PT81168B - Processo para a preparacao de proteinas inibidoras da coagulacao do sangue e de composicoes farmaceuticas contendo estas substancias - Google Patents
Processo para a preparacao de proteinas inibidoras da coagulacao do sangue e de composicoes farmaceuticas contendo estas substanciasInfo
- Publication number
- PT81168B PT81168B PT81168A PT8116885A PT81168B PT 81168 B PT81168 B PT 81168B PT 81168 A PT81168 A PT 81168A PT 8116885 A PT8116885 A PT 8116885A PT 81168 B PT81168 B PT 81168B
- Authority
- PT
- Portugal
- Prior art keywords
- substances
- preparation
- pharmaceutical compositions
- compositions containing
- blood coagulation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8402904A NL8402904A (nl) | 1984-09-21 | 1984-09-21 | De bloedstolling remmend eiwitmateriaal, werkwijze voor het isoleren daarvan alsmede farmaceutisch preparaat. |
NL8500601A NL8500601A (nl) | 1985-03-04 | 1985-03-04 | Uit biologisch materiaal isoleerbaar, de bloedstolling remmend eiwitmateriaal, werkwijzen voor het isoleren en zuiveren daarvan alsmede farmaceutisch preparaat. |
Publications (2)
Publication Number | Publication Date |
---|---|
PT81168A PT81168A (de) | 1985-10-01 |
PT81168B true PT81168B (pt) | 1988-01-22 |
Family
ID=26645980
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT81168A PT81168B (pt) | 1984-09-21 | 1985-09-20 | Processo para a preparacao de proteinas inibidoras da coagulacao do sangue e de composicoes farmaceuticas contendo estas substancias |
Country Status (17)
Country | Link |
---|---|
US (2) | US4736018A (pt) |
EP (1) | EP0181465B2 (pt) |
JP (1) | JPH0780912B2 (pt) |
KR (1) | KR930007434B1 (pt) |
AU (1) | AU596951B2 (pt) |
CA (1) | CA1244763A (pt) |
DE (2) | DE3572179D1 (pt) |
DK (1) | DK166587B1 (pt) |
ES (1) | ES8702431A1 (pt) |
FI (1) | FI83882C (pt) |
HU (1) | HU199883B (pt) |
IE (1) | IE58862B1 (pt) |
IL (1) | IL76441A (pt) |
NO (1) | NO164991C (pt) |
NZ (1) | NZ213563A (pt) |
PH (1) | PH23942A (pt) |
PT (1) | PT81168B (pt) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE113062T1 (de) * | 1986-07-15 | 1994-11-15 | Kowa Co | Throminbindende substanz und verfahren zu ihrer herstellung. |
US4962022A (en) * | 1986-09-22 | 1990-10-09 | Becton Dickinson And Company | Storage and use of liposomes |
JPH08840B2 (ja) * | 1986-11-14 | 1996-01-10 | 興和株式会社 | 抗pciモノクローナル抗体、これを用いた抗pciの精製法及び免疫学的測定法 |
US4937324A (en) * | 1987-02-06 | 1990-06-26 | Zymogenetics, Inc. | Chromatographic purification of human proteins having anticoagulant and anti-inflammatory activity |
DE3710364A1 (de) * | 1987-03-28 | 1989-01-19 | Boehringer Ingelheim Int | Vascular-antikoagulierende proteine, dna die diese kodieren, verfahren zu deren herstellung sowie deren verwendung |
DE3737367A1 (de) * | 1987-11-04 | 1989-05-24 | Boehringer Ingelheim Int | Vascular-antikoagulierende proteine, dna die diese kodieren, verfahren zu deren herstellung sowie deren verwendung |
PT87083B (pt) * | 1987-03-28 | 1992-07-31 | Boehringer Ingelheim Int | Processo para a preparacao de uma proteina anticoagulante vascular, de adn que codifica para esta proteina e de composicoes farmaceuticas que a contem |
DE3710430A1 (de) * | 1987-03-28 | 1989-01-19 | Boehringer Ingelheim Int | Vascular-antikoagulierende proteine, dna die diese kodieren, verfahren zu deren herstellung sowie deren verwendung |
DE3724726A1 (de) * | 1987-07-25 | 1989-02-02 | Behringwerke Ag | Verfahren zur reinigung des plazentaren gewebeproteins pp4 |
US5187155A (en) * | 1989-06-23 | 1993-02-16 | Board Of Regents, The University Of Texas System | Anticoagulant peptides |
