PT793666E - Processo de sililacao - Google Patents
Processo de sililacaoInfo
- Publication number
- PT793666E PT793666E PT95940215T PT95940215T PT793666E PT 793666 E PT793666 E PT 793666E PT 95940215 T PT95940215 T PT 95940215T PT 95940215 T PT95940215 T PT 95940215T PT 793666 E PT793666 E PT 793666E
- Authority
- PT
- Portugal
- Prior art keywords
- pct
- desacetoxy
- aminoacyl
- silylation
- sec
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000006884 silylation reaction Methods 0.000 abstract 2
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 1
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 1
- NVIAYEIXYQCDAN-CLZZGJSISA-N 7beta-aminodeacetoxycephalosporanic acid Chemical compound S1CC(C)=C(C(O)=O)N2C(=O)[C@@H](N)[C@@H]12 NVIAYEIXYQCDAN-CLZZGJSISA-N 0.000 abstract 1
- 150000001733 carboxylic acid esters Chemical class 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cephalosporin Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Vibration Prevention Devices (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9423459A GB9423459D0 (en) | 1994-11-21 | 1994-11-21 | Silylation process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT793666E true PT793666E (pt) | 2002-09-30 |
Family
ID=10764738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT95940215T PT793666E (pt) | 1994-11-21 | 1995-11-20 | Processo de sililacao |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5998610A (pt) |
| EP (1) | EP0793666B1 (pt) |
| JP (2) | JP3072857B2 (pt) |
| KR (1) | KR100416673B1 (pt) |
| CN (2) | CN1062272C (pt) |
| AT (1) | ATE216702T1 (pt) |
| AU (1) | AU4174496A (pt) |
| DE (1) | DE69526519T2 (pt) |
| ES (1) | ES2176349T3 (pt) |
| GB (1) | GB9423459D0 (pt) |
| HU (1) | HUT77102A (pt) |
| PL (1) | PL184270B1 (pt) |
| PT (1) | PT793666E (pt) |
| SI (1) | SI0793666T1 (pt) |
| TW (1) | TW432070B (pt) |
| WO (1) | WO1996016067A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001023393A1 (fr) * | 1999-09-30 | 2001-04-05 | Otsuka Kagaku Kabushiki Kaisha | Cristaux obtenus a partir d'un derive de 3-cepheme et methode de preparation |
| US20040077849A1 (en) * | 2002-10-16 | 2004-04-22 | Orchid Chemicals & Pharmaceuticals Limited | Process for the preparation of cefadroxil |
| US7534781B2 (en) * | 2003-03-21 | 2009-05-19 | Dsm Ip Assets B.V. | Crystalline amoxicillin trihydrate powder |
| BRPI0408403A (pt) * | 2003-03-21 | 2006-03-21 | Dsm Ip Assets Bv | pó cristalino de triidrato de amoxicilina |
| CN101772509B (zh) * | 2007-07-30 | 2013-12-04 | 中化帝斯曼制药有限公司荷兰公司 | 用于β-内酰胺化合物的硅烷基化的方法 |
| CN101845053B (zh) * | 2010-03-09 | 2012-07-25 | 河北科技大学 | 一种分离提纯阿莫西林三水化合物的方法 |
| CN103183685B (zh) * | 2011-12-30 | 2016-03-30 | 浙江新和成股份有限公司 | 6α-酰胺基青霉烷酸亚砜化合物的制备方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE311519B (pt) * | 1962-12-14 | 1969-06-16 | Astra Ab | |
| US4093803A (en) * | 1971-05-14 | 1978-06-06 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(thienyl-, furyl- or pyridylacetamido)] cephalosporins |
| US4138555A (en) * | 1971-05-14 | 1979-02-06 | Glaxo Laboratories, Limited | (6R,7R)-7-[2-aryl-2-(etherified oximino)acetamido]-3-carbamoyloxymethylceph-3-em-4-carboxylic acid 1-oxides |
| DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
| GB1459807A (en) * | 1975-05-27 | 1976-12-31 | Proter Spa | Process for the production of 7-d-a-amino-phenyl-acetamido-3- desacetoxy-cephalosporanic acid |
| US5336776A (en) * | 1976-01-23 | 1994-08-09 | Roussel Uclaf | 3-acetoxymethyl-7-(iminoacetamideo)-cephalosporanic acid |
| US4196205A (en) * | 1976-01-23 | 1980-04-01 | Roussel Uclaf | 3-Acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives |
| US5079369A (en) * | 1976-04-12 | 1992-01-07 | Fujisawa Pharmaceutical Company, Ltd. | Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof |
| DE2760484C2 (pt) * | 1976-04-14 | 1992-12-03 | Takeda Chemical Industries, Ltd., Osaka, Jp | |
| GB1532682A (en) * | 1976-04-27 | 1978-11-22 | Bristol Myers Co | Process for the preparation of cephadroxil |
| DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
| GB2001985B (en) * | 1977-08-05 | 1982-07-07 | Lark Spa | Process for the preparation of penicillanic and cephalosporanic acid derivatives |
