GB2595421B - Chenodeoxycholic acid and preparation method therefor - Google Patents

Chenodeoxycholic acid and preparation method therefor Download PDF

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Publication number
GB2595421B
GB2595421B GB2112484.7A GB202112484A GB2595421B GB 2595421 B GB2595421 B GB 2595421B GB 202112484 A GB202112484 A GB 202112484A GB 2595421 B GB2595421 B GB 2595421B
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GB
United Kingdom
Prior art keywords
preparation
method therefor
chenodeoxycholic acid
chenodeoxycholic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
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GB2112484.7A
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GB202112484D0 (en
GB2595421A (en
Inventor
Zhang Lei
Huang Huan
Li Shan
Zhang Heping
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhongshan Bailing Biotechnology Co Ltd
South China University of Technology SCUT
Original Assignee
Zhongshan Bailing Biotechnology Co Ltd
South China University of Technology SCUT
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Publication of GB202112484D0 publication Critical patent/GB202112484D0/en
Publication of GB2595421A publication Critical patent/GB2595421A/en
Application granted granted Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
GB2112484.7A 2019-03-06 2019-06-20 Chenodeoxycholic acid and preparation method therefor Active GB2595421B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201910167593.3A CN109762043B (en) 2019-03-06 2019-03-06 Chenodeoxycholic acid and preparation method thereof
PCT/CN2019/091965 WO2020177240A1 (en) 2019-03-06 2019-06-20 Chenodeoxycholic acid and preparation method therefor

Publications (3)

Publication Number Publication Date
GB202112484D0 GB202112484D0 (en) 2021-10-20
GB2595421A GB2595421A (en) 2021-11-24
GB2595421B true GB2595421B (en) 2022-09-14

Family

ID=66456617

Family Applications (1)

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GB2112484.7A Active GB2595421B (en) 2019-03-06 2019-06-20 Chenodeoxycholic acid and preparation method therefor

Country Status (3)

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CN (1) CN109762043B (en)
GB (1) GB2595421B (en)
WO (1) WO2020177240A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109762043B (en) * 2019-03-06 2020-07-24 华南理工大学 Chenodeoxycholic acid and preparation method thereof
CN109912676B (en) * 2019-03-07 2021-08-27 上海科骊科生物技术有限公司 Preparation method of 3 beta-ursodesoxycholic acid
WO2021046678A1 (en) * 2019-09-09 2021-03-18 邦泰生物工程(深圳)有限公司 Method for synthesising chenodeoxycholic acid and application therefor
CN112813128A (en) * 2021-01-12 2021-05-18 中山百灵生物技术股份有限公司 Synthetic method of alloursodeoxycholic acid
CN112898370B (en) * 2021-01-25 2022-04-12 中山百灵生物技术股份有限公司 Method for extracting allochenodeoxycholic acid from duck bile
WO2023192221A1 (en) * 2022-03-29 2023-10-05 Bilayer Therapeutics, Inc. Forms and compositions of sodium chenodeoxycholate
CN115466300A (en) * 2022-10-18 2022-12-13 湖南科瑞生物制药股份有限公司 Cholic acid intermediate A7 and synthesis method thereof
CN115611961B (en) * 2022-10-18 2024-02-13 湖南科瑞生物制药股份有限公司 Cholic acid intermediate A2 and preparation method thereof
CN115637281A (en) * 2022-10-31 2023-01-24 湖南科瑞生物制药股份有限公司 Method for preparing UDCA isomer of 3 beta, 7 beta-dihydroxy-5 alpha-H

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1869043A (en) * 2006-06-09 2006-11-29 沈阳化工学院 Synthesis method of chenodeoxycholic acid
CN102712672A (en) * 2009-08-25 2012-10-03 林重庆 Polyhydroxylated bile acids for treatment of biliary disorders
CN107531743A (en) * 2015-04-29 2018-01-02 正大天晴药业集团股份有限公司 Chenodeoxycholic acid derivatives
CN109762043A (en) * 2019-03-06 2019-05-17 华南理工大学 Chenodeoxycholic acid and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107383137A (en) * 2017-05-11 2017-11-24 华东师范大学 A kind of synthetic method of chenodeoxycholic acid

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1869043A (en) * 2006-06-09 2006-11-29 沈阳化工学院 Synthesis method of chenodeoxycholic acid
CN102712672A (en) * 2009-08-25 2012-10-03 林重庆 Polyhydroxylated bile acids for treatment of biliary disorders
CN107531743A (en) * 2015-04-29 2018-01-02 正大天晴药业集团股份有限公司 Chenodeoxycholic acid derivatives
CN109762043A (en) * 2019-03-06 2019-05-17 华南理工大学 Chenodeoxycholic acid and preparation method thereof

Also Published As

Publication number Publication date
CN109762043B (en) 2020-07-24
WO2020177240A1 (en) 2020-09-10
CN109762043A (en) 2019-05-17
GB202112484D0 (en) 2021-10-20
GB2595421A (en) 2021-11-24

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