GB2595421B - Chenodeoxycholic acid and preparation method therefor - Google Patents

Chenodeoxycholic acid and preparation method therefor Download PDF

Info

Publication number
GB2595421B
GB2595421B GB2112484.7A GB202112484A GB2595421B GB 2595421 B GB2595421 B GB 2595421B GB 202112484 A GB202112484 A GB 202112484A GB 2595421 B GB2595421 B GB 2595421B
Authority
GB
United Kingdom
Prior art keywords
preparation
method therefor
chenodeoxycholic acid
chenodeoxycholic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB2112484.7A
Other versions
GB202112484D0 (en
GB2595421A (en
Inventor
Zhang Lei
Huang Huan
Li Shan
Zhang Heping
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhongshan Bailing Biotechnology Co Ltd
South China University of Technology SCUT
Original Assignee
Zhongshan Bailing Biotechnology Co Ltd
South China University of Technology SCUT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhongshan Bailing Biotechnology Co Ltd, South China University of Technology SCUT filed Critical Zhongshan Bailing Biotechnology Co Ltd
Publication of GB202112484D0 publication Critical patent/GB202112484D0/en
Publication of GB2595421A publication Critical patent/GB2595421A/en
Application granted granted Critical
Publication of GB2595421B publication Critical patent/GB2595421B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
GB2112484.7A 2019-03-06 2019-06-20 Chenodeoxycholic acid and preparation method therefor Active GB2595421B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201910167593.3A CN109762043B (en) 2019-03-06 2019-03-06 Chenodeoxycholic acid and preparation method thereof
PCT/CN2019/091965 WO2020177240A1 (en) 2019-03-06 2019-06-20 Chenodeoxycholic acid and preparation method therefor

Publications (3)

Publication Number Publication Date
GB202112484D0 GB202112484D0 (en) 2021-10-20
GB2595421A GB2595421A (en) 2021-11-24
GB2595421B true GB2595421B (en) 2022-09-14

Family

ID=66456617

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2112484.7A Active GB2595421B (en) 2019-03-06 2019-06-20 Chenodeoxycholic acid and preparation method therefor

Country Status (3)

Country Link
CN (1) CN109762043B (en)
GB (1) GB2595421B (en)
WO (1) WO2020177240A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109762043B (en) * 2019-03-06 2020-07-24 华南理工大学 Chenodeoxycholic acid and preparation method thereof
CN109912676B (en) * 2019-03-07 2021-08-27 上海科骊科生物技术有限公司 Preparation method of 3 beta-ursodesoxycholic acid
CN112334476B (en) * 2019-09-09 2022-03-15 邦泰生物工程(深圳)有限公司 Method for synthesizing chenodeoxycholic acid and application thereof
CN112813128A (en) * 2021-01-12 2021-05-18 中山百灵生物技术股份有限公司 Synthetic method of alloursodeoxycholic acid
CN112898370B (en) * 2021-01-25 2022-04-12 中山百灵生物技术股份有限公司 Method for extracting allochenodeoxycholic acid from duck bile
WO2023192221A1 (en) * 2022-03-29 2023-10-05 Bilayer Therapeutics, Inc. Forms and compositions of sodium chenodeoxycholate
CN115611961B (en) * 2022-10-18 2024-02-13 湖南科瑞生物制药股份有限公司 Cholic acid intermediate A2 and preparation method thereof
CN115466300B (en) * 2022-10-18 2024-10-22 湖南科瑞生物制药股份有限公司 Cholic acid intermediate A7 and synthesis method thereof
CN115637281A (en) * 2022-10-31 2023-01-24 湖南科瑞生物制药股份有限公司 Method for preparing UDCA isomer of 3 beta, 7 beta-dihydroxy-5 alpha-H
CN116355033B (en) * 2023-03-29 2024-07-26 常德云港生物科技股份有限公司 Method for removing allochenodeoxycholic acid from chenodeoxycholic acid from duck gall

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1869043A (en) * 2006-06-09 2006-11-29 沈阳化工学院 Synthesis method of chenodeoxycholic acid
CN102712672A (en) * 2009-08-25 2012-10-03 林重庆 Polyhydroxylated bile acids for treatment of biliary disorders
CN107531743A (en) * 2015-04-29 2018-01-02 正大天晴药业集团股份有限公司 Chenodeoxycholic acid derivatives
CN109762043A (en) * 2019-03-06 2019-05-17 华南理工大学 Chenodeoxycholic acid and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107383137A (en) * 2017-05-11 2017-11-24 华东师范大学 A kind of synthetic method of chenodeoxycholic acid

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1869043A (en) * 2006-06-09 2006-11-29 沈阳化工学院 Synthesis method of chenodeoxycholic acid
CN102712672A (en) * 2009-08-25 2012-10-03 林重庆 Polyhydroxylated bile acids for treatment of biliary disorders
CN107531743A (en) * 2015-04-29 2018-01-02 正大天晴药业集团股份有限公司 Chenodeoxycholic acid derivatives
CN109762043A (en) * 2019-03-06 2019-05-17 华南理工大学 Chenodeoxycholic acid and preparation method thereof

Also Published As

Publication number Publication date
GB202112484D0 (en) 2021-10-20
WO2020177240A1 (en) 2020-09-10
CN109762043B (en) 2020-07-24
CN109762043A (en) 2019-05-17
GB2595421A (en) 2021-11-24

Similar Documents

Publication Publication Date Title
GB2595421B (en) Chenodeoxycholic acid and preparation method therefor
IL304455A (en) Methods and intermediates for the preparation of bile acid derivatives
HK1254057A1 (en) Methods and intermediates for the preparation bile acid derivatives
EP3881819A4 (en) Two-dosage-form essence and preparation method therefor
AU2016417542B2 (en) Imidazopyridine thioglycolic acid derivative, preparation method therefor and application thereof
EP3629992A4 (en) Method of assisting orthodontics and orthodontics assisting system
EP3572441A4 (en) Homopolypropylene and preparation method therefor
EP3900741A4 (en) Samrna vaccine and preparation method therefor
IL279552A (en) Hemostatic complex and preparation method therefor
ZA202107279B (en) Catalytic-cracking catalyst and method for preparation thereof
EP3904555A4 (en) Ultralimit alloy and preparation method therefor
ZA202204143B (en) Film and preparation method thereof
EP3284748A4 (en) Method for preparing deoxycholic acid
EP3643311A4 (en) 4-oxo-alkylated tetramic acid compound, preparation method therefor and use thereof
EP3838890A4 (en) Method for preparing 18f-bpa and intermediate
PT3647306T (en) 4-oxo-alkylated tetramic acid compound and preparation method therefor
EP3729286A4 (en) System and method for executing instructions
IL279074A (en) Electrode assembly and method for its preparation
SG11202107530WA (en) Steroid compound, and use thereof and preparation method therefor
EP3770147A4 (en) Preparation method for azoxystrobin and intermediate thereof
GB2622972B (en) System and method for cell and tissue preparation
EP4066868A4 (en) Collagen scaffold preparation method and collagen scaffold
EP3421447A4 (en) Fatty acid compound, preparation method therefor and use thereof
EP3903730A4 (en) Covered stent and preparation method therefor
IL277066A (en) Lna-dicarboxylic acid derivatives and process for their preparation