GB8419202D0 - Cephalosporins - Google Patents

Cephalosporins

Info

Publication number
GB8419202D0
GB8419202D0 GB848419202A GB8419202A GB8419202D0 GB 8419202 D0 GB8419202 D0 GB 8419202D0 GB 848419202 A GB848419202 A GB 848419202A GB 8419202 A GB8419202 A GB 8419202A GB 8419202 D0 GB8419202 D0 GB 8419202D0
Authority
GB
United Kingdom
Prior art keywords
cephalosporins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB848419202A
Other versions
GB2145409B (en
GB2145409A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of GB8419202D0 publication Critical patent/GB8419202D0/en
Publication of GB2145409A publication Critical patent/GB2145409A/en
Application granted granted Critical
Publication of GB2145409B publication Critical patent/GB2145409B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
GB08419202A 1983-07-29 1984-07-27 Crystalline cefuroxime axetil Expired GB2145409B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838320521A GB8320521D0 (en) 1983-07-29 1983-07-29 Chemical process

Publications (3)

Publication Number Publication Date
GB8419202D0 true GB8419202D0 (en) 1984-08-30
GB2145409A GB2145409A (en) 1985-03-27
GB2145409B GB2145409B (en) 1987-02-18

Family

ID=10546505

Family Applications (2)

Application Number Title Priority Date Filing Date
GB838320521A Pending GB8320521D0 (en) 1983-07-29 1983-07-29 Chemical process
GB08419202A Expired GB2145409B (en) 1983-07-29 1984-07-27 Crystalline cefuroxime axetil

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB838320521A Pending GB8320521D0 (en) 1983-07-29 1983-07-29 Chemical process

Country Status (21)

Country Link
JP (1) JPH0613526B2 (en)
KR (1) KR910008377B1 (en)
AT (1) AT392470B (en)
AU (2) AU582121B2 (en)
BE (1) BE900241A (en)
CA (1) CA1265511A (en)
CH (1) CH662121A5 (en)
DE (1) DE3427828A1 (en)
DK (1) DK165505C (en)
ES (1) ES8601869A1 (en)
FI (1) FI76808C (en)
FR (1) FR2549837B1 (en)
GB (2) GB8320521D0 (en)
IE (1) IE57726B1 (en)
IL (1) IL72536A (en)
NL (1) NL8402372A (en)
NO (1) NO167292C (en)
NZ (1) NZ209046A (en)
PT (1) PT78985B (en)
SE (1) SE463263B (en)
ZA (1) ZA845830B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
US5063224A (en) * 1990-07-09 1991-11-05 Eli Lilly And Company R-cefuroxime axetil
IT1277426B1 (en) * 1995-08-03 1997-11-10 Acs Dobfar Spa BIOAVAILABLE CRYSTALLINE FORM OF CEFUROXIMA AXETIL
CN1111537C (en) * 1997-05-15 2003-06-18 第一制糖株式会社 The preparation method of highly pure crystalline form of cefuroxime axetil
KR100228264B1 (en) * 1997-08-02 1999-11-01 김선진 The synthetic method of crystalline cefuroxime axetil
CA2209868C (en) * 1997-08-15 2001-08-14 Bernard Charles Sherman Pharmaceutical compositions comprising cefuroxime axetil
IN186539B (en) * 1997-09-29 2001-09-29 Ranbaxy Lab Ltd
PT937727E (en) * 1998-02-20 2002-07-31 Fako Ilaclari A S PROCESS FOR PRODUCING CEFUROXIMA AZETIL CRYSTALINA SOLUVEL
IN190849B (en) 2000-07-17 2003-08-23 Ranbaxy Lab Ltd
AT411996B (en) 2000-09-11 2004-08-26 Sandoz Ag METHOD FOR PRODUCING CEFUROXIME IN THE FORM OF ITS N-BUTYL LAMONIUM SALTS
ITMI20011763A1 (en) * 2001-08-10 2003-02-10 Antibioticos Spa HIGH-PURITY CEFUROXIME AXELITE PREPARATION PROCESS
ITMI20011925A1 (en) * 2001-09-14 2003-03-14 Antibioticos Spa METHOD APPLICABLE ON INDUSTRIAL SCALE FOR THE PREPARATION OF CEFUROXIME AXETILE CRISTALLINO
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
CN100448879C (en) * 2004-07-22 2009-01-07 北京化工大学 Method for preparing unformed cefuroxime axetil
DE102005019458A1 (en) 2005-04-25 2006-10-26 Grünenthal GmbH Composition, useful in the preparation of pellets and the multi-particular-presentation form, comprises cefuroximaxetil and carrageenan of the group of lambda carrageenan, tau carrageenan and kappa carrageenan

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1571683A (en) * 1976-02-16 1980-07-16 Glaxo Operations Ltd Ester derivatives of cefuroxime
CA1094545A (en) * 1976-02-16 1981-01-27 Michael Gregson Cephalosporin antibiotics
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS577485A (en) * 1980-06-13 1982-01-14 Takeda Chem Ind Ltd Cephalosporin
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics

Also Published As

Publication number Publication date
NL8402372A (en) 1985-02-18
IE841938L (en) 1985-01-29
KR850001221A (en) 1985-03-16
NZ209046A (en) 1988-02-29
AU634965B2 (en) 1993-03-11
DK366684A (en) 1985-01-30
IE57726B1 (en) 1993-03-24
AT392470B (en) 1991-04-10
SE8403897D0 (en) 1984-07-27
PT78985A (en) 1984-08-01
CA1265511A (en) 1990-02-06
ES534695A0 (en) 1985-11-01
ZA845830B (en) 1986-03-26
NO167292C (en) 1991-10-23
GB2145409B (en) 1987-02-18
KR910008377B1 (en) 1991-10-12
JPH0613526B2 (en) 1994-02-23
NO843055L (en) 1985-01-30
DK165505B (en) 1992-12-07
FR2549837B1 (en) 1986-12-26
AU582121B2 (en) 1989-03-16
FI76808C (en) 1988-12-12
NO167292B (en) 1991-07-15
IL72536A0 (en) 1984-11-30
AU3660189A (en) 1989-10-05
GB8320521D0 (en) 1983-09-01
IL72536A (en) 1988-01-31
PT78985B (en) 1986-10-23
FR2549837A1 (en) 1985-02-01
JPS6075484A (en) 1985-04-27
SE8403897L (en) 1985-01-30
DK165505C (en) 1993-04-19
DE3427828A1 (en) 1985-02-14
DK366684D0 (en) 1984-07-27
SE463263B (en) 1990-10-29
ATA244484A (en) 1990-09-15
BE900241A (en) 1985-01-28
FI76808B (en) 1988-08-31
CH662121A5 (en) 1987-09-15
AU3125684A (en) 1985-01-31
GB2145409A (en) 1985-03-27
FI843011A (en) 1985-01-30
ES8601869A1 (en) 1985-11-01
FI843011A0 (en) 1984-07-27

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20020727