en) * | 1986-11-28 | 1988-03-07 | Glaxo Group Ltd | Process for the preparation of tricyclic ketones |
-
1985
- 1985-07-24 GB GB858518742A patent/GB8518742D0/en active Pending
-
1986
- 1986-07-23 CA CA000514469A patent/CA1281721C/en not_active Expired - Lifetime
- 1986-07-23 DE DE8686305672T patent/DE3684235D1/de not_active Expired - Fee Related
- 1986-07-23 EP EP86305672A patent/EP0221629B1/en not_active Expired - Lifetime
- 1986-07-23 FI FI863020A patent/FI84351C/fi not_active IP Right Cessation
- 1986-07-23 GR GR861927A patent/GR861927B/el unknown
- 1986-07-23 AT AT86305672T patent/ATE73452T1/de not_active IP Right Cessation
- 1986-07-23 PT PT83044A patent/PT83044B/pt unknown
- 1986-07-24 KR KR1019860006011A patent/KR920001671B1/ko not_active Expired
- 1986-07-24 ES ES8600566A patent/ES2000936A6/es not_active Expired
- 1986-07-24 JP JP61174684A patent/JPS6277381A/ja active Pending
-
1989
- 1989-02-21 US US07/312,172 patent/US4957609A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT83044A (en) | 1986-08-01 |
| DE3684235D1 (de) | 1992-04-16 |
| JPS6277381A (ja) | 1987-04-09 |
| CA1281721C (en) | 1991-03-19 |
| FI84351B (fi) | 1991-08-15 |
| FI863020A0 (fi) | 1986-07-23 |
| ATE73452T1 (de) | 1992-03-15 |
| EP0221629B1 (en) | 1992-03-11 |
| KR920001671B1 (ko) | 1992-02-22 |
| GB8518742D0 (en) | 1985-08-29 |
| ES2000936A6 (es) | 1988-04-01 |
| KR870001199A (ko) | 1987-03-12 |
| GR861927B (en) | 1986-09-05 |
| US4957609A (en) | 1990-09-18 |
| FI863020L (fi) | 1987-01-25 |
| FI84351C (fi) | 1991-11-25 |
| EP0221629A1 (en) | 1987-05-13 |
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