PT78985B - Improvements in or relating to cephalosporins - Google Patents

Improvements in or relating to cephalosporins

Info

Publication number
PT78985B
PT78985B PT78985A PT7898584A PT78985B PT 78985 B PT78985 B PT 78985B PT 78985 A PT78985 A PT 78985A PT 7898584 A PT7898584 A PT 7898584A PT 78985 B PT78985 B PT 78985B
Authority
PT
Portugal
Prior art keywords
cephalosporins
relating
Prior art date
Application number
PT78985A
Other languages
English (en)
Other versions
PT78985A (en
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of PT78985A publication Critical patent/PT78985A/pt
Publication of PT78985B publication Critical patent/PT78985B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT78985A 1983-07-29 1984-07-27 Improvements in or relating to cephalosporins PT78985B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838320521A GB8320521D0 (en) 1983-07-29 1983-07-29 Chemical process

Publications (2)

Publication Number Publication Date
PT78985A PT78985A (en) 1984-08-01
PT78985B true PT78985B (en) 1986-10-23

Family

ID=10546505

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78985A PT78985B (en) 1983-07-29 1984-07-27 Improvements in or relating to cephalosporins

Country Status (21)

Country Link
JP (1) JPH0613526B2 (pt)
KR (1) KR910008377B1 (pt)
AT (1) AT392470B (pt)
AU (2) AU582121B2 (pt)
BE (1) BE900241A (pt)
CA (1) CA1265511A (pt)
CH (1) CH662121A5 (pt)
DE (1) DE3427828A1 (pt)
DK (1) DK165505C (pt)
ES (1) ES534695A0 (pt)
FI (1) FI76808C (pt)
FR (1) FR2549837B1 (pt)
GB (2) GB8320521D0 (pt)
IE (1) IE57726B1 (pt)
IL (1) IL72536A (pt)
NL (1) NL8402372A (pt)
NO (1) NO167292C (pt)
NZ (1) NZ209046A (pt)
PT (1) PT78985B (pt)
SE (1) SE463263B (pt)
ZA (1) ZA845830B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
US5063224A (en) * 1990-07-09 1991-11-05 Eli Lilly And Company R-cefuroxime axetil
IT1277426B1 (it) * 1995-08-03 1997-11-10 Acs Dobfar Spa Forma cristallina biodisponibile del cefuroxima axetil
CN1111537C (zh) * 1997-05-15 2003-06-18 第一制糖株式会社 高纯晶形头孢呋辛1－乙酰氧乙酯的制备方法
KR100228264B1 (ko) * 1997-08-02 1999-11-01 김선진 결정형 세푸록심 악세틸의 제조방법
CA2209868C (en) * 1997-08-15 2001-08-14 Bernard Charles Sherman Pharmaceutical compositions comprising cefuroxime axetil
IN186539B (pt) * 1997-09-29 2001-09-29 Ranbaxy Lab Ltd
ES2171056T3 (es) * 1998-02-20 2002-08-16 Fako Ilaclari A S Procedimiento para la fabricacion de cefuroxima axetil cristalina soluble.
IN190849B (pt) 2000-07-17 2003-08-23 Ranbaxy Lab Ltd
AT411996B (de) 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
ITMI20011763A1 (it) * 2001-08-10 2003-02-10 Antibioticos Spa Processo di preparazione di cefuroxime axelite ad elevata purezza
ITMI20011925A1 (it) * 2001-09-14 2003-03-14 Antibioticos Spa Metodo applicabile su scala industriale per la preparazione di cefuroxime axetile cristallino
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
CN100448879C (zh) * 2004-07-22 2009-01-07 北京化工大学 一种无定型头孢呋辛酯的制备方法
DE102005019458A1 (de) * 2005-04-25 2006-10-26 Grünenthal GmbH Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil
CN118561870A (zh) * 2024-05-15 2024-08-30 广东立国制药有限公司 一种制备头孢呋辛酸的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1094545A (en) * 1976-02-16 1981-01-27 Michael Gregson Cephalosporin antibiotics
GB1571683A (en) * 1976-02-16 1980-07-16 Glaxo Operations Ltd Ester derivatives of cefuroxime
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS577485A (en) * 1980-06-13 1982-01-14 Takeda Chem Ind Ltd Cephalosporin
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics

Also Published As

Publication number Publication date
NZ209046A (en) 1988-02-29
DK165505B (da) 1992-12-07
FI843011A0 (fi) 1984-07-27
FR2549837A1 (fr) 1985-02-01
GB8320521D0 (en) 1983-09-01
CH662121A5 (de) 1987-09-15
IL72536A0 (en) 1984-11-30
SE8403897L (sv) 1985-01-30
DK165505C (da) 1993-04-19
BE900241A (fr) 1985-01-28
SE463263B (sv) 1990-10-29
ZA845830B (en) 1986-03-26
AU3125684A (en) 1985-01-31
PT78985A (en) 1984-08-01
NO843055L (no) 1985-01-30
DK366684D0 (da) 1984-07-27
DK366684A (da) 1985-01-30
ES8601869A1 (es) 1985-11-01
NL8402372A (nl) 1985-02-18
NO167292C (no) 1991-10-23
IE841938L (en) 1985-01-29
AU582121B2 (en) 1989-03-16
GB2145409B (en) 1987-02-18
FR2549837B1 (fr) 1986-12-26
KR850001221A (ko) 1985-03-16
AU634965B2 (en) 1993-03-11
SE8403897D0 (sv) 1984-07-27
FI76808C (fi) 1988-12-12
KR910008377B1 (ko) 1991-10-12
AT392470B (de) 1991-04-10
GB2145409A (en) 1985-03-27
CA1265511A (en) 1990-02-06
JPS6075484A (ja) 1985-04-27
DE3427828A1 (de) 1985-02-14
FI76808B (fi) 1988-08-31
JPH0613526B2 (ja) 1994-02-23
AU3660189A (en) 1989-10-05
IL72536A (en) 1988-01-31
ES534695A0 (es) 1985-11-01
NO167292B (no) 1991-07-15
GB8419202D0 (en) 1984-08-30
IE57726B1 (en) 1993-03-24
ATA244484A (de) 1990-09-15
FI843011L (fi) 1985-01-30

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