PT3057993T - Métodos de tratamento das condições associadas à ativação do complemento dependente do masp-2 - Google Patents
Métodos de tratamento das condições associadas à ativação do complemento dependente do masp-2Info
- Publication number
- PT3057993T PT3057993T PT148539109T PT14853910T PT3057993T PT 3057993 T PT3057993 T PT 3057993T PT 148539109 T PT148539109 T PT 148539109T PT 14853910 T PT14853910 T PT 14853910T PT 3057993 T PT3057993 T PT 3057993T
- Authority
- PT
- Portugal
- Prior art keywords
- masp
- methods
- conditions associated
- complement activation
- treating conditions
- Prior art date
Links
- 230000024203 complement activation Effects 0.000 title 1
- 230000001419 dependent effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361892283P | 2013-10-17 | 2013-10-17 | |
| US201462020845P | 2014-07-03 | 2014-07-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3057993T true PT3057993T (pt) | 2020-11-19 |
Family
ID=52828769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT148539109T PT3057993T (pt) | 2013-10-17 | 2014-10-17 | Métodos de tratamento das condições associadas à ativação do complemento dependente do masp-2 |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US20150166675A1 (pt) |
| EP (2) | EP3057993B1 (pt) |
| JP (3) | JP2016539919A (pt) |
| KR (3) | KR20160062186A (pt) |
| CN (2) | CN105683219B (pt) |
| AU (2) | AU2014337047B2 (pt) |
| BR (1) | BR112016008409B1 (pt) |
| CA (1) | CA2926385A1 (pt) |
| CL (2) | CL2016000908A1 (pt) |
| CY (1) | CY1123776T1 (pt) |
| DK (1) | DK3057993T3 (pt) |
| ES (1) | ES2829913T3 (pt) |
| HR (1) | HRP20201733T1 (pt) |
| HU (1) | HUE051746T2 (pt) |
| IL (2) | IL283373B2 (pt) |
| LT (1) | LT3057993T (pt) |
| MX (2) | MX2016005017A (pt) |
| NZ (2) | NZ719476A (pt) |
| PL (1) | PL3057993T3 (pt) |
| PT (1) | PT3057993T (pt) |
| RS (1) | RS61351B1 (pt) |
| RU (2) | RU2718850C2 (pt) |
| SI (1) | SI3057993T1 (pt) |
| WO (1) | WO2015058143A1 (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8840893B2 (en) | 2004-06-10 | 2014-09-23 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| CN103781492A (zh) | 2011-04-08 | 2014-05-07 | 莱斯特大学 | 用于治疗与masp-2依赖性补体活化相关的状况的方法 |
| US9644035B2 (en) | 2011-04-08 | 2017-05-09 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| ES2829913T3 (es) | 2013-10-17 | 2021-06-02 | Omeros Corp | Procedimientos de tratamiento de afecciones asociadas con la activación del complemento dependiente de MASP-2 |
| UA124094C2 (uk) * | 2015-11-09 | 2021-07-21 | Омерос Корпорейшн | Спосіб лікування стану, пов'язаного з masp-2-залежною активацією комплементу |
| EP3400012A4 (en) * | 2016-01-05 | 2019-12-11 | University Of Leicester | PROCESS FOR INHIBITING FIBROSIS IN A NEEDED SUBJECT |
| CN115137816A (zh) | 2016-03-31 | 2022-10-04 | 奥默罗斯公司 | 抑制有需要的受试者的血管发生的方法 |
| JOP20170170B1 (ar) * | 2016-08-31 | 2022-09-15 | Omeros Corp | صيغ لجسم مضاد تثبيطية لـ masp-2 بتركيز عالي ولزوجة منخفضة وأطقم، وطرق |
| JOP20190068A1 (ar) * | 2016-10-13 | 2019-04-01 | Omeros Corp | طرق لتقليل البول البروتيني في خاضع بشري يعاني من الاعتلال الكلوي a الناتج عن الجلوبيولين المناعي |
| TWI818919B (zh) * | 2017-08-15 | 2023-10-21 | 美商歐米諾斯公司 | 用於治療和／ 或預防與造血幹細胞移植有關的移植物抗宿主病和／ 或瀰漫性肺泡出血和／ 或靜脈閉塞性病的方法 |
| MX2020002077A (es) * | 2017-08-25 | 2020-03-24 | Omeros Corp | Formulaciones de anticuerpos inhibidores de masp-2 de baja viscosidad altamente concentradas, kits y metodos para el tratamiento de sujetos que padecen sindrome hemolitico atipico. |
| CN108171772B (zh) * | 2017-12-28 | 2021-11-19 | 中国地质调查局西安地质调查中心 | 利用mapGIS、CJKCOOR_Ver和DELF3D提取河流边界的方法 |
