PT3845253T - Preparação de uma injeção de libertação sustentada contedo um conjugado de um material de enchimento de ácido poli-l-láctico e um material de enchimento de ácido hialurónico e respetivo processo de fabrico - Google Patents
Preparação de uma injeção de libertação sustentada contedo um conjugado de um material de enchimento de ácido poli-l-láctico e um material de enchimento de ácido hialurónico e respetivo processo de fabricoInfo
- Publication number
- PT3845253T PT3845253T PT208069179T PT20806917T PT3845253T PT 3845253 T PT3845253 T PT 3845253T PT 208069179 T PT208069179 T PT 208069179T PT 20806917 T PT20806917 T PT 20806917T PT 3845253 T PT3845253 T PT 3845253T
- Authority
- PT
- Portugal
- Prior art keywords
- acid filler
- sustained
- poly
- manufacturing
- method therefor
- Prior art date
Links
- 239000000945 filler Substances 0.000 title 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
- 229920002674 hyaluronan Polymers 0.000 title 1
- 229960003160 hyaluronic acid Drugs 0.000 title 1
- 238000002347 injection Methods 0.000 title 1
- 239000007924 injection Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229920001432 poly(L-lactide) Polymers 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0059—Cosmetic or alloplastic implants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A61L27/58—Materials at least partially resorbable by the body
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- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020190151407A KR102183845B1 (ko) | 2019-11-22 | 2019-11-22 | 폴리-l-락틱산 필러와 히알루론산 필러 결합체를 함유하는 서방성 주사제제 및 그 제조방법 |
Publications (1)
Publication Number | Publication Date |
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PT3845253T true PT3845253T (pt) | 2023-05-12 |
Family
ID=73641918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PT208069179T PT3845253T (pt) | 2019-11-22 | 2020-11-06 | Preparação de uma injeção de libertação sustentada contedo um conjugado de um material de enchimento de ácido poli-l-láctico e um material de enchimento de ácido hialurónico e respetivo processo de fabrico |
Country Status (7)
Country | Link |
---|---|
US (1) | US11865225B2 (pt) |
EP (1) | EP3845253B1 (pt) |
KR (5) | KR102183845B1 (pt) |
BR (1) | BR112021013181A2 (pt) |
ES (1) | ES2946077T3 (pt) |
PT (1) | PT3845253T (pt) |
WO (1) | WO2021101140A1 (pt) |
Families Citing this family (1)
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CN114832156B (zh) * | 2022-05-12 | 2022-11-11 | 北美生命科学(上海)有限公司 | 一种新型医美整形填充物改性左旋聚乳酸凝胶 |
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DE60227691D1 (de) * | 2001-11-01 | 2008-08-28 | Nektar Therapeutics | Sprühtrocknungsverfahren |
KR100722607B1 (ko) * | 2006-05-11 | 2007-05-28 | 주식회사 펩트론 | 분산성 및 주사 투여능이 향상된 서방성 미립구의 제조방법 |
WO2010065784A2 (en) | 2008-12-03 | 2010-06-10 | Jakk Group, Inc. | Methods, devices, and compositions for dermal filling |
US20100189800A1 (en) | 2009-01-23 | 2010-07-29 | Peter Markland | Continous double emulsion process for making microparticles |
WO2010137888A2 (ko) * | 2009-05-27 | 2010-12-02 | 주식회사 삼양사 | 생체이용률이 향상된 난용성 약물 함유 미립구 및 그 제조 방법 |
KR101114538B1 (ko) * | 2009-07-03 | 2012-02-27 | 강원대학교산학협력단 | 온도 및 pH 민감성 고분자 코아를 함유한 마이크로 캡슐 및 그 제조방법 |
US20150366976A1 (en) | 2011-11-11 | 2015-12-24 | Miba Medical Inc. | Injectable filler |
JP2014521492A (ja) * | 2011-11-11 | 2014-08-28 | エムアイビーエイ メディカル インコーポレイテッド | 注入充填剤(フィラー){injectablefiller} |
KR101706254B1 (ko) * | 2015-11-17 | 2017-02-13 | 주식회사 동일팜텍 | 생체조직 수복 또는 재생용 고분자 미세입자의 제조방법 |
KR101852127B1 (ko) | 2016-04-11 | 2018-04-25 | 주식회사 지씨에스 | 폴리엘락틱산 필러와 히알루론산 필러 결합체의 제조방법 |
CN105879124B (zh) * | 2016-04-26 | 2019-03-19 | 华熙福瑞达生物医药有限公司 | 一种注射用左旋聚乳酸填充剂及其制备方法 |
KR20180130344A (ko) * | 2017-05-29 | 2018-12-07 | 주식회사 휴메딕스 | 미립구 제조방법 및 이에 의해 제조된 미립구 |
KR102047984B1 (ko) * | 2018-01-10 | 2019-11-22 | 주식회사 지투지바이오 | 다공성의 균일한 폴리카프로락톤 미립구 필러 및 그 제조방법 |
WO2020184744A1 (ko) * | 2019-03-08 | 2020-09-17 | 주식회사 지씨에스 | 복합체의 제조 방법 |
KR102184198B1 (ko) * | 2019-11-22 | 2020-11-30 | 주식회사 지씨에스 | 폴리-l-락틱산 필러와 히알루론산 필러 결합체 및 생체 활성물질을 함유하는 서방성 주사제제 및 그 제조방법 |
KR102183941B1 (ko) * | 2019-11-22 | 2020-11-27 | 주식회사 지씨에스 | 폴리-l-락틱산 필러와 히알루론산 필러 결합체를 함유하는 주사제제 및 그 제조방법 |
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- 2020-11-06 US US17/057,924 patent/US11865225B2/en active Active
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KR20210063262A (ko) | 2021-06-01 |
EP3845253A4 (en) | 2022-05-04 |
KR102183845B1 (ko) | 2020-11-30 |
EP3845253A1 (en) | 2021-07-07 |
BR112021013181A2 (pt) | 2021-09-28 |
WO2021101140A1 (ko) | 2021-05-27 |
EP3845253B1 (en) | 2023-03-22 |
KR102381177B1 (ko) | 2022-04-01 |
US20210369913A1 (en) | 2021-12-02 |
KR20210063260A (ko) | 2021-06-01 |
KR102381173B1 (ko) | 2022-04-01 |
US11865225B2 (en) | 2024-01-09 |
ES2946077T3 (es) | 2023-07-12 |
KR102381182B1 (ko) | 2022-04-01 |
KR20210063261A (ko) | 2021-06-01 |
KR20210063259A (ko) | 2021-06-01 |
KR102381172B1 (ko) | 2022-04-01 |
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