PT3558369T - Anticorpos que se ligam especificamente à il-15 humana e suas utilizações - Google Patents

Anticorpos que se ligam especificamente à il-15 humana e suas utilizações

Info

Publication number
PT3558369T
PT3558369T PT178838009T PT17883800T PT3558369T PT 3558369 T PT3558369 T PT 3558369T PT 178838009 T PT178838009 T PT 178838009T PT 17883800 T PT17883800 T PT 17883800T PT 3558369 T PT3558369 T PT 3558369T
Authority
PT
Portugal
Prior art keywords
antibodies
human
specifically bind
bind
specifically
Prior art date
Application number
PT178838009T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Cephalon Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Llc filed Critical Cephalon Llc
Publication of PT3558369T publication Critical patent/PT3558369T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/54Interleukins [IL]
    • G01N2333/5443IL-15

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
PT178838009T 2016-12-21 2017-12-21 Anticorpos que se ligam especificamente à il-15 humana e suas utilizações PT3558369T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662437143P 2016-12-21 2016-12-21

Publications (1)

Publication Number Publication Date
PT3558369T true PT3558369T (pt) 2025-05-06

Family

ID=62627610

Family Applications (1)

Application Number Title Priority Date Filing Date
PT178838009T PT3558369T (pt) 2016-12-21 2017-12-21 Anticorpos que se ligam especificamente à il-15 humana e suas utilizações

Country Status (30)

Country Link
US (2) US11267883B2 (cg-RX-API-DMAC7.html)
EP (2) EP3558369B1 (cg-RX-API-DMAC7.html)
JP (2) JP7155126B2 (cg-RX-API-DMAC7.html)
KR (2) KR20190097094A (cg-RX-API-DMAC7.html)
CN (1) CN110234349B (cg-RX-API-DMAC7.html)
AR (1) AR110414A1 (cg-RX-API-DMAC7.html)
AU (2) AU2017382850B2 (cg-RX-API-DMAC7.html)
BR (1) BR112019012570A8 (cg-RX-API-DMAC7.html)
CA (1) CA3046387A1 (cg-RX-API-DMAC7.html)
CL (1) CL2019001729A1 (cg-RX-API-DMAC7.html)
DK (1) DK3558369T3 (cg-RX-API-DMAC7.html)
EA (1) EA201991514A1 (cg-RX-API-DMAC7.html)
ES (1) ES3026508T3 (cg-RX-API-DMAC7.html)
FI (1) FI3558369T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20250482T1 (cg-RX-API-DMAC7.html)
HU (1) HUE071878T2 (cg-RX-API-DMAC7.html)
IL (1) IL267113B2 (cg-RX-API-DMAC7.html)
LT (1) LT3558369T (cg-RX-API-DMAC7.html)
MA (1) MA47130B1 (cg-RX-API-DMAC7.html)
MD (1) MD3558369T2 (cg-RX-API-DMAC7.html)
MX (2) MX2019007357A (cg-RX-API-DMAC7.html)
PE (1) PE20191497A1 (cg-RX-API-DMAC7.html)
PH (1) PH12019501453A1 (cg-RX-API-DMAC7.html)
PL (1) PL3558369T3 (cg-RX-API-DMAC7.html)
PT (1) PT3558369T (cg-RX-API-DMAC7.html)
RS (1) RS66900B1 (cg-RX-API-DMAC7.html)
SI (1) SI3558369T1 (cg-RX-API-DMAC7.html)
UA (1) UA126284C2 (cg-RX-API-DMAC7.html)
WO (1) WO2018119246A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201903848B (cg-RX-API-DMAC7.html)

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KR102794025B1 (ko) 2015-09-22 2025-04-09 트위스트 바이오사이언스 코포레이션 핵산 합성을 위한 가요성 기판
JP6871364B2 (ja) 2016-09-21 2021-05-12 ツイスト バイオサイエンス コーポレーション 核酸に基づくデータ保存
PT3558369T (pt) 2016-12-21 2025-05-06 Cephalon Llc Anticorpos que se ligam especificamente à il-15 humana e suas utilizações
CN110892485B (zh) 2017-02-22 2024-03-22 特韦斯特生物科学公司 基于核酸的数据存储
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JP2020536504A (ja) 2017-09-11 2020-12-17 ツイスト バイオサイエンス コーポレーション Gpcr結合タンパク質およびその合成
CN111565834B (zh) 2017-10-20 2022-08-26 特韦斯特生物科学公司 用于多核苷酸合成的加热的纳米孔
KR102804057B1 (ko) 2018-01-04 2025-05-07 트위스트 바이오사이언스 코포레이션 Dna 기반 디지털 정보 저장
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Also Published As

Publication number Publication date
DK3558369T3 (da) 2025-05-19
BR112019012570A2 (pt) 2019-11-26
CN110234349B (zh) 2024-03-22
US20200270339A1 (en) 2020-08-27
SI3558369T1 (sl) 2025-06-30
MA47130B1 (fr) 2025-05-30
AU2017382850A1 (en) 2019-07-04
CL2019001729A1 (es) 2019-09-13
JP2020501583A (ja) 2020-01-23
US12410247B2 (en) 2025-09-09
MX2019007357A (es) 2019-09-05
PL3558369T3 (pl) 2025-06-23
JP2022176324A (ja) 2022-11-25
KR20190097094A (ko) 2019-08-20
RS66900B1 (sr) 2025-07-31
AR110414A1 (es) 2019-03-27
LT3558369T (lt) 2025-07-25
MD3558369T2 (ro) 2025-08-31
KR20230135691A (ko) 2023-09-25
PH12019501453A1 (en) 2020-06-15
CA3046387A1 (en) 2018-06-28
JP7155126B2 (ja) 2022-10-18
UA126284C2 (uk) 2022-09-14
WO2018119246A1 (en) 2018-06-28
MX2023014081A (es) 2023-12-06
IL267113B1 (en) 2024-05-01
EP4585261A3 (en) 2025-08-13
IL267113B2 (en) 2024-09-01
KR102706743B1 (ko) 2024-09-19
IL267113A (en) 2019-08-29
EA201991514A1 (ru) 2019-12-30
AU2017382850B2 (en) 2024-11-21
FI3558369T3 (fi) 2025-05-02
ES3026508T3 (en) 2025-06-11
EP4585261A2 (en) 2025-07-16
ZA201903848B (en) 2023-02-22
PE20191497A1 (es) 2019-10-21
AU2025201185A1 (en) 2025-03-13
HUE071878T2 (hu) 2025-09-28
BR112019012570A8 (pt) 2023-01-24
EP3558369A4 (en) 2020-09-09
MA47130A (fr) 2019-10-30
US11267883B2 (en) 2022-03-08
EP3558369A1 (en) 2019-10-30
US20220127352A1 (en) 2022-04-28
HRP20250482T1 (hr) 2025-06-20
EP3558369B1 (en) 2025-03-26
CN110234349A (zh) 2019-09-13

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