| US20200140570A1 (en) * | 2018-06-22 | 2020-05-07 | Omeros Corporation | Compositions and Methods of Inhibiting MASP-2 for the Treatment of Various Thrombotic Diseases and Disorders |
| US11161900B2 (en) * | 2018-12-13 | 2021-11-02 | Argenx Bvba | Antibodies that specifically bind to human complement factor C2b |
| CN111134250A (zh) * | 2019-12-03 | 2020-05-12 | 海南大学 | 一种草地贪夜蛾幼虫食用人工饲料的配方和制作方法 |
| US12030853B2 (en) | 2019-12-04 | 2024-07-09 | Omeros Corporation | MASP-2 inhibitors and methods of use |
| WO2021113686A1 (en) | 2019-12-04 | 2021-06-10 | Omeros Corporation | Masp-2 inhibitors and methods of use |
| JP2023504543A (ja) | 2019-12-04 | 2023-02-03 | オメロス コーポレーション | Ｍａｓｐ－２阻害剤および使用方法 |
| CA3159167A1 (en) | 2019-12-04 | 2021-06-10 | Neil S. Cutshall | Masp-2 inhibitors and methods of use |
| CN115215937B (zh) * | 2021-04-15 | 2023-05-26 | 上海麦济生物技术有限公司 | 抗人masp-2抗体及其制备方法和应用 |
| CN115300608B (zh) * | 2021-05-06 | 2023-06-02 | 四川大学 | 一种利用甘露糖结合凝集素阻断新冠病毒感染的方法 |
| IL313331A (en) | 2021-12-10 | 2024-08-01 | Omeros Corp | Therapeutic antibodies that bind to the SERINE PROTEASE domain of MASP-2 and uses thereof |
| US20240228499A1 (en) | 2022-11-30 | 2024-07-11 | Omeros Corporation | Masp-2 inhibitors and methods of use |
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| CA3102252A1 (en) * | 2004-06-10 | 2005-12-29 | Omeros Corporation | Methods for treating conditions associated with masp-2 dependent complement activation |
| US8840893B2 (en) | 2004-06-10 | 2014-09-23 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
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| US9644035B2 (en) * | 2011-04-08 | 2017-05-09 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| CN103781492A (zh) * | 2011-04-08 | 2014-05-07 | 莱斯特大学 | 用于治疗与masp-2依赖性补体活化相关的状况的方法 |
| CN107011443B (zh) * | 2011-05-04 | 2021-04-30 | 奥默罗斯公司 | 用于抑制masp-2依赖的补体活化的组合物 |
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| ES2829913T3 (es) | 2013-10-17 | 2021-06-02 | Omeros Corp | Procedimientos de tratamiento de afecciones asociadas con la activación del complemento dependiente de MASP-2 |
| UA124094C2 (uk) | 2015-11-09 | 2021-07-21 | Омерос Корпорейшн | Спосіб лікування стану, пов'язаного з masp-2-залежною активацією комплементу |
-
2014
- 2014-10-17 ES ES14853910T patent/ES2829913T3/es active Active
- 2014-10-17 JP JP2016523966A patent/JP2016539919A/ja active Pending
- 2014-10-17 RU RU2016118769A patent/RU2718850C2/ru active
- 2014-10-17 SI SI201431703T patent/SI3057993T1/sl unknown
- 2014-10-17 KR KR1020167012842A patent/KR20160062186A/ko not_active IP Right Cessation
- 2014-10-17 US US14/517,750 patent/US20150166675A1/en not_active Abandoned
- 2014-10-17 IL IL283373A patent/IL283373B2/en unknown
- 2014-10-17 RU RU2020111211A patent/RU2020111211A/ru unknown
- 2014-10-17 NZ NZ719476A patent/NZ719476A/en unknown
- 2014-10-17 PT PT148539109T patent/PT3057993T/pt unknown
- 2014-10-17 DK DK14853910.9T patent/DK3057993T3/da active
- 2014-10-17 HU HUE14853910A patent/HUE051746T2/hu unknown
- 2014-10-17 WO PCT/US2014/061236 patent/WO2015058143A1/en active Application Filing
- 2014-10-17 CA CA2926385A patent/CA2926385A1/en active Pending
- 2014-10-17 RS RS20201362A patent/RS61351B1/sr unknown
- 2014-10-17 AU AU2014337047A patent/AU2014337047B2/en active Active
- 2014-10-17 PL PL14853910T patent/PL3057993T3/pl unknown
- 2014-10-17 NZ NZ757986A patent/NZ757986A/en unknown
- 2014-10-17 MX MX2016005017A patent/MX2016005017A/es unknown
- 2014-10-17 KR KR1020247020232A patent/KR20240101700A/ko unknown
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