| FR2400519A1 (fr) * | 1977-08-17 | 1979-03-16 | Roussel Uclaf | Forme cristalline du sel de sodium d'un derive oximine de l'acide 7-amino-thiazolyl acetamido cephalosporanique, son procede de preparation et son application comme medicament |
| NL162387C (nl) * | 1977-09-06 | 1980-05-16 | Gist Brocades Nv | Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur. |
| JPS5459296A (en) * | 1977-10-14 | 1979-05-12 | Toshin Chemical Co | Production of alphaaaminoo paraahydroxybenzylpeniciline |
| CA1125745A (en) * | 1978-11-20 | 1982-06-15 | Joseph Kaspi | PROCESS FOR PREPARING .beta.-LACTAM ANTIBIOTICS |
| IT1126544B (it) * | 1979-12-07 | 1986-05-21 | Dobfar Spa | Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico |
| EP0037380B1 (en) * | 1980-03-28 | 1984-09-12 | BIOCHEMIE Gesellschaft m.b.H. | New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production |
| IT1180207B (it) * | 1984-07-30 | 1987-09-23 | Istituto Biochimico Italiano | Procedimento per la preparazione, con resa e purezza elevate, di antibiotici beta-lattamici |
| DE3539901A1 (de) * | 1985-11-11 | 1987-05-14 | Hoechst Ag | Cephalosporinderivate und verfahren zu ihrer herstellung |
| IT1214587B (it) * | 1986-12-23 | 1990-01-18 | Giovanni Bonfanti | Metodo per la produzione diprodotti cristallini puri. |
| ES2006988A6 (es) * | 1988-06-20 | 1989-05-16 | Gema Sa | Procedimiento de preparar hidrocloruro cloruro-2-(2-aminotiazol-4-il)-2-metoxiiminoacetil-sulfito-dimetilformiminio y procedimiento de utilizacion del mismo para obtencion de amidas. |
| US5034522A (en) * | 1988-08-02 | 1991-07-23 | Biocraft Laboratories, Inc. | Method for the production of 3-methyl cephem derivatives |
| HU221200B1 (en) * | 1990-01-22 | 2002-08-28 | Biochemie Gmbh | Process for producing beta-lactames |
| CA2033692A1 (en) * | 1990-01-25 | 1991-07-26 | Wilhelm Bannwarth | Energy transfer systems |
| US5142043A (en) * | 1990-05-10 | 1992-08-25 | Biocraft Laboratories, Inc. | Process for preparing cephalexin monohydrate |
| US5574154A (en) * | 1994-09-29 | 1996-11-12 | Alnejma Bulk Pharmaceutical Co. A.B.P.C. | Process for the preparation of cephalosporanic compounds |
-
1994
- 1994-11-21 GB GB9423459A patent/GB9423459D0/en active Pending
-
1995
- 1995-11-02 US US08/836,776 patent/US5998610A/en not_active Expired - Fee Related
- 1995-11-20 DE DE69526519T patent/DE69526519T2/de not_active Expired - Fee Related
- 1995-11-20 WO PCT/EP1995/004562 patent/WO1996016067A1/en active IP Right Grant
- 1995-11-20 PL PL95319752A patent/PL184270B1/pl not_active IP Right Cessation
- 1995-11-20 KR KR1019970703336A patent/KR100416673B1/ko not_active IP Right Cessation
- 1995-11-20 CN CN95196352A patent/CN1062272C/zh not_active Expired - Fee Related
- 1995-11-20 PT PT95940215T patent/PT793666E/pt unknown
- 1995-11-20 JP JP08516566A patent/JP3072857B2/ja not_active Expired - Fee Related
- 1995-11-20 TW TW084112300A patent/TW432070B/zh not_active IP Right Cessation
- 1995-11-20 SI SI9530598T patent/SI0793666T1/xx unknown
- 1995-11-20 HU HU9701868A patent/HUT77102A/hu unknown
- 1995-11-20 ES ES95940215T patent/ES2176349T3/es not_active Expired - Lifetime
- 1995-11-20 EP EP95940215A patent/EP0793666B1/en not_active Expired - Lifetime
- 1995-11-20 AU AU41744/96A patent/AU4174496A/en not_active Abandoned
- 1995-11-20 AT AT95940215T patent/ATE216702T1/de not_active IP Right Cessation
-
1999
- 1999-11-24 JP JP11333242A patent/JP2000229986A/ja active Pending
- 1999-12-30 CN CN99127526A patent/CN1124277C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1062272C (zh) | 2001-02-21 |
| DE69526519D1 (de) | 2002-05-29 |
| GB9423459D0 (en) | 1995-01-11 |
| PL319752A1 (en) | 1997-08-18 |
| EP0793666B1 (en) | 2002-04-24 |
| TW432070B (en) | 2001-05-01 |
| JP3072857B2 (ja) | 2000-08-07 |
| ATE216702T1 (de) | 2002-05-15 |
| KR100416673B1 (ko) | 2004-03-18 |
| EP0793666A1 (en) | 1997-09-10 |
| JP2000229986A (ja) | 2000-08-22 |
| AU4174496A (en) | 1996-06-17 |
| WO1996016067A1 (en) | 1996-05-30 |
| HUT77102A (hu) | 1998-03-02 |
| CN1164235A (zh) | 1997-11-05 |
| US5998610A (en) | 1999-12-07 |
| CN1280982A (zh) | 2001-01-24 |
| KR970707135A (ko) | 1997-12-01 |
| ES2176349T3 (es) | 2002-12-01 |
| JPH10507773A (ja) | 1998-07-28 |
| CN1124277C (zh) | 2003-10-15 |
| PL184270B1 (pl) | 2002-09-30 |
| DE69526519T2 (de) | 2002-10-31 |
| SI0793666T1 (en) | 2002-10-31 |
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