ES2018977A6 - Procedimiento de preparacion de n-ciclopropil-4-fluoroanilinas. - Google Patents
Procedimiento de preparacion de n-ciclopropil-4-fluoroanilinas.Info
- Publication number
- ES2018977A6 ES2018977A6 ES898904064A ES8904064A ES2018977A6 ES 2018977 A6 ES2018977 A6 ES 2018977A6 ES 898904064 A ES898904064 A ES 898904064A ES 8904064 A ES8904064 A ES 8904064A ES 2018977 A6 ES2018977 A6 ES 2018977A6
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- preparation
- fluoroanilines
- cyclopropyl
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/52—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE N-CICLOPROPIL-4-FLUORANILINAS DE FORMULA (I). POR REACCION SELECTIVA DE (II) CON CICLOPROPILAMINA, PIPERACINAS O PIRROLIDINAS SE OBTIENE (III). SU ACETILACION Y REDUCCION RINDE (IV) QUE POR DESAMINACION CONDUCE A (I). RBS1 ES HIDROGENO, CLORO O METILO, RBS2 HIDROGENO, HALOGENO, METILO, UN PIPERACINILO O UN PIRROLIDINILO, RBS3 HIDROGENO, HALOGENO, HIDROXILO O TRIFLUOROMETILO Y RBS4 HIDROGENO, NITRO, HIDROXILO O AMINO. LOS COMPUESTOS DE FORMULA (I) SON DE INTERES POR SU APLICACION A LA PREPARACION DE ANTIBIOTICOS DEL GRUPO DE LAS QUINOLONAS.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES898904064A ES2018977A6 (es) | 1989-11-29 | 1989-11-29 | Procedimiento de preparacion de n-ciclopropil-4-fluoroanilinas. |
EP90500109A EP0430847A1 (en) | 1989-11-29 | 1990-11-28 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES898904064A ES2018977A6 (es) | 1989-11-29 | 1989-11-29 | Procedimiento de preparacion de n-ciclopropil-4-fluoroanilinas. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2018977A6 true ES2018977A6 (es) | 1991-05-16 |
Family
ID=8265072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES898904064A Expired - Lifetime ES2018977A6 (es) | 1989-11-29 | 1989-11-29 | Procedimiento de preparacion de n-ciclopropil-4-fluoroanilinas. |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP0430847A1 (es) |
ES (1) | ES2018977A6 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2701090B2 (ja) * | 1990-11-30 | 1998-01-21 | 和光純薬工業株式会社 | 被酸化性呈色試薬 |
US6353140B1 (en) | 2000-10-19 | 2002-03-05 | Eastman Chemical Company | Process for the purification of cyclopropanecarboxaldehyde |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN162769B (es) * | 1984-11-13 | 1988-07-09 | Kyorin Seiyaku Kk | |
JPH0649671B2 (ja) * | 1984-12-17 | 1994-06-29 | 杏林製薬株式会社 | アニリン類とその製造方法 |
HUT40639A (en) * | 1985-03-08 | 1987-01-28 | Kyorin Seiyaku Kk | Process for producing quinolon-carboxylic acid derivative and pharmaceutical composition containing them |
DE3705621C2 (de) * | 1986-02-25 | 1997-01-09 | Otsuka Pharma Co Ltd | Heterocyclisch substituierte Chinoloncarbonsäurederivate |
-
1989
- 1989-11-29 ES ES898904064A patent/ES2018977A6/es not_active Expired - Lifetime
-
1990
- 1990-11-28 EP EP90500109A patent/EP0430847A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP0430847A1 (en) | 1991-06-05 |
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