PT639563E - Utilizacao de ester de isopropilo de fluprostenol para a producao de um medicamento para o tratamento do glaucoma e hipertensao ocular - Google Patents

Utilizacao de ester de isopropilo de fluprostenol para a producao de um medicamento para o tratamento do glaucoma e hipertensao ocular

Info

Publication number
PT639563E
PT639563E PT94305752T PT94305752T PT639563E PT 639563 E PT639563 E PT 639563E PT 94305752 T PT94305752 T PT 94305752T PT 94305752 T PT94305752 T PT 94305752T PT 639563 E PT639563 E PT 639563E
Authority
PT
Portugal
Prior art keywords
glaucoma
treatment
medication
production
isopropyl ester
Prior art date
Application number
PT94305752T
Other languages
English (en)
Inventor
Louis Desantis Jr
Verney L Sallee
Paul W Zinke
Peter G Klimko
John E Bishop
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22285486&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT639563(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Publication of PT639563E publication Critical patent/PT639563E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Steroid Compounds (AREA)
PT94305752T 1993-08-03 1994-08-03 Utilizacao de ester de isopropilo de fluprostenol para a producao de um medicamento para o tratamento do glaucoma e hipertensao ocular PT639563E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/101,598 US5510383A (en) 1993-08-03 1993-08-03 Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension

Publications (1)

Publication Number Publication Date
PT639563E true PT639563E (pt) 2005-05-31

Family

ID=22285486

Family Applications (3)

Application Number Title Priority Date Filing Date
PT40778706T PT1514548E (pt) 1993-08-03 1994-08-03 Composição tópica oftálmica para o tratamento de glaucoma e hipertensão ocular
PT94305752T PT639563E (pt) 1993-08-03 1994-08-03 Utilizacao de ester de isopropilo de fluprostenol para a producao de um medicamento para o tratamento do glaucoma e hipertensao ocular
PT08100474T PT1920764E (pt) 1993-08-03 1994-08-03 Éster isopropílico de fluprostenol para utilização no tratamento de glaucoma e hipertensão ocular

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT40778706T PT1514548E (pt) 1993-08-03 1994-08-03 Composição tópica oftálmica para o tratamento de glaucoma e hipertensão ocular

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT08100474T PT1920764E (pt) 1993-08-03 1994-08-03 Éster isopropílico de fluprostenol para utilização no tratamento de glaucoma e hipertensão ocular

Country Status (13)

Country Link
US (3) US5510383A (pt)
EP (3) EP1920764B2 (pt)
JP (2) JP2791544B2 (pt)
AT (1) ATE286880T2 (pt)
AU (2) AU690120B2 (pt)
CA (1) CA2129287C (pt)
DE (1) DE69434228T2 (pt)
DK (3) DK1920764T4 (pt)
ES (3) ES2235158T5 (pt)
HK (2) HK1010717A1 (pt)
LU (2) LU92058I2 (pt)
PT (3) PT1514548E (pt)
SI (3) SI1920764T2 (pt)

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* Cited by examiner, † Cited by third party
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AU6877994A (en) 1995-02-23
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AU7748898A (en) 1998-10-01
HK1072716A1 (en) 2005-09-09
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AU704670B2 (en) 1999-04-29
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