ES2045669T3 (es) * | 1989-07-15 | 1994-01-16 | Boehringer Ingelheim Int | Procedimiento para la purificacion de anexinas. |
DE59001418D1 (de) * | 1989-07-15 | 1993-06-17 | Boehringer Ingelheim Int | Antikoagulanz enthaltendes mittel. |
US5190919A (en) * | 1989-11-13 | 1993-03-02 | Board Of Regents, The University Of Texas System | Antihemostatic factor vii peptides |
US5627036A (en) * | 1989-12-27 | 1997-05-06 | Boehringer Ingelheim International Gmbh | Use of an anticoagulant as a diagnostic agent |
IE73210B1 (en) * | 1990-01-24 | 1997-05-07 | Warner Lambert Co | Process for the production of thrombin and high purity thrombin preparation thereby obtained |
WO1993007491A1 (en) * | 1991-10-04 | 1993-04-15 | Board Of Regents Of The University Of Nebraska | A soluble thrombomodulin-based one-stage assay for vitamin k-dependent coagulation-inhibiting proteins |
US5716795A (en) * | 1991-10-04 | 1998-02-10 | Matschiner; John T. | Thrombomodulin-based coagulometric assay of the protein C system |
US5266462A (en) * | 1992-06-03 | 1993-11-30 | Baxter Diagnostics Inc. | Measurement of platelet activities |
JPH078298A (ja) * | 1993-06-28 | 1995-01-13 | Nippon Shoji Kk | アンチトロンビンiii活性の測定方法および該測定用試薬キット |
US5455338A (en) * | 1993-11-05 | 1995-10-03 | Zymogenetics, Inc. | DNA encoding novel human kunitz-type inhibitors and methods relating thereto |
US5968477A (en) * | 1994-01-24 | 1999-10-19 | Neorx Corporation | Radiolabeled annexin conjugates with hexose and a chelator |
US20030220233A1 (en) | 1994-01-24 | 2003-11-27 | Neorx Corporation | Radiolabeled annexins |
US5985582A (en) * | 1997-12-09 | 1999-11-16 | Sigma-Aldrich Co. | Thrombin-based assay for antithrombin III |
EP1192270A2 (en) | 1999-06-14 | 2002-04-03 | Novo Nordisk A/S | FVIIa/TF ACTIVITY INHIBITING COMPOUNDS |
US7635676B2 (en) * | 2001-02-21 | 2009-12-22 | Alavita Pharmaccuticals, Inc. | Modified annexin proteins and methods for their use in organ transplantation |
EP1379266B1 (en) * | 2001-02-21 | 2007-04-18 | SurroMed, Inc. | Modified annexin proteins and prevention and treatment of thrombosis |
US20090291086A1 (en) * | 2001-02-21 | 2009-11-26 | Alavita Pharmaceuticals, Inc. | Compositions and Methods for Treating Cerebral Thrombosis and Global Cerebral Ischemia |
US7645739B2 (en) * | 2001-02-21 | 2010-01-12 | Alavita Pharmaceuticals, Inc. | Modified annexin compositions and methods of using same |
US7635680B2 (en) * | 2001-02-21 | 2009-12-22 | Alavita Pharmaceuticals, Inc. | Attenuation of reperfusion injury |
CN100567487C (zh) | 2001-03-22 | 2009-12-09 | 诺沃挪第克健康护理股份公司 | 凝血因子vii衍生物 |
US8364342B2 (en) * | 2001-07-31 | 2013-01-29 | Immersion Corporation | Control wheel with haptic feedback |
US6982154B2 (en) | 2002-02-21 | 2006-01-03 | Surromed, Inc. | Modified annexin proteins and methods for treating vaso-occlusive sickle-cell disease |
US7029468B2 (en) * | 2002-06-25 | 2006-04-18 | Enpath Medical, Inc. | Catheter assembly with side wall exit lumen and method therefor |
US20080269857A1 (en) * | 2007-04-30 | 2008-10-30 | Cross Thomas E | Implantable medical leads and lead assemblies with flexibility, extensibility and branched structures |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3904480A (en) * | 1972-10-24 | 1975-09-09 | Lilly Co Eli | Enhanced production of plasminogen activator |
IL43343A (en) * | 1972-10-24 | 1976-03-31 | Lilly Co Eli | Production of plasminogen activator |
US4347243A (en) * | 1979-10-04 | 1982-08-31 | Research Corporation | Acid soluble, pepsin resistant platelet aggregating material |
