PT82153A - Process for the preparation of 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and hydrates and pharmaceutically acceptable salts thereof - Google Patents
Process for the preparation of 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and hydrates and pharmaceutically acceptable salts thereofInfo
- Publication number
- PT82153A PT82153A PT82153A PT8215386A PT82153A PT 82153 A PT82153 A PT 82153A PT 82153 A PT82153 A PT 82153A PT 8215386 A PT8215386 A PT 8215386A PT 82153 A PT82153 A PT 82153A
- Authority
- PT
- Portugal
- Prior art keywords
- pyrrolidinyl
- hydrates
- cyclopropyl
- dihydro
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60046216A JPS61205258A (ja) | 1985-03-08 | 1985-03-08 | キノロンカルボン酸誘導体及びその製造方法 |
JP61022296A JPS61225181A (ja) | 1986-02-04 | 1986-02-04 | キノロンカルボン酸誘導体及びその製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT82153A true PT82153A (en) | 1986-04-01 |
PT82153B PT82153B (pt) | 1988-02-17 |
Family
ID=26359486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT82153A PT82153B (pt) | 1985-03-08 | 1986-03-07 | Processo para a preparacao de acido 7-(3-amino-1-pirrolidinil)-8-cloro-1-ciclopropil-6-fluor-1,4-dihidro-4-oxo-3-quinolino-carboxilico e seus hidratos e sais farmaceuticamente aceitaveis |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0195316A1 (pt) |
KR (1) | KR930011036B1 (pt) |
CN (1) | CN1012613B (pt) |
AU (1) | AU5427286A (pt) |
DK (1) | DK161383C (pt) |
ES (1) | ES8704932A1 (pt) |
FI (1) | FI85698C (pt) |
HU (1) | HUT40639A (pt) |
MX (1) | MX162668A (pt) |
NO (1) | NO165071C (pt) |
PT (1) | PT82153B (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4771054A (en) * | 1985-01-23 | 1988-09-13 | Warner-Lambert Company | Antibacterial agents |
US4791225A (en) * | 1986-01-20 | 1988-12-13 | Kyorin Pharmaceutical Co., Ltd. | Halogenobenzoic acid derivatives and their preparation |
JPS63179856A (ja) * | 1987-01-21 | 1988-07-23 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸誘導体の製造方法並びにその中間体 |
JPH01175935A (ja) * | 1987-12-28 | 1989-07-12 | Kyorin Pharmaceut Co Ltd | 凍結乾燥注射剤 |
MY105136A (en) * | 1988-04-27 | 1994-08-30 | Daiichi Seiyaku Co | Optically active pyridonecarboxylic acid derivatives. |
US5233091A (en) * | 1988-06-21 | 1993-08-03 | Pfizer Inc. | 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor |
US4885386A (en) * | 1988-10-28 | 1989-12-05 | Warner-Lambert Company | Process for the synthesis of 3-chloro-2,4,5-trifluorobenzoic acid |
DE3910920A1 (de) * | 1989-04-05 | 1990-10-11 | Bayer Ag | Enantiomerenreine 7-(3-amino-1-pyrrolidinyl)-chinolon- und -naphthyridoncarbonsaeuren |
DE3918544A1 (de) * | 1989-06-07 | 1990-12-13 | Bayer Ag | Verfahren zur herstellung von 7-(3-amino- sowie 3-amino-methyl-1-pyrrolidinyl)-3-chinolon- carbonsaeuren sowie -naphthyridoncarbonsaeuren |
ES2018977A6 (es) * | 1989-11-29 | 1991-05-16 | Marga Investigacion | Procedimiento de preparacion de n-ciclopropil-4-fluoroanilinas. |
SK286420B6 (sk) | 1997-09-15 | 2008-09-05 | The Procter & Gamble Company | Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie |
CA2647454A1 (en) | 2006-03-28 | 2007-10-04 | The Procter & Gamble Company | A coupling process for preparing quinolone intermediates |
BRPI0709772B8 (pt) | 2006-03-28 | 2021-05-25 | The Protecter & Gamble Company | sais de malato e polimorfos do ácido (3s,5s)-7-[3-amino-5-metil-piperidinil]-1-ciclopropil-1,4-diidro-8-metóxi-4-oxo-3-quinolinocarboxílico |
US7902227B2 (en) * | 2007-07-27 | 2011-03-08 | Janssen Pharmaceutica Nv. | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents |
GB201708606D0 (en) * | 2017-05-30 | 2017-07-12 | King's College London | Antibiotic resistance breakers |
CN109293503B (zh) * | 2018-11-06 | 2022-02-01 | 浙江工业大学上虞研究院有限公司 | 一种2,4,5-三氟-3-氯苯甲酸的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5630964A (en) * | 1979-08-22 | 1981-03-28 | Kyorin Pharmaceut Co Ltd | Novel substituted quinolinecarboxylic acid and its preparation |
US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
IE55898B1 (en) * | 1982-09-09 | 1991-02-14 | Warner Lambert Co | Antibacterial agents |
JPS60123837A (ja) * | 1983-12-09 | 1985-07-02 | Mitsubishi Paper Mills Ltd | ハロゲン化銀写真乳剤 |
-
1986
- 1986-03-04 AU AU54272/86A patent/AU5427286A/en not_active Abandoned
- 1986-03-04 HU HU86888A patent/HUT40639A/hu unknown
- 1986-03-06 EP EP86102938A patent/EP0195316A1/en not_active Ceased
- 1986-03-06 FI FI860950A patent/FI85698C/fi not_active IP Right Cessation
- 1986-03-07 DK DK103986A patent/DK161383C/da not_active IP Right Cessation
- 1986-03-07 MX MX1780A patent/MX162668A/es unknown
- 1986-03-07 ES ES552802A patent/ES8704932A1/es not_active Expired
- 1986-03-07 CN CN86102363A patent/CN1012613B/zh not_active Expired
- 1986-03-07 PT PT82153A patent/PT82153B/pt unknown
- 1986-03-07 NO NO860870A patent/NO165071C/no unknown
- 1986-03-08 KR KR1019860001648A patent/KR930011036B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI860950A (fi) | 1986-09-09 |
DK161383B (da) | 1991-07-01 |
DK161383C (da) | 1991-12-09 |
KR860007249A (ko) | 1986-10-10 |
EP0195316A1 (en) | 1986-09-24 |
AU5427286A (en) | 1986-09-11 |
MX162668A (es) | 1991-06-14 |
DK103986A (da) | 1986-09-09 |
CN86102363A (zh) | 1987-01-21 |
ES552802A0 (es) | 1987-04-16 |
KR930011036B1 (ko) | 1993-11-20 |
PT82153B (pt) | 1988-02-17 |
FI85698B (fi) | 1992-02-14 |
DK103986D0 (da) | 1986-03-07 |
FI85698C (fi) | 1992-05-25 |
CN1012613B (zh) | 1991-05-15 |
FI860950A0 (fi) | 1986-03-06 |
HUT40639A (en) | 1987-01-28 |
NO165071C (no) | 1990-12-19 |
NO860870L (no) | 1986-09-09 |
ES8704932A1 (es) | 1987-04-16 |
NO165071B (no) | 1990-09-10 |
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