DE3038163A1 (de) * | 1980-10-09 | 1982-05-06 | Boehringer Mannheim Gmbh, 6800 Mannheim | Thrombininhibitor, seine herstellung und verwendung |
AU1516483A (en) * | 1982-04-28 | 1983-11-21 | Gray Charles Richardson White | Blood products and processes for their production |
US4757134A (en) * | 1982-12-02 | 1988-07-12 | The Rockefeller University | IgA binding protein |
DE3315000A1 (de) * | 1983-04-26 | 1984-10-31 | Behringwerke Ag, 3550 Marburg | Gewebeprotein pp(pfeil abwaerts)4(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung |
JPS60199819A (ja) * | 1984-03-23 | 1985-10-09 | Kowa Co | トロンビン結合性物質およびその製法 |
DE3418888A1 (de) * | 1984-05-21 | 1985-11-21 | Behringwerke Ag, 3550 Marburg | Gewebeprotein pp(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung |
JPH0689014B2 (ja) * | 1986-01-21 | 1994-11-09 | 興和株式会社 | トロンビン結合性物質およびその製法 |
DE3710430A1 (de) * | 1987-03-28 | 1989-01-19 | Boehringer Ingelheim Int | Vascular-antikoagulierende proteine, dna die diese kodieren, verfahren zu deren herstellung sowie deren verwendung |
DE3737239A1 (de) * | 1987-11-03 | 1989-10-12 | Behringwerke Ag | Gentechnische herstellung von anticoagulatorischem protein pp4 |
-
1985
- 1985-09-20 HU HU853552A patent/HU199883B/hu unknown
- 1985-09-20 FI FI853611A patent/FI83882C/fi not_active IP Right Cessation
- 1985-09-20 DE DE8585111887T patent/DE3572179D1/de not_active Expired
- 1985-09-20 DK DK427485A patent/DK166587B1/da not_active IP Right Cessation
- 1985-09-20 EP EP85111887A patent/EP0181465B2/de not_active Expired - Lifetime
- 1985-09-20 NZ NZ213563A patent/NZ213563A/xx unknown
- 1985-09-20 KR KR1019850006891A patent/KR930007434B1/ko not_active IP Right Cessation
- 1985-09-20 NO NO853700A patent/NO164991C/no not_active IP Right Cessation
- 1985-09-20 PT PT81168A patent/PT81168B/pt unknown
- 1985-09-20 JP JP60208573A patent/JPH0780912B2/ja not_active Expired - Lifetime
- 1985-09-20 IL IL76441A patent/IL76441A/xx not_active IP Right Cessation
- 1985-09-20 DE DE19853533516 patent/DE3533516A1/de not_active Ceased
- 1985-09-20 IE IE232385A patent/IE58862B1/en not_active IP Right Cessation
- 1985-09-20 CA CA000491206A patent/CA1244763A/en not_active Expired
- 1985-09-20 ES ES547139A patent/ES8702431A1/es not_active Expired
- 1985-09-23 US US06/779,287 patent/US4736018A/en not_active Expired - Lifetime
- 1985-09-23 PH PH32821A patent/PH23942A/en unknown
- 1985-09-23 AU AU47682/85A patent/AU596951B2/en not_active Expired
-
1987
- 1987-11-23 US US07/123,970 patent/US5066787A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE3572179D1 (en) | 1989-09-14 |
DK427485D0 (da) | 1985-09-20 |
AU596951B2 (en) | 1990-05-24 |
NO853700L (no) | 1986-03-24 |
DK166587B1 (da) | 1993-06-14 |
EP0181465A1 (de) | 1986-05-21 |
FI83882B (fi) | 1991-05-31 |
IE58862B1 (en) | 1993-11-17 |
JPS61137822A (ja) | 1986-06-25 |
NZ213563A (en) | 1991-08-27 |
FI853611A0 (fi) | 1985-09-20 |
FI853611L (fi) | 1986-03-22 |
FI83882C (fi) | 1991-09-10 |
EP0181465B2 (de) | 1994-11-23 |
NO164991B (no) | 1990-08-27 |
IL76441A0 (en) | 1986-01-31 |
EP0181465B1 (de) | 1989-08-09 |
AU4768285A (en) | 1986-03-27 |
IE852323L (en) | 1986-03-21 |
ES8702431A1 (es) | 1986-12-16 |
IL76441A (en) | 1990-07-26 |
KR860002567A (ko) | 1986-04-26 |
HUT39466A (en) | 1986-09-29 |
JPH0780912B2 (ja) | 1995-08-30 |
ES547139A0 (es) | 1986-12-16 |
PT81168A (de) | 1985-10-01 |
NO164991C (no) | 1990-12-05 |
US4736018A (en) | 1988-04-05 |
KR930007434B1 (ko) | 1993-08-10 |
DE3533516A1 (de) | 1986-04-03 |
US5066787A (en) | 1991-11-19 |
CA1244763A (en) | 1988-11-15 |
HU199883B (en) | 1990-03-28 |
PH23942A (en) | 1990-01-23 |
DK427485A (da) | 1986-03-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT81168B (pt) | Processo para a preparacao de proteinas inibidoras da coagulacao do sangue e de composicoes farmaceuticas contendo estas substancias | |
PT82993B (pt) | Processo para a preparacao de novos polipeptidos com accao de inibicao da coagulacao do sangue e de composicoes farmaceuticas que os contem | |
PT89094A (pt) | Processo para a preparacao de 1-aril-3-quinolina-e 1-aril-3-isoquinolina-carboxamidas e de composicoes farmaceuticas que as contem | |
PT91731A (pt) | Processo para a preparacao de composicoes farmaceuticas contendo ciclosporinas | |
PT84449B (pt) | Processo para a preparacao de novos derivados 3,5-dissubstituidos do pirocatecol e de composicoes farmaceuticas que os contem | |
PT87259A (pt) | Processo para a preparacao de composicoes farmaceuticas contendo 17-cetoesteroides apropriadas para o tratamento e a profilaxia de infeccoes retrovirais | |
PT84790B (pt) | Processo de preparacao de derivados de amino-tiazol e de amino-oxazole e de composicoes farmaceuticas contendo-os | |
PT84702B (pt) | Processo para a preparacao de 1-hidroxi-2-piridonas, de composicoes farmaceuticas que as contem e dos produtos intermediarios para a sua preparacao | |
PT87237A (pt) | Process for the preparation of bifunctional proteins and of pharmaceutical compounds containing them | |
PT84681B (pt) | Processo para a preparacao de carboxamidas heterociclicas e de composicoes farmaceuticas que as contem | |
PT87470A (pt) | Process for the preparation of novel substituted benzamides and of pharmaceutical compositions containing the same | |
PT84462B (pt) | Rocesso para a preparacao de novos tiazois e oxazois substituidos e de composicoes farmaceuticas que os contem | |
PT81531B (pt) | Processo para a preparacao de silibinina isenta de isosilibina e de composicoes farmaceuticas contendo silibinina | |
PT83260B (pt) | Processo para a preparacao de compostos derivados da espergualina e de composicoes farmaceuticas que os contem | |
PT84187B (pt) | Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem | |
PT94225A (pt) | Processo para a preparacao de novos compostos derivados de cromano e de composicoes farmaceuticas que os contem | |
PT83604B (pt) | Processo para a preparacao de derivados da flavona e de composicoes farmaceuticas que os contem | |
PT94792A (pt) | Processo para a preparacao de novos compostos derivados de cromano e de composicoes farmaceuticas que os contem | |
PT82440B (pt) | Processo para a preparacao de eteres ciclopentilicos e de composicoes farmaceuticas que os contem | |
PT88351A (pt) | Processo para a preparacao de derivados de isoxazol-beta-carbolina e de composicoes farmaceuticas que os contem | |
PT90904A (pt) | Processo para a preparacao de derivados de 3-oxo-propanonitrilo triciclicos e de composicoes farmaceuticas que os contem | |
PT90721A (pt) | Processo para a preparacao de compostos de imidazoquinoxalina e de composicoes farmaceuticas que os contem | |
PT82167B (pt) | Processo para a preparacao de sulfureto heterociclicos e de composicoes farmceuticas que os contem | |
PT91787A (pt) | Processo para a preparacao de tienopiranos substituidos e de composicoes farmaceuticas que os contem | |
PT82765A (pt) | Processo para a preparacao de factor supressor activante e de composicoes farmaceuticas para o tratamento de doencas auto-imines |